How to Prescribe Ketamine Nasal Spray

Learn how to prescribe Ketamine Nasal Spray as a controlled compound.

Effective January 2, 2020, Rhode Island prescribers must sign and transmit electronic prescriptions in schedules II, III, IV, and V to comply with RI Law §21-28-3.18 section 3.

How to Electronically Prescribe Ketamine Nasal Spray

  1. Select Ketamine (bulk) powder as the drug.  The drug selected needs to be a controlled substance
  2. In the instructions, directions, or notes field, please indicate:
    a. The concentration of the preparation (Ketamine 10mg/ml Nasal Spray)
    b. The directions (ex. Inhale 1 spray in each nostril every 4) 6 hours as needed)
    c. An ICD-10 diagnosis code
    d. A quantity of dose units dispensed. Federal law prohibits more than 100 dosage units
    e. Refills (maximum of 5)
  3. Do not use the name brand (Ketalar®) when prescribing Ketamine containing compounds

The prescription needs to be sent by the prescriber with the controlled substance selected as the active drug for the Electronic Prescriptions for Controlled Substances (EPCS) signature to be validated.

Most Common Formulations

Here are the most requested formulations of this controlled compound:

  • Ketamine 10mg/ml Nasal Spray
  • Ketamine 50mg/ml Nasal Spray
  • Ketamine 100mg/ml Nasal Spray
  • Ketamine 25mg/ml / Lidocaine HCl 4% Nasal Spray

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