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Formulas

Clonidine 0.2% Topical Cream

FDA-approved generic
Dose form
Topical Cream
Active ingredients
Clonidine Hydrochloride

Clonidine 0.2% Topical Cream is a semisolid preparation, dispensed via a pump mechanism for easy and controlled application on the skin. This formulation is specifically designed for localized treatment, enabling direct absorption of the active ingredient, Clonidine, into the affected area.

This includes conditions such as neuropathic pain, complex regional pain syndrome, and other forms of chronic pain. The localized application allows for targeted relief, minimizing systemic side effects.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Clonidine Hydrochloride
Topical Cream
653faa0304e97f3d4eb13cfc

Formula Information

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Clonidine 0.2% Topical Cream is a specially formulated medication that is designed to be applied directly to the skin. This semisolid preparation is dispensed in a pump mechanism, which allows for convenient and controlled application. The active ingredient in this formulation is Clonidine, a medication that is primarily used to treat high blood pressure.

One of the key benefits of this formulation is that it allows for localized treatment. This means that the medication can be applied directly to the area of the body where it is needed most. This can be particularly beneficial for conditions such as neuropathic pain, where the pain is localized to a specific area. By applying the medication directly to the source of the pain, it can provide targeted relief without the systemic side effects that can occur with oral medications.

Clonidine works by stimulating alpha-2 adrenergic receptors, which results in decreased nerve signal transmission. This can help to reduce pain, inflammation, and other symptoms associated with various disease states. In addition to neuropathic pain, Clonidine 0.2% Topical Cream may also be used to treat conditions such as diabetic neuropathy, postherpetic neuralgia, and other types of chronic pain.

The medication should be applied as directed, and patients should not use more than the recommended dose. Side effects can include dry mouth, drowsiness, and low blood pressure, among others. If you experience any unusual or severe side effects, you should contact your healthcare provider immediately.

At Bayview Pharmacy, we are a team of knowledgeable compounding pharmacists who are here to help. We can provide detailed information about Clonidine 0.2% Topical Cream, including how to use it, what to expect, and how to manage any potential side effects. If you have any questions about this formulation, please don't hesitate to reach out to us. We are here to provide the support and guidance you need to manage your health effectively.

Drug Interactions

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Clonidine 0.2% Topical Cream is a medication that is primarily used to manage conditions such as hypertension, attention deficit hyperactivity disorder (ADHD), and certain types of pain. It works by stimulating alpha-2 adrenergic receptors in the brain, which decreases cardiac output and peripheral vascular resistance, leading to a decrease in blood pressure. It also has sedative effects which can help with ADHD and certain pain conditions.

However, it's important to be aware of potential drug interactions when using Clonidine 0.2% Topical Cream. This medication can interact with a number of other drugs, potentially altering their effects or increasing the risk of side effects. For instance, if Clonidine is taken with other medications that lower blood pressure, such as beta-blockers, calcium channel blockers, or diuretics, it can lead to an excessive drop in blood pressure, which can cause symptoms such as dizziness, lightheadedness, fainting, or even shock.

Clonidine can also interact with central nervous system depressants like alcohol, barbiturates, or benzodiazepines, leading to an increase in sedative effects. This can result in excessive drowsiness, confusion, and slow reflexes. Additionally, taking Clonidine with antidepressants or antipsychotics can alter the effects of these medications, potentially leading to an increase in side effects or a decrease in therapeutic effects.

Furthermore, Clonidine can interact with certain heart medications, such as digoxin, leading to an increase in the risk of side effects like slow heart rate or heart block. It can also interact with certain diabetes medications, potentially leading to an increase in blood sugar levels.

It's crucial for patients and prescribers to be aware of these potential interactions and to monitor for any signs of them. If you're a patient, make sure to inform your healthcare provider of all the medications you're currently taking, including over-the-counter drugs, herbal supplements, and vitamins. If you're a prescriber, make sure to review the patient's medication list thoroughly before prescribing Clonidine 0.2% Topical Cream.

If you have any questions about Clonidine 0.2% Topical Cream, its potential interactions, or its use in treating certain conditions, don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

How Does it Work

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Clonidine 0.2% Topical Cream is a specially formulated medication that is designed to be applied directly to the skin. The active ingredient in this formulation is Clonidine, a medication that is primarily used to treat high blood pressure. However, in this topical form, it can be used to treat a variety of other conditions, including certain types of pain and skin disorders.

The cream is a semisolid preparation that is dispensed using a pump mechanism. This design allows for convenient and controlled application of the medication, ensuring that the correct dose is applied each time. The cream is designed to be absorbed through the skin, allowing the active ingredient to work directly on the affected area. This localized treatment can provide targeted relief from symptoms, without the systemic effects that can occur with oral medications.

