Estriol 0.05% Vaginal Gel
Estriol 0.05% Vaginal Gel is a prescription medication used to treat vaginal atrophy or vaginal dryness in women. It works by restoring natural hormone levels and thinning the vaginal lining to reduce pain, itching and burning. It is applied directly to the vaginal area using an applicator.
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Formula Information
Estriol 0.05% Vaginal Gel is a safe, effective, and well-tolerated hormone therapy treatment option for treating Women’s Health - Vaginal Atrophy/Vaginal Dryness. This product is a compounded preparation of estriol (E3) designed to help alleviate the symptoms associated with this menopause-related condition. Estriol is a naturally occurring endogenous estradiol metabolite that helps to restore the normal balance of hormones in the vagina. When applied locally, the gel is quickly and efficiently absorbed, restoring hydration and functioning of the vagina by increasing collagen content, elasticity, and thickness of the vaginal epithelium. Estriol has also been shown to reduce urinary tract infections as well as symptoms such as dryness and irritation. If you have any questions regarding the use of Estriol 0.05% Vaginal Gel for treating Women’s Health - Vaginal Atrophy/Vaginal Dryness, please contact us.
Drug Interactions
Estriol 0.05% Vaginal Gel is a prescription medication used to treat vaginal atrophy or vaginal dryness in women. It works by restoring natural hormone levels and thinning the vaginal lining to reduce pain, itching and burning. It is applied directly to the vaginal area using an applicator.
How Does it Work
Estriol 0.05% Vaginal Gel is a topical prescription medication used to treat the symptoms of Vaginal Atrophy, also known as Genitourinary Syndrome of Menopause, or GSM. Estriol 0.05% Vaginal Gel is a form of hormone therapy and contains the synthetic version of the hormone, estriol. Estriol is one of the three main estrogens naturally produced by the body, and is typically produced in higher levels during pregnancy.
When administered topically, estriol is absorbed through the lining of the vagina, and acts to restore the structure and integrity of the vaginal tissue. Estriol 0.05% Vaginal Gel replaces the hormones lost due to vaginal atrophy, and works to improve the health of the mucous membranes. Estriol can also affect the production of collagen and elastin proteins, providing a more elastic and healthy vaginal wall. Estriol 0.05% Vaginal Gel is effective in treating the symptoms of vaginal dryness and discomfort caused by vaginal atrophy.
Estriol 0.05% Vaginal Gel is typically used once daily for three to four weeks, followed by two to four weeks of maintenance therapy following the initial treatment. Patients should be monitored for response to the treatment and should report any changes to their physician. Prior to beginning treatment, it is important to discuss any potential risks and benefits with a healthcare provider.
Other Uses
Estriol 0.05% Vaginal Gel has the potential to be used for other pediatric and adult conditions. The compounded formulation of Estriol 0.05% Vaginal Gel could be used to treat vulvar pain caused by vulvodynia or burning due to stenosis of the vulvar vestibule. It could also be used to treat irritation and itching caused by vulvovaginal candidiasis (VVC). This compounded formulation of Estriol 0.05% Vaginal Gel may also be used in the treatment of menopausal women experiencing vasomotor symptoms, such as hot flashes and night sweats. The gel can be used in the treatment of lichen sclerosus, a skin condition that causes painful sores in the vaginal and vulvar area, including irritation and itching. Since Estriol 0.05% Vaginal Gel is a compounded formulation, it can be customized to the needs of each patient, depending on the severity of their symptoms.
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.