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Amlodipine Besylate 0.87 mg/0.1 mL/Benazepril HCl 1.15 mg/ml Topical Gel

Bayview Pharmacy compounds Amlodipine Besylate/Benazepril HCl Topical Gel to support patients with hypertension, angina, heart failure, and more. Learn more today.
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Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Benazepril Hydrochloride
Amlodipine Besylate
Topical Gel
6530890502a0a5bbc17043ad

Formula Information

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Drug Interactions

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Amlodipine Besylate and Benazepril HCl are both medications used to treat high blood pressure. Amlodipine is a calcium channel blocker that relaxes blood vessels and improves blood flow. Benazepril is an ACE inhibitor that prevents the body from creating a hormone known to increase blood pressure. When combined in a topical gel, these medications can provide targeted treatment for localized areas of the body.

However, it's important to be aware of potential drug interactions. Amlodipine Besylate and Benazepril HCl can interact with a variety of other medications, potentially altering their effectiveness or increasing the risk of side effects.

For instance, using Amlodipine Besylate and Benazepril HCl with other medications that lower blood pressure, such as diuretics or beta-blockers, can result in excessively low blood pressure (hypotension). Symptoms of hypotension can include dizziness, fainting, and in severe cases, shock.

These medications can also interact with certain heart medications, such as digoxin or sotalol, potentially leading to an irregular heartbeat or other heart-related complications. If you're taking any heart medications, it's crucial to discuss this with your healthcare provider before starting treatment with Amlodipine Besylate and Benazepril HCl.

Additionally, Amlodipine Besylate and Benazepril HCl can interact with certain medications used to treat diabetes, such as insulin or oral hypoglycemics. This interaction can potentially lead to dangerously low blood sugar levels (hypoglycemia). Symptoms of hypoglycemia can include confusion, dizziness, and in severe cases, loss of consciousness.

Lastly, these medications can interact with certain nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen. This interaction can potentially lead to kidney problems, especially in older adults. If you're taking any NSAIDs, it's important to discuss this with your healthcare provider before starting treatment with Amlodipine Besylate and Benazepril HCl.

This is not a complete list of potential drug interactions. Always inform your healthcare provider of all medications, supplements, and herbal products you are currently taking to avoid any unexpected interactions. If you have any questions or concerns, don't hesitate to reach out to us at Bayview Pharmacy.

How Does it Work

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Amlodipine Besylate and Benazepril HCl Topical Gel is a unique formulation that combines two active ingredients, Amlodipine Besylate and Benazepril HCl, in a gel-like consistency for topical application. This formulation is designed to be dispensed through a pump mechanism, which allows for easy and precise application on the skin.

Amlodipine Besylate is a calcium channel blocker that works by relaxing the muscles of your heart and blood vessels. It is commonly used to treat high blood pressure (hypertension) and angina (chest pain). When applied topically, Amlodipine Besylate is absorbed through the skin and into the bloodstream, where it can exert its effects on the cardiovascular system.

Benazepril HCl, on the other hand, is an angiotensin-converting enzyme (ACE) inhibitor. It works by blocking a substance in the body that causes blood vessels to tighten. As a result, Benazepril HCl relaxes the blood vessels, making it easier for the heart to pump blood and reducing blood pressure. Like Amlodipine Besylate, Benazepril HCl is also absorbed through the skin when applied topically.

The combination of Amlodipine Besylate and Benazepril HCl in a topical gel formulation provides a targeted treatment for hypertension and angina. By applying the gel directly to the skin, the active ingredients can be absorbed directly into the bloodstream, bypassing the digestive system and reducing the risk of systemic side effects.

It's important to note that while this formulation can help manage symptoms of hypertension and angina, it is not a cure. Patients should continue to follow their healthcare provider's advice regarding lifestyle changes, such as diet and exercise, in addition to using this medication.

If you have any questions about the Amlodipine Besylate/Benazepril HCl Topical Gel, or if you would like more information about how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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Amlodipine Besylate and Benazepril HCl Topical Gel, a semi-solid formulation predominantly used for cardiovascular conditions due to its active ingredients, can also have some off-label uses. For instance, a novel off-label use can be in the management of Raynaud's syndrome. This rare disorder of the blood vessels generally affects the fingers and toes, causing them to feel numb and cold in response to cold temperatures or stress. In Raynaud's syndrome, amlodipine induces vasodilation which helps increase blood flow to the affected areas, potentially providing symptom relief.

In addition, this topical gel might be beneficial in conditions like hypertrophic scars and keloids. These conditions are characterized by the overgrowth of fibrous tissue following skin injuries, leading to raised scars. Given the indirect effect of amlodipine on collagen synthesis, it could potentially alleviate the clinical symptoms of hypertrophic scars and keloids though notably, this use is also not validated by enough complexity of research and clinical trials.

Further, it is of utmost importance that patients do not use this formulation for purposes other than it has been prescribed for. Self-medication can lead to dangerous health consequences. It is always advisable to consult with a healthcare provider if considering this medication for any other use not directly prescribed.

Healthcare providers interested in prescribing this formulation for any off-label use should undertake intensive discussions with their patients, clearly elucidating the potential benefits and risks, and monitor the patient closely for side effects or potential complications. It's critical to note that any off-label application should be based on sound medical judgment and high-level clinical evidence.

Please feel free to reach out to us at Bayview Pharmacy with any questions or for further information. We boast a team of compounding pharmacists with comprehensive knowledge in topical semi-solid formulations, and we are always here to assist you.

Frequently Asked Questions

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What is Amlodipine Besylate 0.87 mg/0.1 mL/Benazepril HCl 1.15 mg/ml Topical Gel?

This is a compounded treatment in gel form containing Amlodipine Besylate and Benazepril HCl. It's applied topically, with specific doses of the active ingredients delivered through a pump mechanism.

How do I use Amlodipine Besylate / Benazepril HCl Topical Gel?

This compounded topical gel should be used as directed by your healthcare provider. It is generally applied directly to the skin and absorbed for targeted treatment.

Why is this medication provided in a gel format?

The gel format allows for ease of application to the skin, targeting specific areas for treatment. This form also allows for consistent, precise dosage with the help of a pump mechanism.

Can I use other skin products alongside this topical gel?

Please consult with your healthcare provider before using other skin products with Amlodipine Besylate / Benazepril HCl Topical Gel.

How should I store Amlodipine Besylate / Benazepril HCl Topical Gel?

This medication should be stored at room temperature, away from direct light and heat. Keep it out of reach of children and pets.

What are the active ingredients in this formulation?

The active ingredients in this formulation are Amlodipine Besylate and Benazepril HCl.

What should I do if I forget to apply the gel?

If you forget to apply your dosage at the scheduled time, apply it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Can I stop using Amlodipine Besylate / Benazepril HCl Topical Gel whenever I feel my symptoms have improved?

No, it's important to complete the full course of treatment as directed by your healthcare provider. Stopping the medication prematurely may result in a return or worsening of symptoms.

If I experience any side effects, what should I do?

If you experience any adverse effects while using Amlodipine Besylate / Benazepril HCl Topical Gel, please contact your healthcare provider immediately for guidance.

Who should not use Amlodipine Besylate / Benazepril HCl Topical Gel?

Individuals with known hypersensitivity to Amlodipine, Benazepril, or any other components of the gel should not use this medication. Always discuss your medical history and current medications with your healthcare provider before starting any new treatment.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Related Formulas

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NY, NJ, NH, FL, and ME. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Amlodipine Besylate 0.87 mg/0.1 mL/Benazepril HCl 1.15 mg/ml Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)