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Clobetasol Propionate 0.05%/Zinc Sulfate 2.5% Topical Cream

FDA-approved generic
Dose form
Topical Cream
Active ingredients
Clobetasol Propionate
Zinc Sulfate

This formulation is a combination of Clobetasol Propionate 0.05% and Zinc Sulfate 2.5% in a topical cream format. It is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. The cream is intended for localized treatment, facilitating the absorption of the active ingredients directly at the site of application.

Clobetasol Propionate is a potent corticosteroid that helps to reduce inflammation and immune responses. It is commonly used to treat various skin conditions such as eczema, psoriasis, and dermatitis. Zinc Sulfate, on the other hand, is known for its astringent and antiseptic properties. It helps in healing the skin and reducing irritation.

Together, these two active ingredients work synergistically to alleviate symptoms associated with the aforementioned disease states, providing relief from inflammation, itching, and redness. The pump mechanism allows for a controlled and convenient application, ensuring that the right amount of medication is applied to the affected area.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Clobetasol Propionate
Zinc Sulfate
Topical Cream
653f8b4d7c5eebceb73c5bcc

Formula Information

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This formulation combines Clobetasol Propionate 0.05% and Zinc Sulfate 2.5% in a topical cream, dispensed via a pump mechanism for easy and controlled application. Clobetasol Propionate is a potent corticosteroid that works by reducing inflammation, itching, and redness. It is commonly used to treat a variety of skin conditions such as eczema, psoriasis, and dermatitis. Zinc Sulfate, on the other hand, is known for its astringent and antiseptic properties. It helps in healing the skin and reducing the severity of acne and other skin lesions.

The combination of these two active ingredients in a single formulation provides a comprehensive approach to managing various skin conditions. The anti-inflammatory action of Clobetasol Propionate effectively reduces the symptoms of skin inflammation, while the healing properties of Zinc Sulfate promote skin recovery.

The cream is designed for localized treatment, meaning it should be applied directly to the affected area of the skin. The pump mechanism allows for a controlled application, ensuring that the right amount of cream is dispensed each time. This helps to minimize the risk of overuse or misuse, which can lead to side effects such as skin thinning or hormonal imbalances. It is important to use this medication as directed by your healthcare provider, and not to apply more than the recommended dose.

As with any medication, it is important to discuss any potential side effects or interactions with your healthcare provider. Some people may experience side effects such as burning, stinging, or itching at the application site. If these symptoms persist or worsen, contact your healthcare provider immediately. Also, inform your healthcare provider of any other medications you are currently taking, as certain drugs may interact with this formulation.

If you have any questions or concerns about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to assist you. We are committed to providing you with the highest quality of care and ensuring that you have all the information you need to make informed decisions about your health.

Drug Interactions

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Clobetasol Propionate 0.05%/Zinc Sulfate 2.5% Topical Cream is a potent corticosteroid combined with an astringent and antiseptic agent. It is used to treat a variety of skin conditions such as eczema, psoriasis, dermatitis, and allergies. The clobetasol propionate works by reducing the swelling, itching, and redness that can occur in these types of conditions, while the zinc sulfate helps to promote healing of the skin.

It's important to be aware of potential drug interactions when using this formulation. While topical application generally reduces the risk of systemic interactions, certain medications and substances can still interact with the active ingredients. For instance, other corticosteroids or immunosuppressant drugs may increase the risk of side effects. Additionally, using other topical medications on the same area of skin can potentially cause increased absorption of both products, leading to an increased risk of systemic side effects.

Patients should avoid using other topical products on the same area where this cream is applied unless directed by a healthcare provider. This includes other prescription medications, over-the-counter products, and even certain cosmetics. If you are using other topical medications, it is important to allow a suitable time interval between applying different products.

It's also important to note that certain medical conditions can affect the use of this medication. For example, patients with a history of poor blood circulation, immune system problems, or certain skin conditions (such as rosacea, perioral dermatitis) should use this medication with caution. Always inform your healthcare provider of your complete medical history before starting any new medication.

While this formulation is generally well-tolerated, side effects can occur. These may include burning, stinging, itching, dryness, or redness at the application site. More serious side effects, such as skin thinning/discoloration, stretch marks, and hair bumps (folliculitis) may occur, especially with prolonged use. If you notice any of these effects, contact your healthcare provider promptly.

Remember, this medication is to be used only on the skin. Avoid getting this medication in your eyes, nose, or mouth. If you accidentally get this medication in these areas, rinse with plenty of water.

If you have any questions about this medication, its use, potential interactions, or your specific situation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help ensure you get the most benefit from your medications.

How Does it Work

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The Clobetasol Propionate 0.05%/Zinc Sulfate 2.5% Topical Cream is a potent formulation designed to treat a variety of skin conditions. The cream is a semisolid preparation dispensed in a pump mechanism, which allows for convenient and controlled application on the skin. This ensures that the active ingredients are localized to the area of treatment, maximizing their effectiveness while minimizing systemic absorption and potential side effects.

