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Active pharmaceutical ingredient

Sulfamethoxazole

Sulfamethoxazole is a potent antibacterial agent commonly used in compounded formulations to treat a variety of bacterial infections.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Sulfamethoxazole is a synthetic antibacterial agent belonging to the class of sulfonamides, which are widely used in the treatment of bacterial infections. It functions by inhibiting the bacterial synthesis of dihydrofolic acid, a crucial component in the production of nucleic acids and proteins, thereby exerting a bacteriostatic effect. This mechanism of action makes sulfamethoxazole effective against a broad spectrum of gram-positive and gram-negative bacteria, making it a versatile choice in various compounded formulations.

In clinical practice, sulfamethoxazole is often combined with trimethoprim, another antibiotic, to enhance its efficacy through a synergistic effect. This combination is particularly effective in treating urinary tract infections, respiratory infections, and certain types of gastrointestinal infections. The pharmacokinetics of sulfamethoxazole involve rapid absorption from the gastrointestinal tract, with peak plasma concentrations typically reached within 1 to 4 hours after administration. It is primarily metabolized in the liver and excreted via the kidneys, necessitating dose adjustments in patients with renal impairment.

Prescribers should be aware of potential side effects associated with sulfamethoxazole, which can include hypersensitivity reactions, gastrointestinal disturbances, and hematological changes. It is crucial to assess patient history for any known allergies to sulfonamides before prescribing. Additionally, sulfamethoxazole may interact with other medications, such as anticoagulants and certain diuretics, which can enhance the risk of adverse effects. Monitoring patient response and adjusting dosages accordingly can help mitigate these risks and ensure optimal therapeutic outcomes.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.