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Acne Treatments | Compounded Rx | Bayview Pharmacy

Acne Treatments

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Medically reviewed by Ryan Dyer, RPh
Last updated on
September 3, 2026
Starting at
$133
for
60 g
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Start with a prescription
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, NY, FL & ME
  • Hits three causes at once. Clogged pores, bacteria, and inflammation.
  • Built for your skin. Separate approaches for hormonal acne and adult acne.
  • Fades what acne leaves behind. Helps lighten post-acne dark marks.
  • One cream, not five. Replaces a layered routine of separate products.

A compounded acne treatment line of twelve topical creams spanning retinoids, antibiotics, benzoyl peroxide, azelaic acid, and topical spironolactone, selected and combined by your provider.

Bayview compounds prescription topical lines for rosacea and redness, melasma and dark spots, wrinkles and fine lines, and hair loss.

Which formula is right for me?

That's your provider's call. Different formulas target different drivers of acne, clogged pores, bacteria, inflammation, oil production, or post-acne dark marks, and your provider selects based on your skin, your acne pattern, and what you've already tried.

How long until my skin improves?

Most topical acne treatments need 4 to 6 weeks of consistent use before skin improves, and sometimes longer. Retinoid-containing formulas can make breakouts look temporarily worse in the first week or two before they get better, that's expected, so don't stop without talking to your provider.

Trusted by 105,826 patients to date.
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Compounded medications are prepared pursuant to a valid prescription for an individual patient and are not FDA-approved. This page is for educational purposes and is not medical advice.
**The FDA does not review or approve compounded medications for safety or effectiveness. A valid prescription from a licensed practitioner is required.
Important safety information →
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Getting your prescription filled is simple

Send us your prescription

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1
Have your provider e-prescribe to Bayview, fax it to us, or call it in directly to one of our pharmacists.
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A pharmacist reviews it

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We verify your prescription and prepare your medication to your provider's exact instructions.
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We compound & ship

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We prepare your medication and ship it discreetly to your door, with support when you need it.
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Understanding Acne

Acne is one of the most common skin conditions. Breakouts happen when hair follicles clog with oil and dead skin cells, allowing bacteria to grow and the surrounding skin to become inflamed. That can show up as blackheads, whiteheads, red pimples, or deeper, more painful bumps, most often on the face, chest, shoulders, and back. It is most common in teenagers, but many adults deal with it too, especially hormone-related breakouts in women.

Bayview Pharmacy prepares compounded, prescription-only acne creams that a provider can use as part of care for acne, tailored to the patient and to what is driving their breakouts. Bayview compounds this as part of our dermatology compounding line.

Why does acne happen?

Four things drive most acne: extra oil production, pores clogged with dead skin cells, bacteria that grow inside the clogged pore, and the inflammation that follows. Hormonal changes, during the teenage years, menstrual cycles, or times of stress, can turn oil production up, which is why breakouts often track with them. Genetics play a role as well, and even after a blemish heals, it can leave behind a dark mark that fades slowly. Adult breakouts that come with flushing and persistent facial redness may be rosacea, a different condition treated with different ingredients.

Because several different factors can be at work, treatments target different steps: unclogging pores, reducing bacteria, calming inflammation, or dialing down oil production. You can read more about the condition from MedlinePlus (NIH).

How Bayview treats acne

Rather than one ladder of strengths, this line is a toolkit of twelve compounded creams your provider can choose from based on what is driving your acne. Tretinoin, a retinoid, speeds skin cell turnover to keep pores from clogging (MedlinePlus, tretinoin topical). Clindamycin and erythromycin are antibiotics that slow the growth of acne-causing bacteria (MedlinePlus, clindamycin topical), and benzoyl peroxide works against those bacteria in a different way (MedlinePlus, benzoyl peroxide).

