Check out our most popular compounded medications! Get Started
The DHEA 0.5% Vaginal Cream is a semisolid formulation specifically compounded for the treatment of certain gynecological conditions. This cream is dispensed in a tube to facilitate convenient and precise application within the vaginal area. The active ingredient, DHEA (dehydroepiandrosterone), is utilized for its potential benefits in managing symptoms of vulvovaginal atrophy, often associated with menopause. Additionally, it may be prescribed to address sexual dysfunction and to support the overall health of vaginal tissues. The cream's composition is designed to ensure that DHEA is delivered directly to the affected area, providing targeted relief and therapeutic effects.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
DHEA, or dehydroepiandrosterone, is a naturally occurring hormone that serves as a precursor to other sex hormones such as estrogen and testosterone. As a 0.5% vaginal cream, this formulation is specifically compounded to address issues related to vaginal atrophy, which often occurs during menopause due to the decline in estrogen levels. The cream is designed to be applied directly to the vaginal area, providing localized relief from symptoms such as dryness, itching, burning, and pain during intercourse. The semisolid consistency ensures that the cream stays in place, allowing for optimal absorption of DHEA into the vaginal tissues.
The DHEA in the cream is metabolized by local tissues into estrogen and androgens, which can help replenish the levels of these hormones in the vaginal area. This can lead to an improvement in the thickness and elasticity of the vaginal walls, increased natural lubrication, and an overall reduction in discomfort. By targeting the area of concern directly, the cream minimizes systemic absorption, which can be beneficial for patients who are unable or unwilling to undergo systemic hormone replacement therapy.
For patients, it is important to understand that this treatment is intended for regular use as directed by a healthcare provider. It is also crucial to follow the application instructions carefully to ensure proper dosing and to minimize the risk of side effects. For prescribers, it is essential to consider the patient's overall hormone profile and medical history before recommending this formulation, as well as to monitor the patient's response to therapy and adjust the treatment as necessary.
Bayview Pharmacy's team of compounding pharmacists is dedicated to providing high-quality, customized medications to meet the unique needs of each patient. If you have any questions about DHEA 0.5% Vaginal Cream or its suitability for treating specific gynecological conditions, please do not hesitate to reach out to us. We are here to support both patients and healthcare providers with expert advice and comprehensive care.
Dehydroepiandrosterone (DHEA) is an endogenous steroid hormone that serves as a precursor to androgens and estrogens. DHEA has been used in various formulations, including vaginal creams, to address issues such as vaginal atrophy, dryness, and possibly sexual dysfunction. When considering the use of DHEA 0.5% Vaginal Cream, it is important to be aware of potential drug interactions that may affect the safety and efficacy of the treatment.
Firstly, patients should be advised that DHEA is metabolized into active sex hormones, and therefore, it may interact with hormone-sensitive conditions and medications. For example, women with a history of hormone-sensitive cancers, such as breast or endometrial cancer, should use DHEA with caution, as it may theoretically influence hormone levels and tumor growth. Additionally, concurrent use of DHEA with other hormonal therapies, such as estrogen or testosterone, may alter the effects of these medications and potentially increase the risk of side effects.
Secondly, DHEA may interact with medications that are metabolized by the liver enzymes, particularly the cytochrome P450 system. Drugs that are substrates, inhibitors, or inducers of these enzymes could potentially affect the metabolism of DHEA, leading to altered blood levels of either DHEA or the concomitant medication. This could necessitate dosage adjustments or close monitoring by a healthcare provider.
Thirdly, the use of DHEA may influence insulin sensitivity and glucose metabolism. Patients with diabetes or those taking antidiabetic medications should be monitored for changes in blood glucose levels when initiating or discontinuing DHEA therapy. Adjustments to antidiabetic medication dosages may be required.
It is also important to consider the potential for DHEA to interact with over-the-counter supplements and herbal products. For instance, supplements that have hormonal activity, such as soy isoflavones or red clover, may have additive or antagonistic effects when used with DHEA.
Lastly, patients should be counseled to avoid the use of DHEA with other vaginal products unless directed by a healthcare provider, as there may be interactions that could alter the pH of the vagina or the absorption of the medication.
Given the complexity of potential drug interactions with DHEA 0.5% Vaginal Cream, it is crucial for patients and prescribers to review all current medications, including prescription drugs, over-the-counter medications, and dietary supplements, with a healthcare professional before starting treatment. If you have any questions or concerns regarding the use of DHEA 0.5% Vaginal Cream or its interactions with other medications, please reach out to us at Bayview Pharmacy for further assistance.