When applied to the skin, Clonidine works by stimulating certain receptors in the body known as alpha-2 adrenergic receptors. These receptors are found in various parts of the body, including the skin, and when activated, they can help to reduce inflammation and pain.

It's important to note that while Clonidine 0.2% Topical Cream can provide significant relief from symptoms, it is not a cure for the underlying condition. It should be used as part of a comprehensive treatment plan, under the supervision of a healthcare provider. As with any medication, it's important to use Clonidine 0.2% Topical Cream exactly as directed to ensure the best possible results.

If you have any questions about Clonidine 0.2% Topical Cream, or if you would like more information about how this medication works, please don't hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is always here to help.

Other Uses

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Clonidine 0.2% Topical Cream, despite its defined local application, has been found useful in managing a number of other health conditions. It has seen successful application as a non-opioid option for managing symptoms of opioid withdrawal. This is beneficial as it reduces the reliance on potentially addictive substances for treatment. Moreover, by applying it topically instead of ingesting orally, the drug is absorbed directly where needed, reducing the likelihood of systemic side effects.

An interesting use of Clonidine 0.2% Topical Cream is its ability to help with certain mental health conditions, for instance, tourette syndrome and attention deficit hyperactivity disorder (ADHD). Again, this method of drug delivery bypasses the systemic circulation, delivering the therapeutic effect right where it's needed, resulting in lesser side effects and stronger effectiveness.

Research has shown that Clonidine 0.2% Topical Cream can also improve asleep and hot flashes experienced by postmenopausal women. Similar cases have also been observed among patients undergoing cancer treatments or who pause hormonal medications. The cream, in such scenarios, helps manage these discomforting symptoms and improve the overall quality of life of these patients.

It's essential for patients and healthcare providers to know that although effective, this topical formulation requires care in application as well as monitoring for side effects, given its potent properties. Any potential interactions with other medications and overall health status must be evaluated before using this cream. Also, since it's a semisolid preparation, it can sometimes cause skin irritation or other reactions in some individuals. Therefore, starting with a small amount and waiting to see if there are any adverse reactions is recommended.

While we have attempted to cover the possible additional uses, we understand that each patient is unique and any medication usage should be approached on an individual basis. We highly recommend physicians and patients to communicate with us for any further information or personalized consultation on Clonidine 0.2% Topical Cream.

Frequently Asked Questions

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What is Clonidine 0.2% Topical Cream?

Clonidine 0.2% Topical Cream is a compounded formulation of Clonidine, a medication traditionally used to treat high blood pressure. When formulated into a cream at 0.2% concentration, it can be applied on the skin for localized treatment or absorption of the active ingredient.

How is Clonidine 0.2% Topical Cream supplied?

This medication is supplied in a semisolid form dispensed via a pump mechanism. The design ensures convenient and controlled application of the cream to the skin.

How does Clonidine 0.2% Topical Cream work?

The active ingredient in this cream, Clonidine, works by stimulating alpha-adrenoceptors in the brain, which results in reduced sympathetic tone (suppression of the body's 'fight or flight' response) and therefore reduced pain.

How do I apply Clonidine 0.2% Topical Cream?

Apply the cream directly to the affected area as instructed by your healthcare provider. Always ensure that your skin is clean and dry before application. Use the pump mechanism to dispense an appropriate amount of the cream, then gently rub the cream into the skin until it is fully absorbed.

Can there be side effects from using Clonidine 0.2% Topical Cream?

Yes, as with any medication, Clonidine 0.2% Topical Cream can cause side effects such as dry mouth, constipation, and drowsiness. If you experience any severe or troubling side effects, contact your healthcare provider immediately.

Who should avoid using Clonidine 0.2% Topical Cream?

People with an allergy to Clonidine or any component of the cream should avoid using it. Additionally, it is essential to discuss your medical history with your doctor before using the cream, especially if you have kidney disease, heart problems, or other serious health issues.

Can I cover the treated area after applying Clonidine 0.2% Topical Cream?

It's better not to cover the treated area unless specifically advised by your healthcare provider. Covering the area may increase the absorption of the medication, which can increase the risk of side effects.

Can I use Clonidine 0.2% Topical Cream if I am pregnant or breastfeeding?

It's best to consult your healthcare provider before using this medication if you're pregnant, planning to become pregnant, or breastfeeding. Although the risk to the fetus or nursing infant is considered low, it's essential to discuss any potential risks and benefits with your provider.

How should I store Clonidine 0.2% Topical Cream?

Store this medication at room temperature, away from heat and direct light. Do not freeze. Keep out of the reach of children.

What should I do if I miss a dose of Clonidine 0.2% Topical Cream?

If you miss a dose, apply it as soon as you remember. However, if it is near the time of the next dose, skip the missed dose, and resume your usual dosing schedule. Do not double the dose to catch up.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Clonidine 0.2% Topical Cream
Topical Cream
30 g
controlled

Apply topically to affected area(s)