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Apomorphine HCl 1 mg/Phentolamine Mesylate 2 mg/Tadalafil 10 mg Oral Capsules

FDA-approved generic
Dose form
Capsules
Active ingredients
Apomorphine Hydrochloride
Tadalafil
Phentolamine Mesylate

Apomorphine HCl 1 mg/Phentolamine Mesylate 2 mg/Tadalafil 10 mg Oral Capsules are a specialized formulation designed by our expert compounding pharmacists at Bayview Pharmacy. This formulation is a solid dosage form composed of two gelatin or vegetarian shells that enclose the active ingredients - Apomorphine HCl, Phentolamine Mesylate, and Tadalafil. These capsules are designed for easy swallowing and provide a precise dosage of the active ingredients.

This formulation is specifically designed to treat certain disease states. Apomorphine HCl is used to treat Parkinson's disease symptoms such as stiffness, tremors, muscle spasms, and poor muscle control. Phentolamine Mesylate is used to prevent and control high blood pressure during surgery and certain medical procedures. Tadalafil is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate).

By combining these three active ingredients into one convenient capsule, we aim to provide a comprehensive treatment option for patients suffering from these disease states. As compounding pharmacists, we are committed to providing personalized medication solutions to meet the unique needs of each patient.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Apomorphine Hydrochloride
Tadalafil
Phentolamine Mesylate
Capsules
65305ef7d053cb7b8c1b4590
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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This formulation combines Apomorphine HCl, Phentolamine Mesylate, and Tadalafil in a solid dosage form, specifically an oral capsule. The capsule is composed of two gelatin or vegetarian shells that enclose the medication. This design allows for convenient and easy swallowing, and provides a precise dosage of the active ingredients.

Apomorphine HCl is a non-selective dopamine agonist that is used for the treatment of Parkinson's disease. It works by stimulating dopamine receptors in the brain, which helps to improve motor function. However, in this formulation, it is used for its pro-erectile properties. It stimulates the hypothalamic pathways, which leads to an erection.

Phentolamine Mesylate is an alpha-adrenergic blocker. It is typically used to manage hypertension, but in this formulation, it is used for its ability to promote blood flow to the penis, thereby aiding in the achievement and maintenance of an erection.

Tadalafil is a phosphodiesterase-5 (PDE5) inhibitor. It is commonly used to treat erectile dysfunction and benign prostatic hyperplasia. It works by relaxing the muscles in the blood vessels, increasing blood flow to certain areas of the body. In this formulation, it aids in the treatment of erectile dysfunction.

This combination of Apomorphine HCl, Phentolamine Mesylate, and Tadalafil in an oral capsule form provides a comprehensive approach to the treatment of erectile dysfunction. It targets different pathways to promote and maintain an erection.

As with any medication, it is important to use this formulation under the guidance of a healthcare provider. Side effects may include dizziness, flushing, headache, and indigestion. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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This formulation combines Apomorphine HCl, Phentolamine Mesylate, and Tadalafil in a solid dosage form. These active ingredients work together to treat conditions such as erectile dysfunction and Parkinson's disease. Apomorphine HCl is a dopamine agonist that helps to improve motor function in patients with Parkinson's disease. Phentolamine Mesylate is an alpha-adrenergic blocker that helps to relax and widen blood vessels, improving blood flow. Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor that also helps to increase blood flow, particularly to the penis, aiding in the treatment of erectile dysfunction.

Apomorphine HCl can interact with certain antiemetics, such as ondansetron, increasing the risk of severe hypotension and loss of consciousness. It can also interact with antihypertensive drugs, leading to an increased risk of hypotension. Alcohol and other CNS depressants can enhance the sedative effects of Apomorphine HCl.

Phentolamine Mesylate can interact with beta-blockers, leading to an increased risk of hypotension and tachycardia. It can also interact with erectile dysfunction drugs, such as sildenafil, vardenafil, and avanafil, leading to an increased risk of priapism (prolonged and painful erection).

