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Amantadine HCl 100 mg/ml Oral Liquid (Gluten Free)

Amantadine HCl 100 mg/ml Oral Liquid (Gluten Free) is a specially formulated medication designed for oral administration. This liquid formulation provides a convenient and easily ingested dosage form, ensuring accurate delivery of medication. It is particularly beneficial for individuals who find swallowing solid dosage forms challenging, such as pediatric and geriatric populations.

This formulation contains Amantadine HCl, a medication primarily used to treat and prevent certain strains of influenza A. It is also used to treat Parkinson's disease and "Parkinson-like" symptoms such as stiffness and shaking that may be caused by the use of certain drugs. Being gluten-free, it is suitable for individuals with gluten intolerance or celiac disease.

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Formula Information

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This formulation, Amantadine HCl 100 mg/ml Oral Liquid (Gluten Free), is a specially designed liquid medication intended for oral administration. It provides a convenient and easily ingested dosage form for accurate delivery of medication. This formulation is often used when swallowing solid dosage forms is challenging, such as in pediatric and geriatric populations, or for individuals with dysphagia.

Amantadine HCl is an antiviral medication that is primarily used to prevent or treat certain influenza infections. It works by blocking the actions of viruses in your body. In addition to its antiviral properties, Amantadine HCl is also used to treat Parkinson's disease and "Parkinson-like" symptoms such as stiffness and shaking that may be caused by the use of certain drugs. It works by restoring the balance of natural substances (neurotransmitters) in the brain.

Being in a liquid form, this formulation allows for precise dosing adjustments, which is particularly beneficial for patients who require individualized dosing regimens. The gluten-free aspect of this formulation makes it suitable for patients with celiac disease or gluten sensitivity, ensuring that they can take this medication without any adverse reactions related to gluten.

It is important to note that this medication should be used under the supervision of a healthcare provider, and it is crucial to follow the prescribed dosage to ensure its effectiveness and to minimize potential side effects. Side effects may include dizziness, lightheadedness, or trouble sleeping. If these effects persist or worsen, patients should promptly inform their doctor or pharmacist.

For prescribers, it is essential to consider the patient's overall health status, other medications being taken, and the patient's specific disease state when prescribing this formulation. Regular monitoring and follow-up are necessary to assess the patient's response to the medication and to make any necessary dosage adjustments.

If you have any questions about this formulation or its use, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always ready to assist you.

Drug Interactions

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Amantadine HCl is an antiviral medication that is also used in the treatment of Parkinson's disease and certain movement disorders caused by certain psychiatric drugs. It works by blocking the actions of viruses in your body, and it also affects certain chemicals in the nervous system that may help improve movement disorders.

Amantadine HCl may interact with several other medications, which can affect how it works or increase the risk of serious side effects. It is important to keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.

Some products that may interact with Amantadine HCl include anticholinergic drugs (such as scopolamine, certain antihistamines like diphenhydramine), certain drugs used for bladder control (such as oxybutynin, tolterodine), other drugs that can cause drowsiness (including alcohol, marijuana, drugs for sleep or anxiety such as alprazolam, zolpidem, muscle relaxants, and narcotic pain relievers such as codeine).

Amantadine HCl can also interact with certain medications for mental/mood conditions (such as antipsychotics, antidepressants), certain medications for high blood pressure (such as beta blockers like metoprolol, calcium channel blockers like diltiazem), and certain medications for stomach/intestinal diseases (such as drugs for acid reflux, ulcers).

Do not start, stop, or change the dosage of any medicines without your doctor's approval. If you are taking other drugs that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana, drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine), the risk of drowsiness may be increased.

It is also important to note that Amantadine HCl can cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using Amantadine HCl, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using Amantadine HCl safely.

This document does not contain all possible drug interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

If you have any questions about the potential interactions of Amantadine HCl, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

How Does it Work

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Amantadine HCl 100 mg/ml Oral Liquid (Gluten Free) is a specially formulated medication that works by influencing the actions of certain chemicals in the body, particularly a substance called dopamine. Dopamine is a neurotransmitter, a chemical that nerves use to communicate with one another. Amantadine has antiviral and antiparkinsonian properties, meaning it can be used to treat both viral infections and symptoms of Parkinson's disease.

When used as an antiviral, Amantadine inhibits the replication of certain viruses, specifically the Influenza A virus. It does this by blocking the action of a viral protein, preventing the virus from releasing its genetic material into the host cell. This stops the virus from multiplying and spreading, helping to control the infection.

As an antiparkinsonian agent, Amantadine works by increasing the amount of dopamine in the brain. Parkinson's disease is associated with low levels of dopamine, and by increasing these levels, Amantadine can help reduce the symptoms of the disease, such as stiffness, shaking, and difficulty with movement.

