Kojic Acid is a naturally occurring compound derived from fungi, renowned for its skin-lightening and depigmenting properties.
Kojic acid is a naturally occurring compound produced by fungi of the Aspergillus genus, particularly Aspergillus oryzae, and is used as a skin-lightening ingredient.[1] It works by chelating copper at the active site of tyrosinase, the enzyme involved in producing melanin, the pigment responsible for skin color.[1] It has been used in the treatment of hyperpigmentation disorders such as freckles, age spots, postinflammatory hyperpigmentation, and melasma.[1][3]
Kojic acid has also shown antioxidant properties in laboratory studies.[1] It is used in many cosmetic creams at lower concentrations, and at concentrations of 2% to 5% it is considered a cosmeceutical.[2] Bayview Pharmacy compounds kojic acid preparations on a prescriber's order.
Reported drawbacks of kojic acid include contact dermatitis and possible photodamage of the skin, so prescribers should consider skin sensitivity.[1] In clinical studies for melasma, kojic acid has been combined with other agents such as glycolic acid and hydroquinone.[1]
Each of these is compounded to order at our pharmacy and requires a prescription.
A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.
Other salt forms of this molecule, and ingredients commonly compounded alongside it.
This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.
Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.
Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.