Tadalafil can interact with nitrates, leading to a significant drop in blood pressure. It can also interact with alpha-blockers, increasing the risk of hypotension. Other PDE5 inhibitors and protease inhibitors can increase the plasma concentration of Tadalafil, leading to an increased risk of side effects.

It's crucial for patients to inform their healthcare provider of all medications they are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. This will help to minimize the risk of drug interactions. Patients should also avoid consuming alcohol while taking this medication, as it can enhance certain side effects.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us.

How Does it Work

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The Apomorphine HCl 1 mg/Phentolamine Mesylate 2 mg/Tadalafil 10 mg Oral Capsules are a combination medication designed to treat erectile dysfunction. Each of the three active ingredients plays a unique role in addressing this condition.

Apomorphine HCl is a dopamine agonist that works by activating dopamine receptors in the brain. Dopamine is a neurotransmitter that plays a crucial role in the regulation of sexual behavior. By stimulating these receptors, Apomorphine HCl helps to enhance the signals that trigger an erection.

Phentolamine Mesylate is an alpha-adrenergic blocker. It works by relaxing the smooth muscles in the blood vessels of the penis, which allows for increased blood flow. This increased blood flow is essential for achieving and maintaining an erection.

Tadalafil is a type of medication known as a phosphodiesterase-5 (PDE5) inhibitor. It works by blocking the enzyme PDE5, which is responsible for the breakdown of a substance called cyclic guanosine monophosphate (cGMP) in the smooth muscle cells lining the blood vessels supplying the penis. By inhibiting PDE5, Tadalafil allows cGMP to accumulate. The increased cGMP relaxes the smooth muscles, which results in an expanded blood flow to the penis and an erection upon sexual stimulation.

The combination of these three active ingredients in one capsule allows for a multi-faceted approach to treating erectile dysfunction. The capsule form ensures a precise dosage of each ingredient and provides a convenient method of administration. The solid dosage form, composed of two gelatin or vegetarian shells, encloses the medication, allowing for easy swallowing.

It's important to note that this medication does not provide an instant erection. Sexual stimulation is still necessary to achieve an erection after taking the capsule. The medication is designed to improve the body's natural response to sexual stimulation.

If you have any questions about this formulation, how it works, or how it may benefit you, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Frequently Asked Questions

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What are the active ingredients in these oral capsules?

The active ingredients in these capsules are Apomorphine HCl 1 mg, Phentolamine Mesylate 2 mg, and Tadalafil 10 mg.

What are the capsules made of?

The capsules are made of two shells, either gelatin or vegetarian, that enclose the medication.

Why are these oral capsules a solid dosage form?

These capsules are considered a solid dosage form as they are composed of two shells that enclose precisely measured active ingredients.

What is the advantage of using these solid dosage form capsules?

These capsules offer a convenient and easy method of consuming medication, ensuring accurate dosage.

Are these capsules easy to swallow?

Yes, the purpose of their design is to enable convenient and easy swallowing.

Are these capsules suitable for vegetarians?

Yes, they can be. The capsules can be made of either gelatin or vegetarian shells.

How is the dosage of each ingredient in these capsules determined?

The capsules are carefully measured and manufactured to contain a precise dose of each active ingredient: Apomorphine HCl 1mg, Phentolamine Mesylate 2mg, and Tadalafil 10mg.

Can I open these capsules and take the medication directly?

No, the shells of the capsules are meant to be swallowed whole as they ensure the correct dosages of each active ingredient are consumed.

Can I adjust the doses of the individual components in the capsules?

No. The dosage of each component is measured and manufactured precisely. Modifying the capsules can lead to unintentional overdosing or under-dosing.

What happens if I miss one dose of the Apomorphine HCl, Phentolamine Mesylate, Tadalafil capsules?

It is always recommended to maintain a consistent medication schedule. However, if you miss a dose, you should take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule. Do not double up on a dose to make up for the missed one. Always consult with your healthcare professional for specific instructions.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Apomorphine HCl 1 mg/Phentolamine Mesylate 2 mg/Tadalafil 10 mg Oral Capsules
Capsules
90 capsules
controlled

Take 1 capsule by mouth

Once daily as needed