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This formulation of Buprenorphine Hydrochloride 1.62 mg/ml Transdermal Gel is a semi-solid preparation that is dispensed through a pump mechanism. This design allows for easy and precise application on the skin, ensuring targeted treatment and efficient absorption of the active ingredients. The gel-like consistency of the formulation enhances its spreadability and adherence to the skin, promoting optimal drug delivery.
Buprenorphine Hydrochloride is a potent opioid analgesic that works by binding to the opioid receptors in the brain, spinal cord, and other areas of the body. It effectively blocks the transmission of pain signals, providing significant relief from moderate to severe pain. This makes it a valuable treatment option for various disease states associated with such pain levels.
As a transdermal gel, this formulation offers several advantages. It bypasses the gastrointestinal tract, eliminating the risk of oral side effects and improving patient compliance. The transdermal route also ensures a steady release of the medication over time, providing consistent pain relief without the need for frequent dosing. Furthermore, the pump mechanism allows for dose customization according to individual patient needs, enhancing the safety and efficacy of the treatment.
However, it's important to note that Buprenorphine Hydrochloride, like other opioids, carries a risk of addiction, abuse, and misuse, which can lead to overdose and death. Therefore, it should be used under the close supervision of a healthcare provider. Patients should be educated about the proper use of the medication, including the importance of using the pump mechanism correctly to avoid accidental overdose.
Prescribers should monitor patients regularly for signs of opioid addiction, abuse, or misuse. They should also consider other factors such as the patient's overall health status, the severity of the pain, and the patient's response to treatment when determining the appropriate dose. In addition, prescribers should be aware of potential drug interactions and contraindications associated with Buprenorphine Hydrochloride.
If you have any questions about this formulation of Buprenorphine Hydrochloride 1.62 mg/ml Transdermal Gel, please don't hesitate to reach out to us. Our team of compounding pharmacists at Bayview Pharmacy is always here to provide you with the information and support you need.
Buprenorphine Hydrochloride is a potent opioid analgesic that is used to manage severe pain that cannot be controlled by other medicines. It is also used as part of a comprehensive treatment program for drug abuse (e.g., compliance monitoring, counseling, behavioral contract, lifestyle changes). This medication is used to help relieve severe ongoing pain. Buprenorphine belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain.
Certain medications may affect how Buprenorphine Hydrochloride works or increase the risk of side effects. These include, but are not limited to, other opioid medications, certain antidepressants (e.g., SSRIs, SNRIs, TCAs), benzodiazepines, antipsychotics, certain antibiotics (e.g., erythromycin, clarithromycin), and certain antifungal medications (e.g., ketoconazole, itraconazole).
It is also important to note that Buprenorphine Hydrochloride can interact with certain substances such as alcohol and illicit drugs. These substances can increase the risk of serious side effects such as respiratory distress, coma, or even death. Therefore, it is crucial to avoid these substances while using Buprenorphine Hydrochloride.
Furthermore, certain medical conditions can affect the use of Buprenorphine Hydrochloride. These include, but are not limited to, respiratory problems (e.g., asthma, chronic obstructive pulmonary disease), liver disease, kidney disease, and certain mental health conditions (e.g., depression, psychosis). It is important to inform your healthcare provider of any existing medical conditions before starting treatment with Buprenorphine Hydrochloride.
Lastly, it is important to note that Buprenorphine Hydrochloride can cause physical dependence and withdrawal symptoms if stopped suddenly. Therefore, it is crucial to follow your healthcare provider's instructions when it comes to adjusting the dose or discontinuing the medication.
Remember, this is not a complete list of potential drug interactions or precautions. Always consult with your healthcare provider or pharmacist for personalized advice. If you have any questions or concerns, please do not hesitate to reach out to us at Bayview Pharmacy. We are here to help.
Buprenorphine Hydrochloride 1.62 mg/ml Transdermal Gel is a unique formulation designed to deliver the active ingredient, Buprenorphine Hydrochloride, directly through the skin. Buprenorphine is a potent opioid analgesic, which works by binding to the mu-opioid receptors in the brain and spinal cord. This binding action blocks the transmission of pain signals, providing relief from moderate to severe pain.
The transdermal gel formulation is designed to facilitate the slow and steady release of Buprenorphine into the bloodstream through the skin. The gel is applied topically to a clean, dry, and non-irritated area of the skin, typically on the upper arm or chest. The drug then penetrates the skin layers and enters the systemic circulation, providing pain relief over an extended period.