From there, the line covers more specific needs: azelaic acid both fights bacteria and reduces the keratin buildup that clogs pores (MedlinePlus, azelaic acid), spironolactone is compounded as a cream for hormone-related breakouts, sulfacetamide and sulfur offer an older but well-established combination, hydroquinone can be paired with an antibiotic to address post-acne dark marks, and niacinamide and sodium hyaluronate help calm and hydrate the skin. Many formulas combine two actives in one cream.

Our acne lineup

Twelve compounded creams spanning retinoids, antibiotics, benzoyl peroxide, azelaic acid, and a topical hormonal option, matched to what is driving your breakouts.

Compare the formulas

Why a personalized, compounded approach?

Commercial acne products come in fixed strengths and fixed pairings. Compounding lets a licensed pharmacy combine two actives in one cream, prepare concentrations that are not available off the shelf, and offer options, like a topical form of spironolactone, that are not commercially manufactured. That means your provider can match the formula to the type of acne you have, your skin's sensitivity, and what you have already tried, rather than a one-size product. As a 503A compounding pharmacy, Bayview prepares each order in small batches under USP <795> standards using quality ingredients. Related dermatology preparations include Rosacea & Redness, Melasma & Dark Spots, Wrinkles & Fine Lines, and Hair Loss. The full list is in our compounded medications catalog.

What to expect

Acne treatment takes patience. Most topical treatments need several weeks before skin improves, often 4 to 6 weeks and sometimes longer, and retinoid-based formulas can make breakouts look temporarily worse in the first week or two before they get better. Some dryness, redness, or peeling is common early on. Daily broad-spectrum sunscreen matters, since several of these actives increase sun sensitivity, and benzoyl peroxide can bleach fabrics and hair, so let it dry before it touches towels or pillowcases. Results vary from person to person, and your provider may adjust your formula over time.

What to know before you start

Which of these apply depends on which formula your provider chooses. These are the ones that come up most often.

  • Retinoid formulas can make things look worse before they look better. Redness, flaking, and a temporary flare in the first few weeks are expected as skin adjusts.
  • Wear broad-spectrum sunscreen every day. Several of these actives make skin more sensitive to sun.
  • Benzoyl peroxide bleaches fabric and hair. It will lighten towels, pillowcases, and clothing it touches. Use white linens, or let it dry fully first.
  • Tell your provider if you are allergic to sulfa drugs. The sulfacetamide formulas are not appropriate if you are.
  • Contact your provider if you develop persistent diarrhea while using a clindamycin formula. This is rare, but it is worth reporting rather than waiting out.
  • Formulas containing tretinoin, spironolactone, or hydroquinone should not be used in pregnancy or while breastfeeding. Tell your provider if any of this applies to you or changes during treatment.

How do I get started?

Because these are prescription formulas, a licensed provider decides whether treatment is appropriate and chooses the formula and strength for you. Bayview Pharmacy does not provide consultations or determine appropriateness, and a valid prescription is required. Once you have a prescription, your provider can order through Bayview, and a pharmacist is available if you have questions.

Clinical details for prescribers

Line overview. Twelve compounded topical creams addressing the principal pathogenic factors in acne vulgaris:

  • Follicular hyperkeratinization, tretinoin 0.025 to 0.05%, azelaic acid 5 to 15%
  • C. acnes proliferation, clindamycin 1 to 2%, erythromycin 2 to 3%, benzoyl peroxide 5 to 20%, sulfacetamide sodium 10%/sulfur 5%
  • Inflammation, azelaic acid, niacinamide 4%
  • Sebum production, spironolactone 5% (off-label compounded topical antiandrogen)

Combination rationale. Combination formulas pair an antibiotic with benzoyl peroxide or a retinoid, consistent with stewardship preferences against topical antibiotic monotherapy. Clindamycin 2%/hydroquinone 4% additionally addresses post-inflammatory hyperpigmentation.

