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Dexamethasone 5 mg/ml Transdermal Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Dexamethasone

The Dexamethasone 5 mg/ml Transdermal Gel is a semisolid formulation designed for targeted application on the skin. This gel is dispensed through a pump mechanism, which allows for easy and precise dosing. The consistency of the gel ensures that the active ingredient, dexamethasone, is delivered in a controlled manner to the affected area. Dexamethasone is a potent corticosteroid known for its anti-inflammatory and immunosuppressant properties. This transdermal gel is commonly used in the treatment of localized inflammatory conditions such as dermatitis, eczema, and psoriasis. Additionally, it may be utilized for the management of certain autoimmune disorders where localized treatment is indicated. The transdermal route provides the advantage of minimizing systemic exposure and potential side effects associated with oral corticosteroids.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

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Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Dexamethasone
Topical Gel
654e8df272c551aa7affc20d
Service area

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Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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Dexamethasone 5 mg/ml Transdermal Gel is a specialized medication formulated for transdermal delivery, providing a targeted approach to treatment. This semisolid formulation is designed to be dispensed through a pump mechanism, which ensures ease of use and precise dosing. The gel consistency allows for smooth application on the skin, facilitating the absorption of the active ingredient, dexamethasone, directly into the affected area. This method of delivery is particularly beneficial for patients who may have difficulties with oral administration or for conditions where localized treatment is preferred.

Dexamethasone is a potent corticosteroid with anti-inflammatory and immunosuppressant properties. In this transdermal gel form, it is used to treat a variety of localized inflammatory conditions such as dermatitis, eczema, and certain types of psoriasis. By applying the gel directly to the skin, the medication can act at the site of inflammation, reducing symptoms such as redness, swelling, and itching. This localized approach helps to minimize systemic absorption and potential side effects associated with oral corticosteroids.

For prescribers, it is important to note that the concentration of dexamethasone in this formulation is 5 mg/ml, which should be taken into account when determining the appropriate dose for the patient. The pump mechanism can aid in delivering a consistent dose with each application, but the total amount applied will depend on the size of the affected area and the severity of the condition. It is also crucial to instruct patients on proper application techniques to ensure optimal efficacy of the medication.

Patients should be advised to apply the gel as directed by their healthcare provider, typically to clean, dry skin. They should be informed about the potential for systemic absorption and the importance of using the medication only on the prescribed area. Side effects can include local skin reactions such as burning, itching, or irritation. Long-term use or application over large areas should be monitored due to the risk of systemic corticosteroid effects.

Bayview Pharmacy is committed to providing high-quality, customized medications to meet the unique needs of each patient. Our team of compounding pharmacists is available to answer any questions and provide guidance on the use of Dexamethasone 5 mg/ml Transdermal Gel. We encourage both patients and prescribers to reach out to us for further information or assistance with this formulation.

Drug Interactions

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The Dexamethasone 5 mg/ml Transdermal Gel is a potent corticosteroid formulation designed for topical application. When considering drug interactions, it is important to note that while systemic absorption of dexamethasone through the skin is generally lower than oral administration, interactions can still occur, particularly with prolonged use or over large surface areas. Patients should be advised to inform their healthcare providers of all medications they are taking, including prescription drugs, over-the-counter medications, herbal supplements, and vitamins.

Concomitant use of dexamethasone with other corticosteroids, whether topical, oral, or inhaled, may increase the risk of systemic corticosteroid side effects such as Cushing's syndrome and adrenal suppression. Caution is advised when using other medications that can also suppress the immune system, such as cyclosporine or tacrolimus, as this may increase the likelihood of infections.

Nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk of gastrointestinal side effects when used with systemic corticosteroids. Although the risk is less with topical application, caution is still advised, especially in patients with a history of gastrointestinal ulcers or bleeding. Patients taking anticoagulants like warfarin should be monitored closely, as corticosteroids can alter the effects of these medications, potentially leading to an increased risk of bleeding.

Diabetes medications may require dosage adjustments since corticosteroids can affect blood glucose levels. Patients with diabetes should regularly monitor their blood sugar and consult their healthcare provider for potential medication adjustments. Enzyme inducers, such as phenytoin, phenobarbital, and rifampin, may decrease the plasma concentration of corticosteroids, potentially reducing their efficacy. Conversely, enzyme inhibitors like ketoconazole can increase plasma corticosteroid levels, leading to enhanced effects and potential side effects.

