Check out our most popular compounded medications! Get Started
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Prepared to a prescriber's order for one patient. Not FDA-approved.
Vitamin E is a fat-soluble antioxidant vitamin that compounding pharmacies include in oral capsules and liquids and in topical preparations.
Vitamin E is the name for a group of fat-soluble compounds with antioxidant activity that help protect cell membranes. Of its eight natural forms, alpha-tocopherol is the only one recognized to meet human needs. The natural form (RRR or d-alpha-tocopherol) is about twice as active as the synthetic form (all-rac or dl-alpha-tocopherol). In the United States, vitamin E is sold mainly as a dietary supplement; FDA does not approve dietary supplements before they are marketed, and no prescription vitamin E drug product is listed on DailyMed. Deficiency is uncommon and is usually linked to fat malabsorption, cholestatic liver disease or rare inherited disorders. A prescriber may order vitamin E compounded in a specific form, as a liquid, or free of certain allergens or additives. Compounded preparations are not FDA-approved and require a prescription.
Vitamin E from food is not considered harmful. High-dose supplements may raise the risk of bleeding, including bleeding in the brain (hemorrhagic stroke), because vitamin E can reduce platelet clumping. Large doses taken with blood thinners or antiplatelet medicines such as warfarin can increase bleeding risk, so tell your prescriber if you take these or have surgery planned. Oncologists generally advise against antioxidant supplements during chemotherapy or radiation, and antioxidant combinations blunted the HDL rise from simvastatin with niacin. Do not use vitamin E if you are allergic to it or to anything in the preparation. High-dose supplements have been linked in some studies to bleeding problems and, in a few analyses, to small increases in overall mortality. Vitamin E is a normal part of breast milk, and LactMed notes supplementation from prenatal vitamins can safely increase milk levels modestly; higher amounts have not been studied. Talk to your prescriber or pharmacist about unusual bruising or bleeding.
Alpha-tocopherol functions as an antioxidant that protects cell membranes. Absorption depends on bile and pancreatic function: pancreatic enzymes cleave tocopheryl esters, and chylomicrons carry alpha-tocopherol through the lymphatics to the liver. StatPearls notes that long-standing cholestasis (primary biliary cholangitis, primary sclerosing cholangitis, decompensated cirrhosis), bowel resection and small-intestinal disease can cause deficiency, which presents with neuropathy affecting gait and proprioception and with hemolysis. ODS describes deficiency in abetalipoproteinemia and ataxia with vitamin E deficiency (AVED). Alpha-tocopherol is metabolized by hepatic CYP450 enzymes, so watch for interactions with inducers and inhibitors. There is no FDA-labeled indication because no prescription product exists. Dosing and choice of natural or synthetic form are per prescriber. Levels are not routinely monitored because deficiency is uncommon, but StatPearls notes serum alpha-tocopherol measurement is warranted in fat-malabsorption disorders such as cystic fibrosis, chronic pancreatitis and cholestatic disease. Monitor for bleeding in patients on anticoagulant or antiplatelet therapy and around surgery. Vitamin E is not a controlled substance.
Wash your hands. If the suppository is soft, chill it in its wrapper in the refrigerator or under cool water for a few minutes, then unwrap it. For rectal use, coat the tip with a water-soluble lubricant (not petroleum jelly), lie on your side with your upper knee bent, and insert it pointed end first past the muscle at the opening. For vaginal use, lie on your back with knees bent and insert it as far as it comfortably goes, by finger or applicator; bedtime use limits leakage, and a panty liner protects clothing. Stay lying down about 15 minutes. Wash your hands.
Suppositories are nonaqueous, so under USP <795> they can carry a beyond-use date of up to 180 days at controlled room temperature or in the refrigerator when no other stability data apply. Storage depends on the base: fatty bases can soften at room temperature and may be labeled for the refrigerator, while polyethylene glycol bases usually do not need refrigeration. Keep them cool so they do not melt, and refrigerate them if your label says to.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Insert 1 unwrapped suppository