Counseling points:

  • Retinization and transient flaring with retinoid formulas
  • Photosensitivity, daily broad-spectrum SPF
  • Fabric and hair bleaching with benzoyl peroxide
  • Sulfonamide hypersensitivity with sulfacetamide
  • Rare association of topical clindamycin with C. difficile colitis
  • Avoid tretinoin-, spironolactone-, and hydroquinone-containing formulas in pregnancy or lactation

Full formula options and safety information appear elsewhere on this page. Account setup, licensing, and ordering are covered on our for providers page.

This information is about a skin condition and its treatment options and is not medical advice. Compounded medications are prescription-only and are not FDA-approved. Your provider determines whether treatment is appropriate and sets the formulation and dose.

References

  1. MedlinePlus (NIH)
  2. MedlinePlus, tretinoin topical
  3. MedlinePlus, clindamycin topical
  4. MedlinePlus, benzoyl peroxide
  5. MedlinePlus, azelaic acid

Reviewed by Ryan Dyer, RPh, pharmacist at Bayview Pharmacy. Last reviewed July 7, 2026. Bayview does not provide consultations and does not decide whether a medication is right for you. Your prescriber makes that call.

In Stock
Acne Treatments, a compounded medication prepared by Bayview Pharmacy

On this page

Designed for acne-prone skin

Compounded acne creams are applied directly to breakout-prone areas. Your prescriber may select a combination of ingredients intended to address excess oil, clogged pores, bacteria, inflammation, and the dark marks breakouts can leave behind.

Start with a prescription
Compounded acne cream for breakout-prone skin

A formula matched to your breakouts

Each cream is compounded to the ingredients, strengths, and directions prescribed for you. With twelve formulas spanning retinoids, antibiotics, benzoyl peroxide, azelaic acid, and a topical hormonal option, your provider can match one to your skin and history.

View formula options
Compounded prescription acne cream prepared for one patient

Discreet, reliable delivery

Your medication ships in plain, secure packaging straight to your door, with clear instructions included. If you ever have a question, a Bayview pharmacist is always a phone call away.

Discreet, plain package delivered to a patient's door

Personalized compounding for patients who need more than a standard option.

"As a compounding pharmacy, we prepare each medication to a provider’s exact specifications. My focus, and my team’s focus, is quality, consistency, and close communication with prescribers so patients receive medication prepared for their individual needs."
Ryan Dyer, RPh
Owner and Chief Pharmacist, Bayview Pharmacy
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Three clear liquid vials, white powder on spoon, two capsules, and a cream jar on a metal surface.
QUALITY AND TESTING

Held to a higher standard

Every preparation is made under strict quality controls, and verified by a licensed pharmacist.
We use validated quality processes and third-party testing where appropriate
Sterile compounding in a dedicated USP <797> cleanroom
Non-sterile compounding under USP <795> and <800> standards
USP/NF-grade ingredients from reputable, vetted suppliers

Why patients choose Bayview

Trusted since 2006
Real pharmacist support
Quality tested
Made to your prescription
Made in our own pharmacy
Discreet, secure shipping

Our formulations

Each formula in this line is a topical cream built from one or two active ingredients that target different factors in acne. Your provider selects the preparation that is appropriate for you. Ingredient roles are described for education; concentrations are shown for reference.

Formula (topical cream) Ingredient roles
Azelaic acid 5% / Clindamycin 2%Dicarboxylic acid that helps unclog pores + antibiotic
Azelaic acid 15%Dicarboxylic acid; antibacterial, helps unclog pores, calms redness
Benzoyl peroxide 20%Antibacterial and pore-clearing agent
Clindamycin 1% / Benzoyl peroxide 5%Antibiotic + antibacterial, paired in one cream
Clindamycin 2% / Hydroquinone 4%Antibiotic + depigmenting agent for post-acne dark marks
Clindamycin 1% / Tretinoin 0.025%Antibiotic + retinoid that speeds skin cell turnover
Erythromycin 2%Macrolide antibiotic
Niacinamide 4%Form of vitamin B3 that helps calm skin
Sodium hyaluronate 0.1% / Tretinoin 0.05%Retinoid + humectant hydration to offset dryness
Spironolactone 5%Topical hormonal option compounded for hormone-related breakouts
Sulfacetamide sodium 10% / Sulfur 5%Sulfonamide antibacterial + keratolytic combination
Tretinoin 0.05% / Erythromycin 3%Retinoid + antibiotic, paired in one cream

