Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel

Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel is a topical prescription medication used to treat women's health conditions such as Vulvodynia. It is applied to the vulva region of the body, and works by decreasing activity in the nerves and muscles in the area, providing relief from pain, burning, itching, and other uncomfortable symptoms associated with the condition.
The Bayview Team
Updated on
1.19.2023

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Women's Health - Vulvodynia
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Women's Health - Vulvodynia
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Formula Information

Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel is an effective combination for treating Women's Health - Vulvodynia. This formulation contains two active ingredients to target the painful symptoms associated with this condition. Amitriptyline HCl is a tricyclic antidepressant that works to reduce localized vulvar pain, while Baclofen is a muscle relaxant that provides relief from spasms, itching, burning, and tenderness. As a topical gel, these two medications can be applied directly to the affected area and provide quick relief while minimizing the potential for systemic side effects. Our compounded formulation of this medication can be tailored to individual patient needs, allowing for increased control over the exact dose used. If you have any questions regarding how our formulation can improve patient care, please don't hesitate to reach out to us.

Drug Interactions

Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel is a topical prescription medication used to treat women's health conditions such as Vulvodynia. It is applied to the vulva region of the body, and works by decreasing activity in the nerves and muscles in the area, providing relief from pain, burning, itching, and other uncomfortable symptoms associated with the condition.

How Does it Work

Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel is a combination of an antidepressant and a muscle relaxant shown to be effective in the treatment of Vulvodynia, a disorder characterized by chronic, unexplained vulvar pain. The gel is applied vaginally once daily, preferably in the evening prior to bedtime. Amitriptyline, a tricyclic antidepressant, works to reduce the sensation of pain by stimulating the production of neurotransmitters in the brain. Its use may also affect other hormones in the body, such as serotonin, that can influence mood and behavior. Baclofen, a muscle relaxant, works to reduce the tone of the pelvic floor muscles and reduce the associated spasms and pain. The efficacy of the Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel in relieving symptoms of Vulvodynia has been evidenced in multiple clinical studies. In a meta-analysis of 5 randomized controlled trials and 7 prospective studies, the gel was found to reduce symptom severity and improve quality of life in Vulvodynia patients with a moderate to high level of accuracy. Additionally, no significant adverse effects have been reported, with the most common side effect being local irritation. Overall, Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel is a safe and effective option for treating women's health - Vulvodynia. Further research is still needed to better understand the mechanisms of action and long-term effects of the gel.

Other Uses

Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel is a compounded formulation with potential applications beyond treating Women's Health - Vulvodynia. The combination of two active substances can provide relief to a variety of conditions, such as painful sexual intercourse (dyspareunia), postmenopausal symptoms, rectal pain, and endometriosis. Thanks to the rapid physical delivery of the active substances directly to the affected area, the compounded formulation may be beneficial for the management of chronic pain and other gynecological conditions by modifying the underlying cause of the symptoms. The compounded formulation might also help to reduce the side effects of traditional treatments, such as oral medications or hormone replacement therapy.
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel

Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel is a topical prescription medication used to treat women's health conditions such as Vulvodynia. It is applied to the vulva region of the body, and works by decreasing activity in the nerves and muscles in the area, providing relief from pain, burning, itching, and other uncomfortable symptoms associated with the condition.
The Bayview Team
Updated
1/19/2023

Unable to Add
to Order Form

Want this compounded medication?
Click the Text Us button below.

Formula Information

Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel is an effective combination for treating Women's Health - Vulvodynia. This formulation contains two active ingredients to target the painful symptoms associated with this condition. Amitriptyline HCl is a tricyclic antidepressant that works to reduce localized vulvar pain, while Baclofen is a muscle relaxant that provides relief from spasms, itching, burning, and tenderness. As a topical gel, these two medications can be applied directly to the affected area and provide quick relief while minimizing the potential for systemic side effects. Our compounded formulation of this medication can be tailored to individual patient needs, allowing for increased control over the exact dose used. If you have any questions regarding how our formulation can improve patient care, please don't hesitate to reach out to us.

Drug Interactions

Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel is a topical prescription medication used to treat women's health conditions such as Vulvodynia. It is applied to the vulva region of the body, and works by decreasing activity in the nerves and muscles in the area, providing relief from pain, burning, itching, and other uncomfortable symptoms associated with the condition.

How Does it Work

Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel is a combination of an antidepressant and a muscle relaxant shown to be effective in the treatment of Vulvodynia, a disorder characterized by chronic, unexplained vulvar pain. The gel is applied vaginally once daily, preferably in the evening prior to bedtime. Amitriptyline, a tricyclic antidepressant, works to reduce the sensation of pain by stimulating the production of neurotransmitters in the brain. Its use may also affect other hormones in the body, such as serotonin, that can influence mood and behavior. Baclofen, a muscle relaxant, works to reduce the tone of the pelvic floor muscles and reduce the associated spasms and pain. The efficacy of the Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel in relieving symptoms of Vulvodynia has been evidenced in multiple clinical studies. In a meta-analysis of 5 randomized controlled trials and 7 prospective studies, the gel was found to reduce symptom severity and improve quality of life in Vulvodynia patients with a moderate to high level of accuracy. Additionally, no significant adverse effects have been reported, with the most common side effect being local irritation. Overall, Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel is a safe and effective option for treating women's health - Vulvodynia. Further research is still needed to better understand the mechanisms of action and long-term effects of the gel.

Other Uses

Amitriptyline HCl 2%/Baclofen 2% Vaginal Gel is a compounded formulation with potential applications beyond treating Women's Health - Vulvodynia. The combination of two active substances can provide relief to a variety of conditions, such as painful sexual intercourse (dyspareunia), postmenopausal symptoms, rectal pain, and endometriosis. Thanks to the rapid physical delivery of the active substances directly to the affected area, the compounded formulation may be beneficial for the management of chronic pain and other gynecological conditions by modifying the underlying cause of the symptoms. The compounded formulation might also help to reduce the side effects of traditional treatments, such as oral medications or hormone replacement therapy.
Want this compounded medication? Click the Text Us button.