Isoniazid is a potent antibiotic primarily used in the treatment and prevention of tuberculosis (TB).
Isoniazid is a potent antibiotic primarily used in the treatment and prevention of tuberculosis (TB). It works by inhibiting the synthesis of mycolic acids, essential components of the mycobacterial cell wall, thereby exerting its bactericidal effects against actively dividing Mycobacterium tuberculosis.
As a first-line agent in TB therapy, isoniazid is often included in combination regimens to enhance efficacy and prevent the development of drug resistance. Its role in latent TB infection treatment is crucial, as it significantly reduces the risk of progression to active disease.
Prescribers should be aware of isoniazid's potential side effects, including hepatotoxicity and peripheral neuropathy, which necessitate regular monitoring of liver function and the possible co-administration of pyridoxine (vitamin B6) to mitigate neuropathic effects. Isoniazid's pharmacokinetics can be influenced by genetic factors, such as acetylator status, which may affect dosing and risk of adverse effects.
In compounding formulations, isoniazid can be tailored to meet specific patient needs, offering flexibility in dosing and administration routes. This customization is particularly beneficial for patients with unique therapeutic requirements or those who experience difficulties with standard treatment regimens.
Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.
We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.
Prescriber sign inA sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.
Other salt forms of this molecule, and ingredients commonly compounded alongside it.
This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.
Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.
Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.