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Amlodipine 5 mg/5mL/Benazepril HCl 10 mg/5mL Oral Liquid

This formulation is a specially prepared oral liquid medication containing Amlodipine 5 mg and Benazepril HCl 10 mg per 5 mL. It is designed to provide an accurate dosage of medication in a form that is easy to ingest, making it particularly suitable for individuals who find swallowing solid dosage forms difficult, as well as for pediatric and geriatric populations. This medication is used to treat various disease states, including hypertension (high blood pressure) and coronary artery disease, which are conditions often associated with the need for long-term medication management. The combination of Amlodipine, a calcium channel blocker, and Benazepril, an ACE inhibitor, works synergistically to relax blood vessels and decrease blood pressure, thereby improving overall cardiovascular health.

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Oral Liquid
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Formula Information

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This formulation combines Amlodipine, a calcium channel blocker, and Benazepril HCl, an angiotensin-converting enzyme (ACE) inhibitor, in a liquid form for oral administration. The dosage is 5 mg of Amlodipine and 10 mg of Benazepril HCl per 5 mL of the liquid. This formulation is specifically designed to provide a convenient and easily ingested dosage form, often used when swallowing solid dosage forms is challenging or for pediatric and geriatric populations.

Amlodipine works by relaxing the blood vessels, allowing blood to flow more easily, thereby reducing the heart's workload. It is commonly used to treat high blood pressure (hypertension) and prevent chest pain (angina). On the other hand, Benazepril HCl works by blocking a substance in the body that causes blood vessels to tighten. As a result, blood vessels relax and widen, blood pressure is lowered, and the heart pumps blood more efficiently.

Together, Amlodipine and Benazepril HCl work synergistically to control high blood pressure, reducing the risk of strokes, heart attacks, and kidney problems. This combination medication is used when treatment with either Amlodipine or Benazepril alone has not been sufficient to control blood pressure. It is important to note that this medication does not cure high blood pressure but helps control it. Therefore, it must be taken regularly to be effective.

Patients should be aware that this medication may cause dizziness or lightheadedness. It is recommended to get up slowly when rising from a sitting or lying position. Alcohol and certain medications may interact with this formulation, so it is important to discuss all medications and supplements with your healthcare provider. As with all medications, this formulation should be taken exactly as prescribed by your healthcare provider.

Prescribers should monitor patients regularly to assess the effectiveness of the medication and adjust the dosage as necessary. It is important to consider the patient's overall health status, other medications, and response to therapy when prescribing this formulation.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

Drug Interactions

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Amlodipine and Benazepril HCl oral liquid is a combination medication used to treat high blood pressure (hypertension). Amlodipine is a calcium channel blocker that relaxes blood vessels and improves blood flow. Benazepril is an ACE inhibitor that helps to relax blood vessels, allowing blood to flow more smoothly and the heart to pump more efficiently.

While this medication is generally safe and effective, it may interact with other drugs. It's important to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements.

Drugs that may interact with this formulation include:

  • Potassium supplements or potassium-sparing diuretics: These can increase the level of potassium in your blood, which can be harmful when taking Benazepril.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): These can decrease the blood pressure lowering effects of this medication.
  • Other blood pressure medications: Taking these with Amlodipine/Benazepril can increase your risk of low blood pressure, kidney failure, and hyperkalemia (high levels of potassium in your blood).
  • Lithium: Benazepril can increase the amount of lithium in your body, leading to harmful side effects.

Alcohol may also interact with this medication, potentially increasing the blood pressure-lowering effects and causing dizziness or lightheadedness.

It's also important to note that this medication can interact with certain medical conditions. If you have a history of heart disease, liver disease, kidney disease, or diabetes, make sure to inform your healthcare provider as these conditions may affect how this medication works.

Remember, this is not a complete list of possible drug interactions. Always consult with your healthcare provider or pharmacist for more information. If you have any questions about this medication or its potential interactions, don't hesitate to reach out to us at Bayview Pharmacy. We're here to help.

How Does it Work

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Amlodipine/Benazepril HCl oral liquid is a combination medication that contains two active ingredients: Amlodipine, a calcium channel blocker, and Benazepril HCl, an angiotensin-converting enzyme (ACE) inhibitor. This specially formulated liquid medication is designed for oral administration and is particularly useful for patients who have difficulty swallowing solid dosage forms, such as tablets or capsules. It is also often used for pediatric and geriatric populations who may require a more easily ingested dosage form.

Amlodipine works by relaxing the muscles of your heart and blood vessels. It does this by blocking the action of calcium on the muscle cells in the heart and blood vessels. This makes it easier for the heart to pump blood and can reduce its workload. As a result, it helps to lower blood pressure and reduce the number of angina attacks.

