Ketamine HCl 0.5% / Diazepam 1% / Baclofen 2% Vaginal Gel

Ketamine HCl 0.5%/ Diazepam 1%/ Baclofen 2% Vaginal Gel is an anesthetic medication used to treat vulvodynia, a condition in women marked by chronic vulvar discomfort. The combination of these three drugs in this cervical gel provides a synergistic effect that helps reduce pain and inflammation associated with vulvodynia.
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Formula Information

Ketamine HCl 0.5% / Diazepam 1% / Baclofen 2% Vaginal Gel is a compounded formulation designed to treat Women's Health - Vulvodynia. This formulation is tailored to target the symptoms of Vulvodynia, and is designed to provide physicians and patients with an effective and safe therapeutic alternative. Ketamine HCl 0.5% is an NMDA receptor antagonist that helps reduce pain, while Diazepam 1% is an anxiolytic that reduces muscle spasms and reduces physical arousal related to pain. Lastly, Baclofen 2% is a GABA-B agonist that reduces nerve pain and improves nerve function by decreasing the excitability of muscles. Through the combined effects of these medications, the patient can experience significant reduction of the symptomatology associated with Vulvodynia. If you have any questions or wish to learn more about this formulation of Ketamine HCl 0.5% / Diazepam 1% / Baclofen 2% Vaginal Gel, please do not hesitate to reach out to us.

Drug Interactions

Ketamine HCl 0.5%/ Diazepam 1%/ Baclofen 2% Vaginal Gel is an anesthetic medication used to treat vulvodynia, a condition in women marked by chronic vulvar discomfort. The combination of these three drugs in this cervical gel provides a synergistic effect that helps reduce pain and inflammation associated with vulvodynia.

How Does it Work

Ketamine HCl 0.5%/Diazepam 1%/Baclofen 2% vaginal gel is an effective treatment for women's health-vulvodynia. This combination therapy is designed to provide local relief of vulvodynia symptoms, as well as to reduce neurogenic inflammation. Specifically, ketamine is an NMDA receptor antagonist, and is thought to modify neurogenic inflammation and reduce pain transmission. Diazepam is a benzodiazepine, which has been shown to provide muscle relaxation, reducing pelvic floor tension and pain. Lastly, baclofen has the ability to modulate spinal cord excitability, promoting a calming effect and reducing pain. Thus, this combination vaginal gel allows for local delivery of these medications, providing a more tailored and localized treatment for vulvodynia. Although the exact efficacy and duration of relief is still being studied, it has been demonstrated to provide relief in a small clinical study. As such, this combination therapy offers a promising solution for women suffering from vulvodynia.

Other Uses

This compounded formulation of Ketamine HCl 0.5% / Diazepam 1% / Baclofen 2% Vaginal Gel could potentially be used as an alternative to oral medications when traditional therapies such as non-steroidal anti-inflammatory drugs, calcium channel blockers, and tricyclic antidepressants are not effective in treating patients with chronic pelvic pain. The gel form may allow for the medicine to reach the site of need more rapidly, while avoiding the potential side effects associated with systemic therapies. Additionally, the topical administration of the medication may be more comfortable and convenient for the patient. Further research is necessary to evaluate the efficacy of this compounded formulation and its potential as an innovative alternative treatment option for chronic pelvic pain.
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

Ketamine HCl 0.5% / Diazepam 1% / Baclofen 2% Vaginal Gel

Ketamine HCl 0.5%/ Diazepam 1%/ Baclofen 2% Vaginal Gel is an anesthetic medication used to treat vulvodynia, a condition in women marked by chronic vulvar discomfort. The combination of these three drugs in this cervical gel provides a synergistic effect that helps reduce pain and inflammation associated with vulvodynia.

Formula Information

Ketamine HCl 0.5% / Diazepam 1% / Baclofen 2% Vaginal Gel is a compounded formulation designed to treat Women's Health - Vulvodynia. This formulation is tailored to target the symptoms of Vulvodynia, and is designed to provide physicians and patients with an effective and safe therapeutic alternative. Ketamine HCl 0.5% is an NMDA receptor antagonist that helps reduce pain, while Diazepam 1% is an anxiolytic that reduces muscle spasms and reduces physical arousal related to pain. Lastly, Baclofen 2% is a GABA-B agonist that reduces nerve pain and improves nerve function by decreasing the excitability of muscles. Through the combined effects of these medications, the patient can experience significant reduction of the symptomatology associated with Vulvodynia. If you have any questions or wish to learn more about this formulation of Ketamine HCl 0.5% / Diazepam 1% / Baclofen 2% Vaginal Gel, please do not hesitate to reach out to us.

Drug Interactions

Ketamine HCl 0.5%/ Diazepam 1%/ Baclofen 2% Vaginal Gel is an anesthetic medication used to treat vulvodynia, a condition in women marked by chronic vulvar discomfort. The combination of these three drugs in this cervical gel provides a synergistic effect that helps reduce pain and inflammation associated with vulvodynia.

How Does it Work

Ketamine HCl 0.5%/Diazepam 1%/Baclofen 2% vaginal gel is an effective treatment for women's health-vulvodynia. This combination therapy is designed to provide local relief of vulvodynia symptoms, as well as to reduce neurogenic inflammation. Specifically, ketamine is an NMDA receptor antagonist, and is thought to modify neurogenic inflammation and reduce pain transmission. Diazepam is a benzodiazepine, which has been shown to provide muscle relaxation, reducing pelvic floor tension and pain. Lastly, baclofen has the ability to modulate spinal cord excitability, promoting a calming effect and reducing pain. Thus, this combination vaginal gel allows for local delivery of these medications, providing a more tailored and localized treatment for vulvodynia. Although the exact efficacy and duration of relief is still being studied, it has been demonstrated to provide relief in a small clinical study. As such, this combination therapy offers a promising solution for women suffering from vulvodynia.

Other Uses

This compounded formulation of Ketamine HCl 0.5% / Diazepam 1% / Baclofen 2% Vaginal Gel could potentially be used as an alternative to oral medications when traditional therapies such as non-steroidal anti-inflammatory drugs, calcium channel blockers, and tricyclic antidepressants are not effective in treating patients with chronic pelvic pain. The gel form may allow for the medicine to reach the site of need more rapidly, while avoiding the potential side effects associated with systemic therapies. Additionally, the topical administration of the medication may be more comfortable and convenient for the patient. Further research is necessary to evaluate the efficacy of this compounded formulation and its potential as an innovative alternative treatment option for chronic pelvic pain.
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