The Acetaminophen 130 mg/Codeine Phosphate 13 mg Rectal Suppository is a solid dosage form designed for insertion into the rectum. Upon insertion, the suppository dissolves or melts, releasing the active ingredients, Acetaminophen and Codeine Phosphate, for local or systemic absorption. This formulation is typically used to treat conditions that require pain management, such as post-surgical pain, injury-related pain, and chronic conditions like cancer. It can also be used to manage symptoms of diseases that cause discomfort or pain, such as arthritis or fibromyalgia.

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
This formulation is a rectal suppository containing Acetaminophen 130 mg and Codeine Phosphate 13 mg. Acetaminophen is a pain reliever and a fever reducer, while Codeine Phosphate is a narcotic pain reliever. The suppository form allows for the medication to be absorbed directly into the bloodstream through the rectal tissue, providing faster relief than oral administration.
Acetaminophen works by changing the way the body senses pain and by cooling the body. Codeine, on the other hand, works in the brain to change how your body feels and responds to pain. This combination medication is typically used to relieve pain, coughing, and fever associated with conditions such as influenza, common cold, or after surgery or dental procedures. It may also be used for other conditions as determined by your healthcare provider.
It's important to note that this medication should be used only as directed by your healthcare provider. Overuse or misuse can lead to addiction, overdose, or death, especially in a child or other person using the medicine without a prescription. Also, while using this product, do not use any other drug containing acetaminophen without asking your doctor or pharmacist first. Acetaminophen is in many nonprescription and prescription medications (such as pain/fever drugs or cough-and-cold products). Too much acetaminophen may cause liver damage.
Patients should also be aware of potential side effects, which may include dizziness, lightheadedness, nausea, vomiting, shortness of breath, and sweating. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To prevent constipation, eat dietary fiber, drink enough water, and exercise. You may also need to take a laxative. Ask your pharmacist which type of laxative is right for you.
For prescribers, it's important to consider the patient's overall health status, other medications they may be taking, and their history of drug use or addiction. This medication should be prescribed with caution in patients with a history of drug abuse or addiction, as it can be habit-forming. Regular monitoring of the patient's response to the medication and any potential side effects is recommended.
If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.
The combination of Acetaminophen and Codeine Phosphate in a rectal suppository form is used to relieve moderate to severe pain. Acetaminophen is a non-opioid pain reliever that works by increasing the pain threshold, while Codeine Phosphate is an opioid pain reliever that works by changing the way the brain and nervous system respond to pain.
It's important to be aware of potential drug interactions when using this formulation. Certain medications may affect how Acetaminophen and Codeine Phosphate work or increase your risk for serious side effects.
Some drugs that may interact with this formulation include: other opioid pain or cough relievers (such as morphine, hydrocodone), alcohol, marijuana, drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).
Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness or increase the risk of liver damage. Ask your pharmacist about using those products safely.
Other medications can affect the removal of codeine/acetaminophen from your body, which may affect how this product works. Examples include azole antifungals (such as ketoconazole), macrolide antibiotics (such as erythromycin), HIV medications (such as ritonavir), rifamycins (such as rifabutin, rifampin), certain drugs used to treat seizures (such as carbamazepine, phenytoin), among others.
This medication may interfere with certain laboratory tests (including amylase/lipase levels), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.
Do not start, stop, or change the dosage of any medicines without your doctor's approval. A product that may interact with this drug is: metoclopramide.
Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. If you have any questions or concerns about this medication, please reach out to us at Bayview Pharmacy. We are here to help.
The Acetaminophen 130 mg/Codeine Phosphate 13 mg Rectal Suppository is a solid dosage form that is designed to be inserted into the rectum. Once inserted, the suppository dissolves or melts due to the body's natural heat, releasing the active ingredients, Acetaminophen and Codeine Phosphate, into the surrounding tissues.
Acetaminophen, also known as Paracetamol, is a common over-the-counter medication used to relieve pain and reduce fever. It works by inhibiting the production of prostaglandins, substances in the body that cause pain and inflammation. By reducing the levels of these substances, Acetaminophen can effectively alleviate pain and lower fever.
Codeine Phosphate, on the other hand, is an opioid analgesic. It works by binding to opioid receptors in the brain and spinal cord, blocking the transmission of pain signals to the brain. This results in a decrease in the perception of pain.
The combination of Acetaminophen and Codeine Phosphate in this suppository formulation provides a dual-action approach to pain management. While Acetaminophen works to reduce pain at the source, Codeine Phosphate alters the perception of pain at the central nervous system level.
Furthermore, the rectal administration route offers several advantages. It allows for medication to be administered when oral intake is not possible or desirable, such as in cases of nausea or vomiting. It also bypasses the first-pass metabolism in the liver, which can lead to a more rapid and efficient absorption of the medication. This can result in quicker onset of pain relief.
This formulation can be used to treat various disease states that involve pain and inflammation, such as post-surgical pain, cancer pain, and pain from injuries. It can also be used to manage conditions with intermittent or chronic pain, such as arthritis or fibromyalgia.
As with any medication, it is important to use this formulation as directed by a healthcare provider. Potential side effects can include constipation, nausea, dizziness, and drowsiness. It is also important to note that Codeine Phosphate has the potential for addiction and should be used with caution.
If you have any questions about the Acetaminophen 130 mg/Codeine Phosphate 13 mg Rectal Suppository, or if you would like more information about its use and potential side effects, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.
This is a compounded medication crafted in a solid dosage form for insertion into a body cavity, typically the rectum. Once inserted, it dissolves or melts, releasing the medication for local or systemic absorption.
The medication is absorbed faster and more efficiently in the rectal area.
Acetaminophen is a pain reliever and a fever reducer. It is commonly used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers.
Codeine Phosphate is a narcotic pain reliever (opiate-type) that acts on certain centers in the brain to give you pain relief.
Yes, potential side effects may include nausea, vomiting, constipation, lightheadedness, dizziness, drowsiness, sweating, or trouble sleeping. If you experience persistent or worsening symptoms, contact your healthcare provider immediately.
This medication should be stored at room temperature, away from light and moisture. Do not store in the bathroom and keep it away from children and pets.
This medication may cause drowsiness or dizziness, therefore, it is advised not to drive, use machinery, or do any activity that requires alertness until you can do it safely.
Consuming alcohol may increase your risk of liver damage or may enhance the side effects of drowsiness, dizziness, or lightheadedness. It is advised to avoid alcohol while on this medication.
If you miss a dose, use it as soon as you remember. If it's near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
You should consult with your healthcare provider before using this medication if you are pregnant or breastfeeding. The medication may have potential risks that your healthcare provider needs to consider against the potential benefits.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Insert 1 unwrapped suppository