
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Prepared to a prescriber's order for one patient. Not FDA-approved.
Acetaminophen is a non-opioid analgesic and fever reducer that compounding pharmacies prepare as rectal suppositories, oral suspensions and capsules in strengths not manufactured, by prescription.
Acetaminophen (paracetamol, APAP) is a non-opioid pain reliever and fever reducer. Its exact mechanism is not settled; it is thought to act mainly in the central nervous system rather than at the site of pain. Manufactured products are abundant: over-the-counter tablets, chewables, capsules, liquids and extended-release tablets (Tylenol and many others) and rectal suppositories (FeverAll, an NDA product sold over the counter) for temporary relief of minor aches, pains, headache and fever; and prescription acetaminophen injection (Ofirmev and generics), FDA-approved for mild to moderate pain in adults and children two and older, moderate to severe pain with adjunctive opioids, and fever. Suppositories are manufactured in only a few fixed strengths, so a prescriber might order compounded acetaminophen as a suppository in a strength not manufactured, as a combination suppository, or as a dye-free or sugar-free oral liquid. Compounded preparations are not FDA-approved and require a prescription.
The prescription intravenous product carries an FDA boxed warning for risk of medication errors and hepatotoxicity: acetaminophen has caused acute liver failure, at times resulting in liver transplant and death, most often from doses above the recommended maximum or more than one acetaminophen product at a time. Over-the-counter oral and rectal products carry the same message as a Drug Facts liver warning: severe liver damage may occur if you take more than the daily maximum, use other acetaminophen products at the same time, or have three or more alcoholic drinks a day. Do not use it if you are allergic to acetaminophen; rare but serious skin reactions and anaphylaxis have occurred, so stop at the first sign of rash. The injection is contraindicated in severe liver disease; ask your prescriber before any use if you have liver disease or take warfarin. The label and Drugs.com's breastfeeding monograph, citing primary studies, report low milk levels with rare infant effects. In September 2025 FDA noted studies associating use in pregnancy with autism and ADHD without evidence of causation; discuss pregnancy use with your prescriber. If side effects bother you, talk to your prescriber or pharmacist.
Acetaminophen's analgesic and antipyretic mechanism is not established and is thought to be predominantly central. Protein binding is low, about 10 to 25 percent; the mean half-life is about 2.4 hours in adults and 3 hours in children; metabolism is hepatic by glucuronidation, sulfation and CYP2E1 oxidation to the reactive intermediate NAPQI, detoxified by glutathione at therapeutic exposures. Rectal absorption is slower and more variable than oral, differs between suppository formulations, and requires larger doses to reach a given concentration; a 24-hour pediatric pharmacokinetic study found large interindividual variability and no accumulation with repeat rectal dosing (Birmingham et al., Anesthesiology 2001). Labeled indications: acetaminophen injection for mild to moderate pain in patients two and older, moderate to severe pain with adjunctive opioids, and fever; OTC oral and rectal products for minor aches, pains, headache and fever. Prescribers have ordered compounded acetaminophen suppositories in strengths and combinations not manufactured for patients who cannot take oral medication; the pediatric study notes that dose recommendations do not transfer between suppository formulations. Dosing and strength are per prescriber, counting total daily acetaminophen from all sources. Monitor hepatic function in hepatic impairment, alcoholism, malnutrition or severe renal impairment, and INR with chronic use in warfarin patients. Not a controlled substance.
Wash your hands. Apply the amount on your label to clean, dry skin and rub it in gently. For a metered pump, each press delivers a set amount; your label states how many presses. For transdermal creams, apply to the area your label names and let it dry before dressing. Wash your hands afterward and avoid skin-to-skin contact with others at the application site until it has absorbed. Do not apply to broken skin unless told to.
Creams are aqueous. Under USP <795>, a preserved cream usually carries a beyond-use date of up to 35 days at room temperature or refrigerated, and an unpreserved one 14 days refrigerated. Follow the storage line on your label, keep from freezing, keep out of reach of children, and discard after the beyond-use date.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)