How to Prescribe Ketamine Oral Suspension

Effective January 2, 2020, Rhode Island prescribers must sign and transmit electronic prescriptions in schedules II, III, IV, and V to comply with RI Law §21-28-3.18 section 3.

How to Electronically Prescribe Ketamine Oral Suspension

1. Select Ketamine (bulk) powder as the drug.  The drug selected needs to be a controlled substance
2. In the instructions, directions, or notes field, please indicate:
   a. The concentration of the preparation (Ketamine 50mg/ml Oral Suspension)
   b. The directions (ex. Take 0.25ml by mouth 3 times daily)
   c. An ICD-10 diagnosis code
   d. A quantity of dose units dispensed. Federal law prohibits more than 100 dosage units
   e. Refills (maximum of 5)
3. Do not use the name brand (Ketalar®) when prescribing Ketamine containing compounds

The prescription needs to be sent by the prescriber with the controlled substance selected as the active drug for the Electronic Prescriptions for Controlled Substances (EPCS) signature to be validated.

Most Common Formulations

Here are the most requested formulations of this controlled compound:

• Gabapentin 6%/Ketamine 3%/Amitriptyline HCl 2%/Lidocaine HCl 0.5% Oral Rinse
• Ketamine 0.4% Oral Rinse
• Ketamine 100mg/ml Oral Suspension
• Ketamine 50mg/ml Oral Suspension