Clobetasol Propionate is a highly potent corticosteroid that works by reducing inflammation, itching, and redness. It does this by suppressing the immune response, which reduces the release of chemicals in the body that cause inflammation.

Zinc Sulfate, on the other hand, is an astringent and antiseptic. It works by forming a protective layer over the skin, which helps to soothe and heal the skin. It also has mild antibacterial properties, which can help to prevent infection in damaged skin. This makes it useful in treating conditions such as acne, minor skin irritations, and diaper rash.

Together, these two active ingredients work synergistically to provide relief from a variety of skin conditions. The Clobetasol Propionate reduces inflammation and itching, while the Zinc Sulfate helps to protect and heal the skin.

As with any medication, it's important to use this cream as directed by your healthcare provider. Overuse or misuse can lead to side effects, including skin thinning, stretch marks, and skin discoloration. If you have any questions about this formulation or how to use it, don't hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always here to help.

Other Uses

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Clobetasol Propionate 0.05%/Zinc Sulfate 2.5% Topical Cream in this dose form is typically prescribed to control inflammation and itching associated with various skin conditions such as psoriasis, eczema or dermatitis. Clobetasol propionate is a potent corticosteroid that works by reducing inflammation and suppresses immune responses, while Zinc sulfate helps to soothe the skin and promote the healing process.

Apart from these commonly recognized uses, this formulation may also be used in other off-label ways, mainly under the recommendation of a healthcare provider. For instance, this cream might be prescribed by a dermatologist for addressing lichen sclerosus, a condition that causes thinning and whitening of skin. Also, cases of discoid lupus erythematosus (DLE), a chronic skin condition characterized by inflammation and scarring type skin lesions which occur on the face, ears, scalp and at times on other body areas, might benefit from its use. The potent anti-inflammatory action of the cream could help control the symptoms and prevent scarring related to this condition.

Adverse effects may include skin thinning, stretch marks, and vein visibility. It is not recommended for extensive or long-term use.

In general, making use of this topical cream for disease states not originally intended may carry certain risks. As with any prescribed medication, it is crucial that the patient fully disclose their medical history, along with any other medications or supplements they are currently taking. This allows the healthcare provider to accurately assess potential risks and adjust the treatment plan accordingly.

If you have any questions or concerns about utilizing Clobetasol Propionate 0.05%/Zinc Sulfate 2.5% Topical Cream in a manner not stated above, or for a different condition than originally prescribed, please reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is here to help you understand all potential applications and precautions of your medications.

Frequently Asked Questions

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What is Clobetasol Propionate 0.05%/Zinc Sulfate 2.5% Topical Cream?

This is a compounded formulation cream that contains two active ingredients: Clobetasol Propionate and Zinc Sulfate. It is used to treat various skin conditions by reducing inflammation and irritation. The cream is a semisolid preparation that is dispensed in a pump mechanism for convenient and controlled application.

How should I use Clobetasol Propionate 0.05%/Zinc Sulfate 2.5% Topical Cream?

Apply the cream onto the affected area as directed by your healthcare provider. It is usually applied in a thin layer to the affected skin areas twice daily or as directed by your doctor. Remember to wash your hands thoroughly after application unless your hands are the area being treated.

What should I do if I miss a dose?

If you miss a dose, apply the cream as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Can I use this cream on my face?

Unless specifically instructed by your healthcare provider, avoid using this cream on your face, armpits, or groin area. If your doctor instructs you to use it on these delicate areas, it should be used sparingly and for a limited time.

What are the side effects of Clobetasol Propionate 0.05%/Zinc Sulfate 2.5% Topical Cream?

Side effects may include burning, stinging, itching, dryness, or redness at the application site. These effects should decrease with continual use. If these symptoms persist or worsen, immediately contact your healthcare provider.

Can I use Clobetasol Propionate 0.05%/Zinc Sulfate 2.5% Topical Cream if I am pregnant?

If you are pregnant, planning to become pregnant, or breastfeeding, you should consult your healthcare provider before using this cream. It should be used only when clearly needed and potential risks must be discussed.

Can I cover the treated area with a bandage after application?

Do not cover, bandage or wrap the area unless directed by your healthcare provider. This can increase absorption of the cream into your body and might lead to unwanted side effects.

What should I avoid while using this cream?

Avoid getting the cream in your eyes, nose or mouth. If this happens, rinse thoroughly with water. Also, avoid excessive sun exposure as this cream can make your skin more sensitive to sunlight.

How long should I use Clobetasol Propionate 0.05%/Zinc Sulfate 2.5% Topical Cream?

Do not use the cream for longer than the recommended period as it can cause side effects like skin thinning. Consult your healthcare provider for your personalised treatment plan.

Can I stop using the cream if my symptoms have improved?

Do not stop using the cream without consulting your healthcare provider, even if your symptoms have improved. A gradual reduction in dose may be recommended to prevent withdrawal symptoms.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Clobetasol Propionate 0.05%/Zinc Sulfate 2.5% Topical Cream
Topical Cream
30 g
controlled

Apply topically to affected area(s)