Benazepril HCl, on the other hand, works by blocking a substance in the body that causes blood vessels to tighten. As a result, it relaxes the blood vessels, making it easier for your heart to pump blood around your body. This helps to lower blood pressure and also reduces the amount of work the heart has to do.

Together, Amlodipine and Benazepril HCl work synergistically to control high blood pressure (hypertension), reducing the risk of strokes, heart attacks, and kidney problems. It's important to note that this medication does not cure high blood pressure; it merely keeps it under control. Therefore, it's crucial to continue taking this medication even if you feel well.

As compounding pharmacists, we can customize this medication to meet the unique needs of each patient. This includes adjusting the concentration of the active ingredients, altering the flavor to make it more palatable, or even changing the form of the medication if necessary. We work closely with healthcare providers to ensure that each patient receives the most effective and appropriate treatment for their condition.

If you have any questions about Amlodipine/Benazepril HCl oral liquid or any other medication, please don't hesitate to reach out to us. We're here to help and provide you with the information you need to make informed decisions about your healthcare.

Other Uses

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Amlodipine/Benazepril HCl Oral Liquid is typically used in the management of hypertension and to prevent chest pain (angina). However, it may be used "off-label" for other purposes in accordance with healthcare provider's guidance. Amlodipine is a calcium channel blocker and can be used off-label for Raynaud's syndrome, a disease that affects the blood flow to the skin, leading to discomfort in hands and feet. Benazepril, an angiotensin-converting enzyme (ACE) inhibitor, can also be used in managing congestive heart failure or kidney disease associated with diabetes, besides hypertension.

Patients should understand that using this medication for other uses still maintains similar side effect profiles. Common side effects include headache, flushing, or tiredness. Serious side effects may include palpitations, edema, or symptoms associated with an allergic reaction. Regular follow-ups with the prescriber and routine blood pressure monitoring is strongly recommended.

Furthermore, prescribers should consider that this liquid formulation can be more beneficial in patients with dysphagia or having difficulty swallowing solid dosage forms, and can be conveniently used in pediatric and geriatric patients. When prescribing for off-label use, the risk-benefit ratio should be evaluated carefully, and patients should be closely monitored for any potential adverse effects.

Should you have any queries about this specific formulation or its use, we welcome you to reach out to us at Bayview Pharmacy. Our experienced team of compounding pharmacists is always ready to assist you with your medication formulating needs and concerns.

Frequently Asked Questions

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What is Amlodipine 5 mg/5mL/Benazepril HCl 10 mg/5mL Oral Liquid?

It is a compounded liquid medication of two active ingredients, Amlodipine and Benazepril HCl, intended for oral administration. It is designed to provide the accurate delivery of these medications in a form that is easy to ingest, often used for patients who find it difficult to swallow solid dosage forms.

Who is the intended user for Amlodipine/Benazepril HCl Oral Liquid?

The formulation is used when swallowing solid dosage forms is challenging, and hence can be taken by individuals who have difficulty swallowing solid pills, including pediatric and geriatric populations.

How should this medication be stored?

As with most medications, it should be stored at room temperature, away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Does the Amlodipine/Benazepril HCl Oral Liquid have any side effects?

All medications have potential side effects. Common side effects of this medication could include dizziness, lightheadedness, or dry cough. Patients should contact their healthcare provider if these side effects persist or worsen.

How should Amlodipine/Benazepril HCl Oral Liquid be taken?

This medication should be taken orally, usually once a day or as directed by your healthcare provider. The dosage is based on the patient's condition and response to treatment.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Can Amlodipine/Benazepril HCl Oral Liquid interact with other medications?

Yes, drug interactions can occur with this medication. It's important to tell your healthcare provider about all the medications you're currently taking, including over-the-counter drugs and dietary supplements, to avoid potential interactions.

Can I drink alcohol while taking Amlodipine/Benazepril HCl Oral Liquid?

It's best to consult with your healthcare provider about this, as drinking alcohol may further lower your blood pressure and increase side effects of the medication.

What if I accidently take an overdose of Amlodipine/Benazepril HCl Oral Liquid?

If someone has overdosed and has symptoms such as passing out or trouble breathing, call 911 immediately. Otherwise, call a poison control center right away. Symptoms of overdose may include severe dizziness, fainting, and unusually fast or slow heartbeat.

Is Amlodipine/Benazepril HCl Oral Liquid safe for pregnant or breastfeeding women?

This medication should not be used during pregnancy unless clearly needed. It may harm an unborn baby. It is unknown whether this medication passes into breast milk. Consult your healthcare provider before breastfeeding.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
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