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The Buprenorphine HCl 0.864 mg/ml Sublingual Liquid is a specially formulated medication designed for sublingual administration. This means it is intended to be administered under the tongue using the provided dropper bottle. This method allows for precise and controlled dosing, ensuring the correct amount of medication is delivered each time.
The sublingual administration route facilitates rapid absorption of the active ingredient, Buprenorphine HCl, into the bloodstream via the highly vascularized sublingual mucosa. This results in efficient and targeted delivery of the medication, providing fast-acting effects and bypassing the digestive system, which can sometimes hinder the effectiveness of certain medications.
This formulation is used to treat various disease states. Please consult with your healthcare provider to determine if this medication is suitable for your specific condition.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
This formulation of Buprenorphine HCl 0.864 mg/ml Sublingual Liquid is specifically designed for sublingual administration, meaning it is to be placed under the tongue. The medication is dispensed in a dropper bottle, which allows for precise and controlled dosing. This method of administration facilitates rapid absorption of the medication into the bloodstream through the highly vascularized sublingual mucosa. This provides efficient and targeted delivery for fast-acting effects and bypasses the digestive system, which can often degrade or slow the absorption of certain medications.
Buprenorphine HCl is a powerful opioid medication used to treat severe pain. It can also be used as part of a comprehensive treatment program for opioid use disorder (OUD), which includes counseling and psychosocial support. Buprenorphine works by binding to the same receptors in the brain that opioids do, helping to prevent withdrawal symptoms and reduce cravings. It is a partial agonist, meaning it does not produce the same level of euphoria or respiratory depression as full opioid agonists, making it a safer alternative for long-term management of OUD.
It should be used as part of a broader treatment approach that includes counseling and other behavioral therapies to provide patients with a more holistic approach to their recovery.
Patients should be aware that Buprenorphine HCl can cause side effects, including nausea, vomiting, constipation, and drowsiness. It can also cause more serious side effects such as respiratory distress if not used as directed. It is important to use this medication under the supervision of a healthcare provider and to follow all dosing instructions carefully.
Prescribers should be aware that Buprenorphine HCl is a Schedule III controlled substance, meaning it has potential for abuse, although less than Schedule I and II substances. It should be prescribed with caution, and patients should be closely monitored for signs of misuse, abuse, and addiction.
If you have any questions about this formulation of Buprenorphine HCl 0.864 mg/ml Sublingual Liquid, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.
Buprenorphine HCl is a potent opioid medication used primarily for the treatment of opioid addiction, chronic pain, and acute pain. It works by binding to the opioid receptors in the brain, thereby reducing the symptoms of opioid withdrawal and cravings. However, like all medications, Buprenorphine HCl can interact with other drugs, potentially altering its effectiveness or increasing the risk of adverse effects.
One of the most significant interactions is with other central nervous system (CNS) depressants, such as benzodiazepines, alcohol, and other opioids. Concurrent use of these substances can lead to profound sedation, respiratory depression, coma, and even death. Therefore, it is crucial to avoid the use of other CNS depressants while taking Buprenorphine HCl unless under the direct supervision of a healthcare provider.
Another important interaction is with medications that inhibit or induce the cytochrome P450 3A4 enzyme system, which metabolizes Buprenorphine HCl in the liver. Drugs that inhibit this enzyme, such as ketoconazole, erythromycin, and grapefruit juice, can increase the levels of Buprenorphine HCl in the body, potentially leading to an overdose. On the other hand, drugs that induce this enzyme, such as rifampin, phenytoin, and St. John's wort, can decrease the levels of Buprenorphine HCl, potentially leading to a lack of efficacy.
Furthermore, Buprenorphine HCl can interact with antiretroviral drugs used to treat HIV, such as atazanavir and ritonavir. These drugs can increase the levels of Buprenorphine HCl in the body, potentially leading to an overdose. Therefore, dose adjustments may be necessary when these drugs are used concurrently.