Ingredients and concentrations are listed for education only and are not a statement that any formula is better, stronger, faster, or more effective. A valid prescription is required, and your provider determines which preparation is appropriate for you. These are compounded medications and are not FDA-approved.

Start with a prescription

Frequently asked questions

Which formula is right for me?

That's your provider's call. Different formulas target different drivers of acne, clogged pores, bacteria, inflammation, oil production, or post-acne dark marks, and your provider selects based on your skin, your acne pattern, and what you've already tried.

How long until my skin improves?

Most topical acne treatments need 4 to 6 weeks of consistent use before skin improves, and sometimes longer. Retinoid-containing formulas can make breakouts look temporarily worse in the first week or two before they get better, that's expected, so don't stop without talking to your provider.

What is topical spironolactone?

Spironolactone is a medication that counteracts the hormones that drive oil production. As a compounded 5% cream, it's an off-label topical option a provider may consider for hormone-related breakouts. It is not commercially manufactured as a cream, it's prepared by a compounding pharmacy.

Can I use these while pregnant or breastfeeding?

Several formulas, including those with tretinoin, spironolactone, or hydroquinone, are not recommended during pregnancy or while breastfeeding. Tell your provider if you are pregnant, planning to become pregnant, or breastfeeding so they can choose appropriately.

Will benzoyl peroxide bleach my clothes?

It can. Benzoyl peroxide bleaches fabric and hair on contact, including towels, pillowcases, shirt collars, and headbands. Let treated skin dry completely before dressing or lying down, wash your hands after applying, and consider switching to white towels and pillowcases while you use it.

Do I still need sunscreen?

Yes, every day. Tretinoin, benzoyl peroxide, and several other acne actives make skin more sun-sensitive, and sun exposure also darkens the marks breakouts leave behind. A broad-spectrum SPF 30 or higher each morning protects your results. A lightweight, non-comedogenic facial sunscreen works well alongside treatment.

What is compounding?

Compounding is the practice of preparing a medication tailored to an individual patient's prescription. Instead of a mass-produced product, a compounding pharmacy makes the medication to the specific strength, form, or combination your provider orders.

Examples on this site include medications compounded as liquids for people who cannot swallow pills, thyroid capsules made to a T3/T4 ratio no manufactured product offers, and all-purpose nipple ointment, which combines three actives that are not sold together commercially.

Do I need a prescription?

Yes. All of our medications require a valid prescription from a licensed provider. We're a dispensing and compounding pharmacy, so we don't provide consultations or write prescriptions. If you don't have one yet, you'll need to find and see a provider first.

Are compounded medications FDA-approved?

Compounded medications are not FDA-approved. They're prepared by a licensed pharmacy pursuant to a valid prescription for an individual patient, under USP standards. The FDA does not review compounded medications for safety or effectiveness.

Can you fill a prescription from my own provider?

Yes. Your provider can send your prescription to Bayview Pharmacy by e-prescribe, fax, or phone, or you can transfer an existing prescription from another pharmacy.

How do providers send a prescription to Bayview?

Providers can submit a prescription three ways:

  • E-prescribe: Search Bayview Pharmacy, Warwick, RI (NCPDP 4106882) in your EHR. For compounds, use the compound, custom, or free-text option and include the full formulation, strength, quantity, refills, and directions.
  • Fax: Send a signed order to 401-284-4506 (alt. 401-210-2757) with patient and prescriber details, medication, quantity, refills, directions, signature, and date.
  • Phone: Call 401-284-4505 to submit, clarify, or coordinate refills.