One of the key advantages of this formulation is its ease of use and precision in dosing. The pump mechanism allows for accurate dispensing of the medication, ensuring that the patient receives the correct dose. This is particularly beneficial for patients who may have difficulty swallowing tablets or capsules, or for those who require long-term pain management.
This formulation is used to treat various disease states that involve chronic pain. These include conditions like cancer pain, neuropathic pain, and chronic non-malignant pain. By providing steady and prolonged pain relief, Buprenorphine Hydrochloride 1.62 mg/ml Transdermal Gel can significantly improve the quality of life for patients suffering from these conditions.
Therefore, it's crucial that this medication is used under the supervision of a healthcare provider, and that the dosing instructions are followed carefully.
If you have any questions about Buprenorphine Hydrochloride 1.62 mg/ml Transdermal Gel, or if you need further information on how to use this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is always here to help.
This formulation of Buprenorphine Hydrochloride transdermal gel is traditionally administered for pain management, especially for chronic pain conditions. This includes conditions like fibromyalgia, neuropathic pain, and arthritis. However, it also bears utility in other applications beyond these mentioned disease states.
One such application is in opioid use disorder treatments. Buprenorphine is an opioid partial agonist which can aid in managing opioid withdrawal symptoms and cravings, substantially assisting in detoxification and maintenance phases of opioid dependency treatment. Given its transdermal mode of administration, it optimizes therapeutic benefits by maintaining a steady and long-lasting serum level of the drug.
Another novel use of buprenorphine is in managing refractory depression. Some recent studies have indicated potential anti-depressant properties of buprenorphine, especially when used in combinations with traditional anti-depressants. This could be particularly beneficial in individuals for whom standard treatments have proved unsuccessful.
Furthermore, this dosage form can also be employed for its anesthetic properties in minor surgical or procedural pain management where oral administration of analgesics might be inconvenient or undesirable.
However, the application of this formulation in regard to these additional uses remains contentious and is not universally accepted. It's important to emphasize that clinical presentation, patient history, comorbidities, and consultation with healthcare professionals should guide individualized treatment plans. It's crucial that prescribers and patients are aware of the potential risks associated with Buprenorphine use such as potential for addiction, abuse, misuse, life-threatening respiratory depression, accidental exposure, neonatal opioid withdrawal syndrome, and potential for production of adrenal insufficiency.
If you have any further questions about this formulation or any other drugs, please don't hesitate to reach out to us at Bayview Pharmacy. We strive to provide our patients with the most updated and comprehensive information about their medications.
This is a semi-solid compounded formulation that contains 1.62 mg/ml of Buprenorphine Hydrochloride. It's dispensed using a pump mechanism for easy and precise application on the skin. It's designed for targeted treatment and absorption of the active ingredient in a gel-like consistency.
The pump mechanism refers to the dispensing method of the transdermal gel. It ensures the accurate administration of the gel in controlled, consistent doses, thereby minimizing the risk of over or under-dosing.
You apply the gel to the skin following the dosage instruction provided by your healthcare provider. Make sure to wash and dry your hands and the application spot before using it to avoid contamination.
You should apply the gel to an area of the skin as directed by your healthcare provider. Avoid areas with open wounds, abrasions, or irritations as it may cause increased absorption and side effects.
This formulation is mainly used to manage pain when you need consistent delivery of medication.
The advantage of a transdermal gel is that it directly delivers medication to the affected area, thus providing targeted treatment. It's also easier to apply, less invasive than injections, and avoids the potential discomfort of oral ingestion.
If you miss a dose, you should apply it as soon as you remember. If it's almost time for the next dose, skip the missed one and continue with your regular schedule. Don't double up on a dose to make up for a missed one.
Just like any medication, Buprenorphine Hydrochloride 1.62 mg/ml Transdermal Gel may cause side effects. These can include skin irritation at the application site, dizziness, or constipation. Always consult your healthcare provider if you experience any unusual or persistent symptoms.
Yes, you can typically wear it while bathing or showering. However, heat and moisture may potentially enhance absorption so it's best to check with your healthcare provider.
Those with allergies to any of the ingredients, pregnant or breastfeeding women, and individuals with certain medical conditions shouldn't use the product. As always, consult your healthcare provider before starting any new medication.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.
This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NY, NJ, NH, FL, and ME. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