Lastly, Buprenorphine HCl can interact with serotonergic drugs, such as selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), and monoamine oxidase inhibitors (MAOIs). Concurrent use of these drugs can lead to serotonin syndrome, a potentially life-threatening condition characterized by agitation, hallucinations, rapid heartbeat, fever, and other symptoms.
It is important to note that this is not an exhaustive list of all potential drug interactions. Patients should always inform their healthcare provider of all medications, supplements, and herbal products they are currently taking. Additionally, they should never start or stop any medication without first consulting their healthcare provider.
If you have any questions about Buprenorphine HCl or its potential drug interactions, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.
Buprenorphine HCl 0.864 mg/ml Sublingual Liquid works by binding to the opioid receptors in the brain. These receptors are responsible for the feelings of pain and pleasure. Buprenorphine is a partial opioid agonist, which means it partially activates these receptors to help reduce the sensation of pain. At the same time, it also blocks other opioids from binding to these receptors, which can help prevent the effects of opioid withdrawal.
When administered sublingually, the medication is rapidly absorbed into the bloodstream through the highly vascularized sublingual mucosa. This method of administration bypasses the digestive system, which can often delay the onset of the medication's effects and potentially degrade the medication. By bypassing the digestive system, the medication can provide faster relief from pain and withdrawal symptoms.
This formulation is specifically designed for administration under the tongue, dispensed in a dropper bottle. This allows for precise and controlled dosing, which is particularly important for medications like Buprenorphine that can have significant side effects if taken in excess. The dropper bottle also makes it easier for patients to self-administer the medication, which can be particularly beneficial for those who are managing chronic pain or opioid dependence at home.
Buprenorphine HCl 0.864 mg/ml Sublingual Liquid is used to treat moderate to severe chronic pain when other pain treatments do not work or cannot be tolerated. It is also used as part of a comprehensive treatment program for opioid dependence, which may include counseling and psychosocial support. It can help to reduce withdrawal symptoms and cravings, making it easier for patients to stop using opioids.
It's important to note that while Buprenorphine can help manage pain and withdrawal symptoms, it is not a cure for opioid dependence. Long-term recovery from opioid dependence often requires ongoing treatment and support. It's also important to use Buprenorphine as directed by a healthcare provider, as misuse can lead to addiction, overdose, or death.
If you have any questions about Buprenorphine HCl 0.864 mg/ml Sublingual Liquid, or if you need help understanding how to use this medication, please reach out to us. We are here to help.
This is a liquid formulation of the medication Buprenorphine HCl, specifically designed for administration under the tongue. This formulation is dispensed in a dropper bottle and allows for precise and controlled dosing.
It is administered sublingually, meaning it is placed directly under the tongue. This method allows for the active ingredient to be rapidly absorbed into the bloodstream through the highly vascularized sublingual mucosa.
The sublingual method provides efficient and targeted delivery for fast-acting effects and can bypass the digestive system. This is beneficial because it can mean fewer side effects and the active ingredient can begin working more quickly.
The dropper bottle allows for precise and controlled dosing, ensuring the patient receives the correct amount of medication.
No, this formulation is not designed to be swallowed. It is meant to be administered under the tongue in order to facilitate rapid absorption into the bloodstream.
Yes, due to its method of administration and the nature of the sublingual mucosa, this formulation can begin working more quickly than medications that need to be digested first.
While it may be safe to take with other medicines, you should always inform your healthcare provider about all the medications you're currently taking. This will help avoid any potential interactions or side effects.
This medication should only be used by the individual it has been prescribed for. Always follow the instructions provided by your healthcare provider, and do not share your medication with others.
If you miss a dose, take it as soon as you remember. If it's close to the time of your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time to compensate for the missed dose.
If you suspect an overdose, seek emergency medical attention or call the Poison Help line. Overdose symptoms may include severe drowsiness, cold and clammy skin, slow heart rate, shallow breathing, fainting, or coma.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Place dropper amount under the tongue