The oral liquid formulation of Amantadine HCl is particularly beneficial for patients who have difficulty swallowing solid dosage forms, such as tablets or capsules. This can include children, the elderly, or individuals with certain medical conditions. The liquid formulation allows for accurate dosing and is easy to ingest, making it a convenient option for these patients.

It's important to note that while Amantadine can help manage symptoms of Parkinson's disease and control Influenza A virus infections, it is not a cure for either condition. It should be used as part of a comprehensive treatment plan, under the supervision of a healthcare provider.

If you have any questions about Amantadine HCl 100 mg/ml Oral Liquid (Gluten Free), or if you would like more information about how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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Amantadine HCl is a medication known primarily for its antiviral and antiparkinsonian effects. However, it also has other potential applications that could benefit certain patient populations. Amantadine HCl in this specific liquid formulation may be particularly well-suited to off-label uses where other medication forms can be challenging due to dysphagia or palatability issues.

Aside from its primary uses, amantadine can be considered as a treatment option for fatigue in patients with multiple sclerosis (MS). It has been found to have a significant positive effect on both fatigue severity and impact on daily life. This medication may prove beneficial to the quality of life for MS patients struggling with chronic exhaustion. It's also used in certain rare neurological movement disorders such as Chorea caused by Huntington's disease or side effects of certain medications.

It's also worth noting that amantadine has been utilized in the treatment of Traumatic Brain Injury (TBI). Research shows it can promote arousal and cognitive recovery during the early weeks and months of recovery from TBI. Amantadine appears to expedite motor and cognitive recovery and may be particularly effective in patients with more severe injuries.

So whether it's managing viral diseases, Parkinson's disease, MS-related fatigue, certain movement disorders, or aiding recovery from TBI, Amantadine HCl can offer an important clinical solution. It's important to remember that the benefits should always be weighed against potential side effects, including but not limited to gastrointestinal disturbances, orthostatic hypotension, and neuropsychiatric conditions. The utility of this medication should be tailored to the individual patient's needs and continuously reassessed to ensure it continues to provide therapeutic benefit.

Physicians prescribing amantadine off-label should be mindful of its extensive renal elimination and adjust doses accordingly in those with renal impairment. Closer monitoring may be needed for the elderly patients or those with preexisting cardiac disease due to risk of QTc prolongation. Therefore, while beneficial, consultation with an experienced compounding pharmacist is always beneficial to optimize therapeutic effectiveness and minimize risks.

If you have any further questions about the potential use of Amantadine HCl 100 mg/ml Oral Liquid, or any other medication-related inquiries, don’t hesitate to reach out to our team at Bayview Pharmacy. Our goal is to assist you in getting the most benefit from your medications.

Frequently Asked Questions

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What is Amantadine HCl 100 mg/ml Oral Liquid (Gluten Free)?

Amantadine HCl 100 mg/ml Oral Liquid (Gluten Free) is a specially formulated liquid medication that is intended for oral administration. It provides a convenient and easily ingested dosage form for accurate delivery of medication, often used when swallowing solid dosage forms is challenging or for pediatric and geriatric populations.

Who is this formulation recommended for?

This formulation is primarily recommended for individuals that have difficulty swallowing solid dosage forms, which includes mainly pediatric and geriatric populations.

Is this formulation gluten free?

Yes, this formulation is gluten free which makes it safe for individuals who have gluten intolerance or celiac disease.

What is the active ingredient in this medication?

The active ingredient in this medication is Amantadine HCl, which is provided at a concentration of 100 mg/ml.

How is this medication consumed?

This medication is intended for oral administration, which means it should be swallowed, not injected or applied topically.

Can this medication be taken on an empty stomach?

Directions for use, such as whether it should be taken with food, will be given by the healthcare provider. If unsure, consult with your healthcare provider or pharmacist.

What is the storage requirement for this medication?

The specific storage instructions for this medication can be located on the medication label or accompanying paperwork, or consult your healthcare provider or pharmacist for storage information.

Are there any known side effects of this medication?

All medications may have side effects. For detailed information about potential side effects, please refer to the official patient information leaflet, contact your healthcare provider or pharmacist.

Is there a solid dosage form available for Amantadine HCl?

Yes, Amantadine HCl is available in other forms. However, the liquid form is an alternative designed to provide an easily ingested dosage form, especially for those who find swallowing solid dosage forms challenging.

How long does it take for this medication to work?

The onset of action for this medication could vary depending on various individual factors. Please consult your healthcare provider or pharmacist for accurate information.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
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