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Active pharmaceutical ingredient

Niacinamide

Niacinamide, also known as nicotinamide, is a versatile and essential form of vitamin B3 that plays a crucial role in various biochemical processes within the body.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Niacinamide, also known as nicotinamide, is a form of vitamin B3 that plays a crucial role in various biochemical processes within the body. It is a water-soluble vitamin that is essential for maintaining healthy skin, supporting cellular energy production, and enhancing the function of the nervous system. Niacinamide is often utilized in compounded formulations due to its versatile therapeutic properties and its ability to address a wide range of dermatological and systemic conditions.

In dermatology, niacinamide is renowned for its anti-inflammatory and antioxidant effects, making it a popular choice for treating acne, rosacea, and hyperpigmentation. It helps to regulate sebum production, improve skin barrier function, and reduce the appearance of fine lines and wrinkles. Additionally, niacinamide can enhance the skin's natural defense mechanisms, providing protection against environmental stressors and UV damage.

Beyond its dermatological benefits, niacinamide is also used in formulations aimed at supporting overall health. It plays a vital role in the synthesis of NAD+ (nicotinamide adenine dinucleotide), a coenzyme involved in cellular metabolism and energy production. This makes niacinamide an important component in formulations designed to boost energy levels, support cognitive function, and promote healthy aging.

Niacinamide is well-tolerated by most individuals and is considered safe for use in various concentrations. Its inclusion in compounded formulations allows for tailored therapeutic approaches, enabling healthcare providers to address specific patient needs effectively. As a versatile and potent active ingredient, niacinamide continues to be a valuable asset in both dermatological and systemic health applications.

Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

Do niacinamide and hyaluronic acid make it work better?

We do not claim that. Tretinoin is the ingredient with decades of evidence behind it; niacinamide and sodium hyaluronate are supporting ingredients included with the aim of making a retinoid easier to tolerate. This three-ingredient combination has not been studied in controlled trials.

The niacinamide here is 2%, below the 4% concentration studied for acne on its own.

Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.