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Vancomycin 500 mg/60 ml/Metronidazole 250 mg/60 ml Rectal Suspension Enema

Bayview Pharmacy offers a compounded formulation of Vancomycin 500 mg/60 ml/Metronidazole 250 mg/60 ml Rectal Suspension Enema. This ready-to-use liquid formulation is contained in pre-filled enema bottles for rectal administration. It provides a convenient and hygienic method for targeted treatment of conditions such as Clostridioides Difficile Infection, Ulcerative Colitis, Crohn's Disease, Proctitis, and Anal Fissures. The measured dose of the solution allows for easy and controlled application without the need for additional preparation.

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Enema
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Formula Information

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Bayview Pharmacy is pleased to present our specially compounded formulation of Vancomycin 500 mg/60 ml/Metronidazole 250 mg/60 ml Rectal Suspension Enema. This unique formulation is specifically designed to address a range of disease states, including bacterial infections, inflammatory bowel disease, and Clostridium difficile infections.

Vancomycin, a potent antibiotic, is effective against a wide array of bacterial infections, including those caused by Staphylococcus aureus, Streptococcus pneumoniae, and Enterococcus faecalis. Metronidazole, another antibiotic, is primarily used to treat inflammatory bowel disease and Clostridium difficile infections. The combination of these two antibiotics in our formulation enhances the treatment's effectiveness against these conditions.

This formulation is a ready-to-use liquid contained in pre-filled enema bottles, designed for rectal administration. This method of delivery provides a convenient, hygienic, and targeted treatment for the aforementioned conditions. It offers a measured dose of the solution for easy and controlled application, eliminating the need for additional preparation.

Administered as a rectal enema, this formulation ensures safe and effective delivery of medication directly to the affected area. This method of administration is particularly beneficial in treating conditions that affect the lower gastrointestinal tract, as it allows for direct contact with the site of infection or inflammation.

If you have any queries about this formulation or its application in treating your patient's condition, please do not hesitate to contact us at Bayview Pharmacy. Our team is committed to assisting you in finding the most suitable treatment option for your patient.

Drug Interactions

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Vancomycin 500 mg/60 ml/Metronidazole 250 mg/60 ml Rectal Suspension Enema is a ready-to-use liquid formulation that is contained in pre-filled enema bottles. This formulation is designed for rectal administration, providing a convenient and hygienic method for targeted treatment of bacterial infections of the lower gastrointestinal tract. These infections include Clostridium difficile-associated diarrhea and colitis. The formulation offers a measured dose of the solution for easy and controlled application without the need for additional preparation.

It is important to note that this formulation should be used with caution in patients with renal impairment, as vancomycin is known to accumulate in the renal system. Patients should be monitored for signs of toxicity, including nephrotoxicity, ototoxicity, and neurotoxicity. Metronidazole, another active ingredient in this formulation, may interact with alcohol, resulting in a disulfiram-like reaction. Patients should be advised to avoid alcohol while taking this medication.

Furthermore, metronidazole may interact with other medications, including warfarin, phenytoin, and lithium. Patients should be monitored for signs of bleeding or changes in lithium levels. It is crucial to consult with a healthcare provider before starting this medication to ensure it is safe and appropriate for the patient's condition. If you have any questions or concerns, please do not hesitate to reach out for further information.

How Does it Work

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Vancomycin 500 mg/60 ml/Metronidazole 250 mg/60 ml Rectal Suspension Enema is a compounded medication specifically designed to treat a range of conditions such as bacterial infections, inflammatory bowel disease, and ulcerative colitis. This medication is administered rectally in the form of an enema, a liquid solution that is inserted into the rectum. The combination of vancomycin and metronidazole in the formulation works synergistically to combat the infection and alleviate inflammation. Vancomycin functions by inhibiting bacterial growth, while metronidazole eliminates the bacteria, thereby reducing the symptoms associated with the infection and inflammation.

The Vancomycin 500 mg/60 ml/Metronidazole 250 mg/60 ml Rectal Suspension Enema is a ready-to-use liquid formulation contained in pre-filled enema bottles. This design provides a convenient and hygienic method for targeted treatment, offering a measured dose of the solution for easy and controlled application without the need for additional preparation. To administer, the patient should lie on their left side with their knees bent and their feet flat on the floor. The enema should be inserted into the rectum and held in place for 10-15 minutes. After the enema has been inserted, the patient should remain in the same position for an additional 10-15 minutes. The enema should then be removed and the patient should remain in the same position for an additional 10-15 minutes.

It is crucial to use the Vancomycin 500 mg/60 ml/Metronidazole 250 mg/60 ml Rectal Suspension Enema as directed by the prescriber. Following the instructions carefully and not exceeding the recommended dosage is of utmost importance. If you have any questions about how to use this medication, it is recommended to consult with your healthcare provider.

Other Uses

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This compounded formulation of Vancomycin 500 mg/60 ml/Metronidazole 250 mg/60 ml Rectal Suspension Enema is a ready-to-use liquid solution, conveniently contained in pre-filled enema bottles for rectal administration. It is designed to provide a hygienic and targeted treatment for a variety of conditions, including constipation and bowel cleansing, as well as a method for medication delivery. The measured dose of the solution allows for easy and controlled application, eliminating the need for additional preparation.

Aside from its primary uses, this formulation can also be employed in the treatment of other conditions such as perianal abscesses, proctitis, and anal fistulas. It has been found effective in reducing inflammation and pain associated with these conditions. Furthermore, it can be used to minimize the risk of infection in patients who have undergone rectal surgery or radiation therapy to the rectal area.

Patients should be informed that this formulation may cause side effects such as nausea, vomiting, and diarrhea. It is also important to note that this formulation may interact with other medications they are currently taking. Therefore, it is crucial to consult with a healthcare provider before starting this treatment. If you have any questions or concerns about the use of this formulation, please do not hesitate to reach out for further information.

Frequently Asked Questions

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What is the Vancomycin 500 mg/60 ml/Metronidazole 250 mg/60 ml Rectal Suspension Enema?

This is a ready-to-use liquid formulation contained in pre-filled enema bottles. It is designed for rectal administration and is used for the targeted treatment of constipation, bowel cleansing, or medication delivery.

How is this formulation administered?

This formulation is administered rectally. It provides a convenient and hygienic method for treatment, offering a measured dose of the solution for easy and controlled application without the need for additional preparation.

What is the purpose of this formulation?

This formulation is used for the targeted treatment of constipation, bowel cleansing, or medication delivery. It provides a measured dose of the solution for easy and controlled application.

What are the active ingredients in this formulation?

The active ingredients in this formulation are Vancomycin 500 mg and Metronidazole 250 mg per 60 ml of the solution.

Do I need to prepare the solution before use?

No, the solution comes in a pre-filled enema bottle and is ready to use. There is no need for additional preparation.

How do I store this formulation?

Store this formulation as directed by your healthcare provider. Typically, it should be stored in a cool, dry place away from direct sunlight.

What should I do if I miss a dose?

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

What should I do in case of an overdose?

In case of an overdose, seek immediate medical attention or call your healthcare provider right away.

Can I use this formulation if I am pregnant or breastfeeding?

Consult your healthcare provider before using this formulation if you are pregnant or breastfeeding. They will be able to advise you on the best course of action based on your specific circumstances.

Are there any side effects associated with this formulation?

As with any medication, there may be side effects. If you experience any unusual symptoms or side effects, contact your healthcare provider immediately.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
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