Check out our most popular compounded medications! Get Started
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Prepared to a prescriber's order for one patient. Not FDA-approved.
Chlorhexidine gluconate is a broad-spectrum antiseptic that compounding pharmacies prepare as oral rinses, topical solutions and gels by prescription.
Chlorhexidine is a bisbiguanide antiseptic. The molecule carries a positive charge, so it binds to the negatively charged surfaces of bacterial cell walls and damages the cell membrane; at low concentrations it halts bacterial growth and at higher concentrations it kills bacteria and fungi. It also sticks to teeth, gums and saliva proteins, so activity in the mouth persists for hours after a rinse. Manufactured products include the prescription 0.12% oral rinse (Peridex, Periogard and generics), FDA-approved as part of a professional program for gingivitis, and over-the-counter skin antiseptics such as Hibiclens and ChloraPrep for skin cleansing and preoperative preparation. A prescriber might order compounded chlorhexidine for a vehicle without alcohol, dye or a particular flavor, a strength or form not manufactured, or a combination with another ingredient. Compounded preparations are not FDA-approved and require a prescription.
Do not use chlorhexidine if you have ever reacted to it. FDA has warned that chlorhexidine can cause rare but serious allergic reactions, including anaphylaxis, within minutes of skin or mouth exposure; stop using it and get emergency care for trouble breathing, hives, facial swelling, dizziness or a rapid heartbeat. Oral rinses commonly stain teeth, tongue and fillings, increase tartar and change taste, and rare permanent taste change has been reported; regular dental cleanings help. Keep skin products out of the eyes, ears, mouth and deep wounds; they can burn the skin of premature infants and children under two. Chlorhexidine is barely absorbed, and the rinse label lists no drug interactions. The rinse label says to use it in pregnancy only if clearly needed; LactMed states oral rinse use by a nursing mother is unlikely to affect her infant. If side effects bother you, talk to your prescriber or pharmacist.
Chlorhexidine gluconate is a cationic bisbiguanide. It binds phosphate and sulfate groups on bacterial envelopes, disrupts the cytoplasmic membrane with leakage of potassium and small molecules, and at sustained higher concentrations precipitates cytoplasmic contents, giving bactericidal and fungicidal action and inactivation of several enveloped viruses; gram-positive organisms are generally more susceptible. Substantivity to oral mucosa and tooth surfaces supports activity for up to 12 hours. About 30% of a rinse dose is retained in the oral cavity and released slowly; GI absorption is poor, with roughly 90% of an ingested dose recovered in feces and under 1% in urine. Labeled indication: the 0.12% oral rinse (Peridex, Periogard, generics) for gingivitis between dental visits as part of a professional program; it is not established for periodontitis. OTC chlorhexidine skin antiseptics (Hibiclens, ChloraPrep and store brands) are labeled for skin cleansing and preoperative preparation. The dental literature also describes chlorhexidine gels, chips and varnishes. Strength, vehicle and duration are per prescriber. Monitoring is clinical: dental prophylaxis at intervals no longer than six months during rinse use, staining and calculus, taste change, mucosal desquamation, and hypersensitivity history before exposure. Low-level exposure has been linked to cross-resistance in some bacteria. Not a controlled substance.
Wash your hands. Fill the applicator to the mark on your label, or use a prefilled applicator. Lie on your back with knees bent, insert the applicator gently as far as is comfortable, and push the plunger slowly until it stops. Remove the applicator; wash a reusable one with mild soap and water or discard a single-use one. Bedtime use is common. Wash your hands afterward.
A gel can have a nonaqueous or a water-based base, and USP <795> sets its default beyond-use date by water content, not by the word gel. A nonaqueous gel usually carries a beyond-use date of up to 180 days at room temperature or refrigerated. A water-based gel carries up to 35 days with a preservative, or 14 days refrigerated without one. Your label states which applies. Keep the container closed, keep from freezing, keep out of reach of children, and discard after the beyond-use date on your label.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Insert/apply intravaginally
