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This formulation is a semisolid preparation of Collagenase 250 IU/g, Misoprostol 0.0024%, and Phenytoin 5% Topical Cream. It is dispensed in a pump mechanism for easy and controlled application on the skin.
Collagenase is an enzyme that breaks down collagen in damaged tissues, promoting wound healing. Misoprostol is a prostaglandin that helps to protect the stomach lining and reduce ulceration. Phenytoin is an anticonvulsant that also promotes healing by modulating the immune response and reducing inflammation.
This formulation is used to treat a variety of disease states. It can also be used to manage burns and other skin injuries. Additionally, it is used in the treatment of gastrointestinal ulcers, particularly those caused by nonsteroidal anti-inflammatory drugs (NSAIDs).
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
This formulation contains three active ingredients: Collagenase, Misoprostol, and Phenytoin. Each of these ingredients can interact with other medications, potentially altering their effects. It's important to inform your healthcare provider about all the medications you're currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements.
Collagenase, an enzyme that breaks down collagen in damaged tissues, can interact with anticoagulants like warfarin, increasing the risk of bleeding. If you're taking any blood-thinning medications, your healthcare provider may need to adjust your dosage or monitor you more closely while you're using this cream.
Misoprostol, a synthetic prostaglandin, is used in this formulation for its ability to promote healing and prevent ulcers. However, it can interact with antacids and other medications used to treat stomach acid disorders. These interactions can decrease the effectiveness of Misoprostol. Additionally, Misoprostol can increase the effects of certain drugs used to treat high blood pressure, such as beta-blockers, calcium channel blockers, and ACE inhibitors. This could potentially lead to excessively low blood pressure.
Phenytoin, an anticonvulsant, is included in this formulation for its ability to slow down impulses in the brain and aid in the healing of the skin. Phenytoin can interact with a wide range of medications, including other anticonvulsants, antidepressants, antifungal drugs, certain antibiotics, and some heart medications. These interactions can either increase or decrease the effectiveness of Phenytoin or the interacting drugs. In some cases, they can also increase the risk of side effects.
This formulation is designed to treat a variety of skin conditions. Collagenase helps to debride necrotic tissue and promote healing, Misoprostol aids in the prevention of ulcers and promotes healing, and Phenytoin also aids in the healing process and can help to reduce pain. However, due to the potential for drug interactions, it's important to use this medication under the supervision of a healthcare provider.
If you have any questions about this formulation or its potential interactions with other medications, please don't hesitate to reach out to us. We're here to help ensure that you can use this medication safely and effectively.
This unique formulation combines the therapeutic benefits of Collagenase, Misoprostol, and Phenytoin in a topical cream designed for localized treatment. The cream is dispensed in a pump mechanism, which allows for convenient and controlled application on the skin, ensuring that the active ingredients are absorbed effectively.
Collagenase, the first active ingredient, is an enzyme that breaks down collagen in damaged tissues within the skin. It is often used to promote wound healing, as it helps to remove dead skin and tissue, allowing for the growth of new, healthy tissue. In this formulation, Collagenase is present at a concentration of 250 IU/g, which is a potent dose capable of facilitating significant tissue repair.
Misoprostol, the second active ingredient, is a synthetic prostaglandin E1 analogue. It works by increasing the production of gastric mucus and bicarbonate, which helps to protect the stomach lining. In this topical formulation, Misoprostol is present at a concentration of 0.0024%. While Misoprostol is typically used to prevent stomach ulcers, in a topical formulation, it can help to protect the skin and promote healing.
The third active ingredient, Phenytoin, is an anticonvulsant that also has effects on the skin. At a concentration of 5%, Phenytoin can help to promote wound healing. It works by modulating the immune response, reducing inflammation, and promoting the growth of granulation tissue. This can help to speed up the healing process and reduce the risk of infection.
This formulation is particularly useful in treating a variety of disease states that affect the skin. The combined action of Collagenase, Misoprostol, and Phenytoin can help to promote wound healing, reduce inflammation, and protect the skin.
As compounding pharmacists, we are committed to providing the highest quality formulations to meet the unique needs of each patient. If you have any questions about this formulation, or if you would like to discuss how it could be used in your specific situation, please don't hesitate to reach out to us at Bayview Pharmacy. We are here to help.
This topical cream is designed for localized treatment or absorption of its active ingredients on the skin. Each ingredient has a different purpose. Collagenase helps to break down dead skin and tissues, Misoprostol assists with skin inflammation and wound healing, and Phenytoin contributes towards accelerating tissue healing.
The cream is dispensed in a pump mechanism which is designed for convenient and controlled application, allowing the user to get the required quantity without wasting any excess.
This cream is a semisolid preparation. It has a semi-solid consistency for easy, targeted application on the skin.
This cream should be applied on the skin as per the instructions given by your healthcare provider. Make sure to wash and dry your hands before and after applying the cream.
If you miss a dose, apply it as soon as you remember. If it's near the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Avoid applying extra cream to make up for a missed dose.
Like all medications, there may be potential side effects from the use of this cream. If you experience any unusual symptoms, consult your healthcare provider immediately.
Let your healthcare provider know about any other medications or supplements you are taking. They can decide if it is safe for you to use this cream alongside your other treatments.
Certain types of skin may react differently to the ingredients in the cream. Always do a patch test or consult with your healthcare provider before starting any new medication, including topicals.
Store the product in a cool, dry area away from direct sunlight. Always check the label for specific storage instructions.
Do not apply this cream to open wounds or sensitive areas. Avoid contact with your eyes, nose, and mouth. Always follow the dosing schedule and instructions provided by your healthcare provider.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
