Phenytoin 5%/Naltrexone HCl 1% Topical Gel
Phenytoin 5%/Naltrexone HCl 1% Topical Gel is a medication used to alleviate painful wounds and expedite wound healing. It combines the anticonvulsant phenytoin, which helps with pain relief, with the opioid antagonist naltrexone, which reduces inflammation and aids in tissue repair. This product is applied topically and can be left on the wound or washed off with water.
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Formula Information
Our unique formulation of Phenytoin 5%/Naltrexone HCl 1% Topical Gel is an effective and efficient way to treat Painful Wounds. This formulation contains two active ingredients: Phenytoin, an anticonvulsant, and Naltrexone HCl, an opioid antagonist. The phenytoin helps stop local transmission of painful impulses, while the naltrexone helps to reduce inflammation and pain. This combination helps to reduce inflammation, pain, and edema around the wound, promoting faster healing. Additionally, the gel is easy to apply and is designed to adhere to exposed skin so that it can readily penetrate and absorb into the wound. It should be applied once a day to the affected area, and can be covered with a bandage if required. Due to the unique combination of active ingredients, it is considered a safe and effective treatment for Painful Wounds. If you have any questions about using this formulation, please do not hesitate to reach out to us.
Drug Interactions
Phenytoin 5%/Naltrexone HCl 1% Topical Gel is a medication used to alleviate painful wounds and expedite wound healing. It combines the anticonvulsant phenytoin, which helps with pain relief, with the opioid antagonist naltrexone, which reduces inflammation and aids in tissue repair. This product is applied topically and can be left on the wound or washed off with water.
How Does it Work
Phenytoin 5%/Naltrexone HCl 1% Topical Gel is a combination product indicated for the management of wound healing and pain in wounds. Phenytoin is an antiepileptic drug that increases wound healing by increasing vascularization and promoting tissue regeneration. Naltrexone HCl is an opioid receptor antagonist with anti-hyperalgesic effects. It helps to reduce pain at the wound site by blocking the action of endogenous opioid peptides. The combination of these two drugs in the topical gel formulation provides a synergistic effect to reduce both wound healing time and associated pain. The topical gel is applied directly onto the wound site and allowed to air dry, forming a protective barrier. This barrier prevents further damage from external factors such as environmental influences, direct trauma, and bacterial or fungal contamination. This helps to reduce the risk of infection and promotes wound healing. In addition, the topical gel formulation is beneficial due to its ability to provide sustained drug release, allowing for improved wound healing and reduced pain over an extended period of time.
Other Uses
In addition to treating painful wounds, the compounded formulation of Phenytoin 5%/Naltrexone HCl 1% Topical Gel may be beneficial for managing various skin conditions, such as psoriasis and seborrheic dermatitis. Furthermore, this formulation can be used on burns and cuts in order to provide relief from itching and inflammation, and to reduce the risk of infection. Additionally, it has been known to be effective in treating itching caused by insect bites. As such, the compounded formulation of Phenytoin 5%/Naltrexone HCl 1% Topical Gel may provide relief from various skin conditions, and may be beneficial for a variety of dermatological issues.
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.