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Active pharmaceutical ingredient

Levofloxacin Hydrochloride

Levofloxacin Hydrochloride is a potent fluoroquinolone antibiotic widely utilized in compounded formulations for its broad-spectrum antibacterial properties.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Levofloxacin Hydrochloride is a potent fluoroquinolone antibiotic widely utilized in compounded formulations for its broad-spectrum antibacterial properties. It is effective against a variety of gram-positive and gram-negative bacteria, making it a versatile choice for treating infections. This API works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication, transcription, repair, and recombination, ultimately leading to bacterial cell death.

Levofloxacin Hydrochloride is often prescribed for respiratory tract infections, urinary tract infections, and skin infections, among others. Its pharmacokinetic profile allows for excellent tissue penetration, which enhances its efficacy in treating deep-seated infections. The compound is well-absorbed orally, with a bioavailability of nearly 100%, allowing for flexible dosing regimens that can be tailored to the patient's needs.

In the context of compounding, Levofloxacin Hydrochloride can be formulated into various dosage forms, including oral suspensions, topical solutions, and ophthalmic preparations. This flexibility is particularly beneficial for patients who require customized treatment plans, such as those with specific allergies or intolerances to standard formulations. Additionally, the stability of Levofloxacin Hydrochloride in compounded formulations ensures that it maintains its efficacy throughout the treatment period.

Prescribers should be aware of potential side effects, which may include gastrointestinal disturbances, CNS effects, and hypersensitivity reactions. It is crucial to consider patient-specific factors, such as renal function, when determining the appropriate dosage to minimize the risk of adverse effects. Levofloxacin Hydrochloride's interaction profile should also be reviewed, as it may interact with other medications, including antacids and certain antiarrhythmic agents.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.