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Acyclovir 5%/Hydrocortisone Acetate 1% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Acyclovir
Hydrocortisone Acetate

This gel combines the antiviral properties of Acyclovir with the anti-inflammatory effects of Hydrocortisone Acetate, providing relief from symptoms such as pain, itching, and swelling.

Dispensed through a pump mechanism, this formulation ensures easy and precise application, allowing for targeted treatment and optimal absorption of active ingredients. Its gel-like consistency facilitates smooth application on the skin, enhancing patient comfort and compliance.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Get a one-page sheet with everything your doctor needs to prescribe this and send it to Bayview.

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Acyclovir
Hydrocortisone Acetate
Topical Gel
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Currently licensed Limited basis, registration pending Not available for this formula Not currently licensed

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Formula Information

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Drug Interactions

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Acyclovir 5%/Hydrocortisone Acetate 1% Topical Gel is a compounded formulation designed to provide targeted treatment for conditions such as herpes simplex virus infections, including cold sores and genital herpes, as well as inflammatory skin conditions that may benefit from the anti-inflammatory properties of hydrocortisone. The combination of acyclovir, an antiviral agent, and hydrocortisone, a corticosteroid, aims to reduce viral replication and alleviate inflammation, respectively, thereby offering a dual-action approach to managing symptoms and promoting healing.

When considering the use of Acyclovir 5%/Hydrocortisone Acetate 1% Topical Gel, it is important to be aware of potential drug interactions that may affect the efficacy and safety of the treatment. Although topical formulations generally have a lower risk of systemic interactions compared to oral medications, certain considerations should still be taken into account. Patients using other topical medications on the same area of skin should consult with their healthcare provider to avoid potential interactions that could alter the absorption or effectiveness of the active ingredients in this gel. For instance, concurrent use of other topical corticosteroids may increase the risk of systemic corticosteroid effects, such as skin thinning or adrenal suppression, especially if used over large surface areas or for prolonged periods.

Additionally, patients who are on systemic antiviral medications should inform their healthcare provider, as the combined antiviral effect of systemic and topical acyclovir could potentially lead to increased side effects or altered therapeutic outcomes. Although systemic absorption of acyclovir from topical application is minimal, it is still prudent to consider the cumulative antiviral exposure, particularly in patients with renal impairment, where drug clearance may be affected.

For prescribers, it is crucial to evaluate the patient's overall medication regimen, including over-the-counter products and supplements, to identify any potential interactions. Special attention should be given to patients with a history of hypersensitivity to acyclovir, hydrocortisone, or any other components of the formulation, as this could lead to allergic reactions. Furthermore, prescribers should monitor for signs of local irritation or hypersensitivity reactions at the application site, which may necessitate discontinuation of the gel.

Patients should be advised to apply the gel as directed, avoiding contact with the eyes, mouth, and other mucous membranes. They should also be informed about the importance of adhering to the prescribed treatment duration and not to use the gel on broken or infected skin unless directed by a healthcare provider. If any unusual symptoms or side effects occur, patients should seek medical advice promptly.

If you have any questions or concerns regarding the use of Acyclovir 5%/Hydrocortisone Acetate 1% Topical Gel, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to ensure safe and appropriate use of this formulation.

How Does it Work

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The Acyclovir 5%/Hydrocortisone Acetate 1% Topical Gel is a specialized formulation designed to deliver targeted treatment for viral skin infections, such as herpes simplex, while simultaneously addressing inflammation and discomfort associated with these conditions. This semisolid gel is dispensed through a convenient pump mechanism, ensuring precise and controlled application directly to the affected area, which enhances the efficacy of the active ingredients.

Acyclovir, an antiviral agent, is the primary active ingredient in this formulation. It works by inhibiting the replication of viral DNA, thereby reducing the spread and severity of the viral infection. By targeting the virus at the site of infection, Acyclovir helps to reduce the duration and severity of outbreaks, promoting faster healing and minimizing the risk of transmission.

Hydrocortisone Acetate, a corticosteroid, is included in the formulation to address the inflammatory response often associated with viral infections. It works by reducing inflammation, redness, and swelling, providing symptomatic relief from itching and discomfort. The anti-inflammatory properties of Hydrocortisone Acetate complement the antiviral action of Acyclovir, offering a comprehensive approach to managing the symptoms and progression of viral skin infections.

The gel-like consistency of this formulation allows for easy application and rapid absorption into the skin, ensuring that the active ingredients are delivered efficiently to the site of infection. The pump mechanism not only facilitates precise dosing but also maintains the integrity and stability of the formulation by minimizing exposure to air and contaminants.

For prescribers, the combination of Acyclovir and Hydrocortisone Acetate in a topical gel provides a dual-action treatment option that can be tailored to the specific needs of the patient, enhancing therapeutic outcomes.

If you have any questions about this formulation or its use, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to ensure optimal treatment outcomes.

Frequently Asked Questions

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What is Acyclovir 5%/Hydrocortisone Acetate 1% Topical Gel used for?

This topical gel is used for the treatment of skin conditions caused by viral infections, such as cold sores, and to reduce inflammation and itching associated with these conditions.

How should I apply the Acyclovir 5%/Hydrocortisone Acetate 1% Topical Gel?

Dispense the gel through the pump mechanism and apply a thin layer to the affected area of the skin. Ensure the area is clean and dry before application for optimal absorption.

How often should I use this topical gel?

Follow your healthcare provider's instructions, but typically, it is applied 2 to 5 times daily, depending on the severity of the condition being treated.

Can I use this gel on open wounds or broken skin?

No, you should not apply this gel to open wounds or broken skin. It is intended for use on intact skin only.

Are there any side effects associated with this topical gel?

Some users may experience mild skin irritation, redness, or itching at the application site. If these symptoms persist or worsen, consult your healthcare provider.

Can I use this gel if I am pregnant or breastfeeding?

Consult your healthcare provider before using this gel if you are pregnant or breastfeeding to ensure it is safe for you and your baby.

How should I store the Acyclovir 5%/Hydrocortisone Acetate 1% Topical Gel?

Store the gel at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

Can I use other skin products while using this gel?

Consult your healthcare provider before using other skin products in conjunction with this gel to avoid potential interactions or reduced effectiveness.

What should I do if I experience an allergic reaction to this gel?

If you experience symptoms of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, discontinue use immediately and seek medical attention.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Acyclovir 5%/Hydrocortisone Acetate 1% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Twice daily