DHEA, or dehydroepiandrosterone, is a naturally occurring hormone produced by the adrenal glands. It serves as a precursor to male and female sex hormones, including estrogen and testosterone. As women age, particularly during and after menopause, the levels of DHEA and its derivatives in the body decrease, which can lead to various symptoms and health issues, such as vaginal atrophy, dryness, and inflammation, as well as a decrease in sexual function. DHEA 0.5% Vaginal Cream is a hormone replacement therapy designed to address these issues by delivering a small, controlled dose of DHEA directly to the vaginal tissue.
The formulation of DHEA 0.5% Vaginal Cream is specifically designed to be applied intravaginally, where it is absorbed through the vaginal mucosa. Once absorbed, DHEA is converted by local enzymes into active sex hormones, such as estrogen and testosterone, which can help to replenish the levels of these hormones in the vaginal tissue. This localized hormone delivery system is beneficial because it minimizes systemic absorption and reduces the potential for systemic side effects that can occur with oral hormone replacement therapies.
The therapeutic effects of DHEA 0.5% Vaginal Cream include the restoration of the normal physiology of the vaginal tissue, which can lead to an improvement in symptoms such as dryness, itching, and pain during intercourse. Additionally, it can help to maintain the health of the vaginal mucosa, potentially reducing the risk of urinary tract infections and other vaginal infections. The cream is also thought to have a beneficial effect on sexual function by improving libido and sexual arousal, which can be adversely affected by the decrease in sex hormone levels associated with menopause.
The semisolid formulation of the cream allows for easy and precise application. It is typically dispensed in a tube, which can be used to apply the cream directly to the vaginal area. Patients are usually instructed to use a specific amount of cream, which is measured using an applicator provided with the medication. This ensures that the correct dose is delivered each time the cream is used.
Women with a history of hormone-sensitive cancers, liver disease, or those who are pregnant or breastfeeding should not use this medication. Additionally, patients should be monitored for any side effects, and the treatment should be tailored to the individual's response and needs.
If you have any questions about DHEA 0.5% Vaginal Cream or its use in treating specific gynecological conditions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to make informed decisions about your health care.
DHEA 0.5% Vaginal Cream is used to deliver dehydroepiandrosterone (DHEA) locally within the vaginal area to help with specific gynecological conditions. This can include treating symptoms of vaginal atrophy, dryness, irritation, or pain during sexual activity that are often associated with menopause or hormonal changes.
To apply DHEA 0.5% Vaginal Cream, wash your hands thoroughly and follow the dosage instructions provided by your healthcare provider. Squeeze out the prescribed amount of cream onto your applicator, if one is provided, and gently insert it into the vagina as directed. Otherwise, use your finger to apply the cream to the affected area.
The frequency of application will depend on your condition and the instructions given by your healthcare provider. Do not use more than what has been prescribed.
Side effects from DHEA 0.5% Vaginal Cream can occur, although not everyone will experience them. Possible side effects include vaginal discharge, local irritation, itching, or a burning sensation. If you experience any severe side effects or signs of an allergic reaction, contact your healthcare professional immediately.
DHEA is considered a hormonal precursor, which means it can be converted into more potent hormones like estrogen and testosterone in the body. While it is not the same as traditional HRT, it can exert similar effects by influencing hormone levels in the tissue where it is applied. Discuss with your healthcare provider to understand how this affects your treatment.
It is generally advisable to avoid using DHEA 0.5% Vaginal Cream during menstruation. However, consult your healthcare provider for specific instructions tailored to your treatment plan.
DHEA 0.5% Vaginal Cream may actually improve sexual activity for some by alleviating discomfort due to vaginal dryness or atrophy. It is usually recommended to wait a certain amount of time after application before engaging in sexual activity; consult your healthcare provider for guidance.
Patients with a history of hormone-sensitive cancers should discuss the use of DHEA 0.5% Vaginal Cream with their healthcare provider, as this treatment has the potential to influence hormone levels.
Store DHEA 0.5% Vaginal Cream at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not freeze the cream, and discard it if it becomes discolored or if the expiration date has passed.
Before using other vaginal products in conjunction with DHEA 0.5% Vaginal Cream, it is important to discuss with your healthcare provider to ensure compatibility and to avoid potential interactions.
If you miss a dose, use it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and proceed with your regular dosing schedule. Do not double the dose to catch up.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Insert/apply intravaginally