A valid prescription is required, and compounded medications are not FDA-approved.

How does shipping work?

Once your prescription is verified, we prepare your medication and ship it discreetly in plain packaging either via UPS or USPS. A pharmacy technician confirms the details with you before it goes out, and we're available if you have any questions.

How do refills and automatic refills work?

Refills are coordinated with your prescriber and your prescription. You can request a refill through our website or by calling us, and we'll handle the rest as long as you have refills remaining on a valid prescription. You can also opt into automatic refills on non-controlled substances, with no need to worry about running out of your medication. We can either ship it to you automatically, or ready for pickup.

Shipping & Delivery

Every prescription ships directly to your door in discreet packaging. Refrigerated medications travel in insulated coolers with ice packs to stay cold in transit.

Delivery AreaStandard ShippingRefrigerated Shipping
Rhode Island, Massachusetts & Connecticut$9 USPS$20 UPS
New Hampshire, New Jersey & New York$15 UPS$40 UPS Next Day Air
Florida$15 UPS$80 UPS Next Day Air

Need it faster? Expedited UPS is $15 for Rhode Island, Massachusetts and Connecticut. Your pharmacist will let you know if your medication needs refrigerated shipping. Questions? Call us at (401) 284-4505.

References

Sources reviewed

The medical information on this page draws on the following sources, which are also linked where cited.

  1. MedlinePlus (NIH). Acne.
  2. MedlinePlus (NIH). Tretinoin Topical.
  3. MedlinePlus (NIH). Clindamycin Topical.
  4. MedlinePlus (NIH). Benzoyl Peroxide Topical.
  5. MedlinePlus (NIH). Azelaic Acid Topical.

Important safety information

Do not use Acne Treatment if you:

  • Are allergic to any ingredient in your formulation, including sulfa (sulfonamide) medications for sulfacetamide-containing formulas and clindamycin or lincomycin for clindamycin-containing formulas.
  • Are pregnant, could become pregnant, or are breastfeeding; formulas containing tretinoin, spironolactone, or hydroquinone are not recommended.
  • Have a history of inflammatory bowel disease or antibiotic-associated colitis; tell your provider before using clindamycin-containing formulas.

Warnings and precautions:

  • For external use on the skin only. Avoid the eyes, lips, nostrils, and broken or sunburned skin.
  • Use exactly as directed by your provider, and do not exceed the dose or frequency they set.
  • Apply broad-spectrum sunscreen daily and limit sun exposure and tanning beds; several of these actives increase sun sensitivity.
  • Avoid other potentially irritating skin products (such as abrasive cleansers, alcohol-based astringents, or additional acne medications) unless your provider tells you otherwise.
  • Benzoyl peroxide can bleach hair, towels, clothing, and bedding; let treated skin dry fully before contact.
  • Use hydroquinone-containing formulas only as long as directed; prolonged use has rarely been linked to darkening of the skin.

Common side effects:

  • Dryness, redness, peeling, itching, or mild stinging, especially during the first weeks. Retinoid-containing formulas can make breakouts look temporarily worse before they improve. Your provider will review what to expect.

Get medical care if you have:

  • Severe irritation, blistering, or swelling of the treated skin.
  • Severe, watery, or bloody diarrhea or stomach cramps while using a clindamycin-containing formula; stop use and contact your provider.
  • Signs of a serious allergic reaction such as rash, hives, swelling of the face or throat, or trouble breathing.

Storage:

Store at room temperature away from heat, light, and moisture, do not freeze, and keep out of the reach of children. Discard as directed by your pharmacist.

This is a compounded prescription medication and is not approved by the FDA. Use it only under the supervision of a licensed provider, exactly as prescribed. Do not adjust your dose without talking to your prescriber. Seek emergency care for any severe or unexpected reaction. This information is not complete; talk to your provider about your full medical history and all medications you take.

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Send us your prescription and a Bayview pharmacist will take it from there.