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Alprostadil 10mcg/ml/Papaverine HCl 30 mg/ml/Phentolamine Mesylate 1mg/ml Injection Solution

Bayview Pharmacy's compounded Alprostadil 5 Mcg/ml To 45 Mcg/ml/Papaverine HCl 15 mg/ml To 30 mg/ml/Phentolamine Mesylate 0.4 mg/ml To 5 mg/ml Injection Solution is a specialized medication designed to treat conditions such as erectile dysfunction, Peyronie's disease, priapism, Raynaud's syndrome, and vasospasm. The medication is contained in a small glass container and is administered via injection using a syringe, allowing for precise dosing.

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Dosing Calculator

Get general dosing information for a patient by using this calculator.
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Formula Information

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Bayview Pharmacy is pleased to provide a specially compounded injection solution containing Alprostadil ranging from 5 mcg/ml to 45 mcg/ml, Papaverine HCl from 15 mg/ml to 30 mg/ml, and Phentolamine Mesylate from 0.4 mg/ml to 5 mg/ml. This unique formulation is designed to address a variety of health conditions, including erectile dysfunction, Raynaud's phenomenon, and hypertensive crises.

Alprostadil is a potent vasodilator that works by relaxing the smooth muscle in the penis, thereby enhancing blood flow and improving erectile function. Papaverine HCl, a smooth muscle relaxant, operates in a similar manner, promoting increased blood flow and improved erectile function. Phentolamine Mesylate, an alpha-adrenergic blocker, mitigates the effects of vasoconstriction, further facilitating improved blood flow and erectile function.

This compounded injection solution is a highly effective treatment option for erectile dysfunction, Raynaud's phenomenon, and hypertensive crises. It is crucial to understand that this formulation should only be administered under the guidance of a healthcare provider. If you have any queries or require further information about this formulation, please do not hesitate to contact us at Bayview Pharmacy.

The medication is contained in a small glass container designed to hold sterile liquid medication, typically administered through injection using a syringe. A syringe is inserted into the container and filled to the desired amount for accurate dosing. This method ensures the precise delivery of the medication, contributing to its efficacy and safety.

Drug Interactions

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Alprostadil, Papaverine HCl, and Phentolamine Mesylate injection solution is a compounded formulation designed for the treatment of erectile dysfunction and Peyronie's disease. This potent combination of medications works synergistically to increase blood flow to the penis, facilitating an erection. Alprostadil, a prostaglandin, Papaverine HCl, an antispasmodic, and Phentolamine Mesylate, an alpha-adrenergic blocker, all contribute to the relaxation of smooth muscle cells.

Peyronie's disease, a condition characterized by the curvature of the penis due to scar tissue, can also be treated with this medication. The combined effect of these medications can help alleviate the symptoms of this condition.

Patients should be informed that this medication may cause side effects such as dizziness, flushing, headache, and nausea. A prolonged erection, which can be painful and necessitate medical attention, may also occur. It is crucial that patients do not take this medication if they are currently on nitrates or alpha-blockers, as these can cause a dangerous drop in blood pressure when combined with this medication.

Prescribers should exercise caution when prescribing this medication. It should not be used in patients with a history of heart disease, stroke, or blood clots. Additionally, patients with a history of priapism, a condition characterized by a prolonged and painful erection, should avoid this medication. Patients with a history of liver or kidney disease should also avoid this medication, as it can lead to an increase in side effects.

If you have any questions about this formulation or its application in treating these disease states, please do not hesitate to reach out for further information.

How Does it Work

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Alprostadil 5 Mcg/ml To 45 Mcg/ml/Papaverine HCl 15 mg/ml To 30 mg/ml/Phentolamine Mesylate 0.4 mg/ml To 5 mg/ml Injection Solution is a compounded formulation designed to treat erectile dysfunction. This solution combines three active ingredients: Alprostadil, Papaverine HCl, and Phentolamine Mesylate.

Alprostadil is a potent vasodilator that works by relaxing the muscles in the penis, thereby facilitating increased blood flow and enabling an erection. The dose range for Alprostadil in this formulation is 5 to 45 mcg/ml.

Papaverine HCl, like Alprostadil, is a vasodilator that aids in relaxing the penile muscles, promoting increased blood flow and contributing to the achievement of an erection. The dose range for Papaverine HCl in this formulation is 15 to 30 mg/ml.

Phentolamine Mesylate is an alpha-adrenergic blocker. Its role in this formulation is to prevent the body from reabsorbing the blood that has been released into the penis, thereby allowing for a longer-lasting erection. The dose range for Phentolamine Mesylate in this formulation is 0.4 to 5 mg/ml.

This combination of medications is administered via direct injection into the penis. The dosage is adjusted based on the patient's response to the treatment. It is important to note that the use of this formulation should be under the guidance of a healthcare professional. If you have any questions about this formulation or its mechanism of action, please consult your healthcare provider.

Other Uses

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This compounded formulation of Alprostadil 5 Mcg/ml To 45 Mcg/ml/Papaverine HCl 15 mg/ml To 30 mg/ml/Phentolamine Mesylate 0.4 mg/ml To 5 mg/ml Injection Solution is a versatile medication used in the treatment of a variety of conditions. Primarily, it is used to address erectile dysfunction, Peyronie's disease, priapism, Raynaud's syndrome, and vasospasm. It also has applications in the treatment of ischemic ulcers, chronic venous insufficiency, and thrombophlebitis. Beyond these, it has been found effective in managing post-surgical pain, post-traumatic pain, and post-radiation pain. This formulation has also been used to alleviate chronic pain associated with cancer, peripheral neuropathy, fibromyalgia, and rheumatoid arthritis. If you have any questions about the use of this formulation, please reach out for further information.

Frequently Asked Questions

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What is Alprostadil 10mcg/ml/Papaverine HCl 30 mg/ml/Phentolamine Mesylate 1mg/ml Injection Solution?

This is a compounded medication that contains three active ingredients: Alprostadil, Papaverine HCl, and Phentolamine Mesylate. It is typically used for the treatment of erectile dysfunction.

How is this medication administered?

This medication is typically administered through injection using a syringe. The syringe is inserted into the small glass container and filled to the desired amount for proper dosing.

What is the purpose of the small glass container?

The small glass container is designed to hold the sterile liquid medication. It ensures that the medication remains uncontaminated until it is ready to be administered.

How do I determine the correct dose?

The correct dose will be determined by your healthcare provider, based on your specific condition and response to therapy. Always follow your healthcare provider's instructions.

What should I do if I miss a dose?

If you miss a dose, contact your healthcare provider for instructions. Do not double the dose to catch up.

What are the potential side effects of this medication?

Side effects can include pain at the injection site, priapism (prolonged or painful erection), and potential changes in blood pressure. If you experience any of these side effects, contact your healthcare provider immediately.

Can I use this medication if I am pregnant or breastfeeding?

This medication is typically used in men for erectile dysfunction. However, if a woman comes into contact with this medication, she should consult her healthcare provider, especially if she is pregnant or breastfeeding.

Can I drink alcohol while using this medication?

Alcohol may interact with this medication and increase the risk of certain side effects. It is best to consult your healthcare provider before consuming alcohol while using this medication.

What should I do in case of an overdose?

If you suspect an overdose, seek immediate medical attention or call a poison control center right away.

How should I store this medication?

This medication should be stored in a cool, dry place, away from light and heat. Always keep it out of reach of children and pets.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
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