Live or live-attenuated vaccines should be used with caution in patients receiving immunosuppressive doses of corticosteroids, as the desired immune response may not be achieved. Additionally, the use of dexamethasone with diuretics, particularly potassium-depleting agents, may exacerbate electrolyte imbalances, especially hypokalemia.

It is also important to consider the potential for skin irritation or allergic reactions when using topical formulations. Patients should be instructed to apply the gel to clean, intact skin and to avoid contact with open wounds or mucous membranes. If signs of skin irritation or hypersensitivity occur, use of the product should be discontinued and medical advice sought.

This transdermal gel is indicated for the treatment of various inflammatory and autoimmune conditions where corticosteroids are beneficial. It can be used for localized treatment of conditions such as dermatitis, eczema, and psoriasis, providing anti-inflammatory and immunosuppressive effects directly to the affected area. The precise dosing pump mechanism allows for consistent dosing, which is critical for managing the condition effectively while minimizing the risk of systemic side effects.

For any further questions or concerns regarding the use of Dexamethasone 5 mg/ml Transdermal Gel, or to report any adverse reactions or interactions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is committed to providing comprehensive support to both patients and prescribers to ensure appropriate treatment.

How Does it Work

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The Dexamethasone 5 mg/ml Transdermal Gel is a specialized medication designed for topical application. This semisolid formulation is dispensed through a pump mechanism, which ensures that patients can apply a consistent and precise dose of the medication directly to the affected area of the skin. The gel base is specifically formulated to facilitate the penetration of dexamethasone through the skin barrier, allowing for localized anti-inflammatory and immunosuppressant effects.

Dexamethasone is a potent synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. When applied to the skin, it works by mimicking the actions of cortisol, a natural hormone produced by the adrenal glands, which modulates the body's inflammatory response. Dexamethasone in the transdermal gel binds to glucocorticoid receptors within the cells, leading to the suppression of the release of pro-inflammatory cytokines and other mediators of inflammation. This results in a decrease in swelling, redness, and pain in the treated area.

This transdermal gel formulation is particularly useful for treating localized inflammatory conditions such as dermatitis, eczema, or psoriasis, where systemic side effects of oral corticosteroids may be a concern. By delivering the medication directly to the site of inflammation, higher concentrations of the drug can be achieved at the target tissue, while minimizing systemic absorption and potential side effects. Additionally, the gel formulation provides a cooling and soothing effect upon application, which can be beneficial for irritated or inflamed skin.

It is important for both patients and prescribers to understand that while the transdermal delivery system offers advantages in terms of targeted therapy and reduced systemic exposure, it is still essential to use the medication as directed to avoid overuse or misuse, which could lead to skin atrophy or other local adverse effects. The pump mechanism of the gel dispenser aids in delivering a measured dose, but patients should be instructed on the correct amount to apply and the frequency of application as prescribed by their healthcare provider.

For any questions regarding the Dexamethasone 5 mg/ml Transdermal Gel, its application, or its suitability for treating specific dermatological conditions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and appropriate use of this medication.

Frequently Asked Questions

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What is Dexamethasone 5 mg/ml Transdermal Gel?

Dexamethasone 5 mg/ml Transdermal Gel is a medicated gel containing the corticosteroid dexamethasone at a concentration of 5 milligrams per milliliter. The gel is formulated for transdermal delivery of the medication through the skin, providing targeted treatment for various conditions as prescribed by a healthcare provider.

How is the gel applied to the skin?

The gel is applied to the skin using a pump mechanism that dispenses an exact amount of the product. To use, press the pump to dispense the medication, then spread the gel lightly over the affected area of skin as directed by your physician.

What conditions can be treated with Dexamethasone Transdermal Gel?

Dexamethasone Transdermal Gel can be used to treat localized skin conditions or inflammations that respond to corticosteroids. However, its use should be based on a doctor's prescription and it may be indicated for conditions such as psoriasis, eczema, or dermatitis.

Can Dexamethasone Transdermal Gel produce side effects?

Yes, like all medications, the gel can produce side effects, although not everyone will experience them. Common side effects might include skin irritation at the application site. Systemic absorption of dexamethasone can also cause side effects related to corticosteroid use, particularly with long-term use or over a large area of skin.

How often should I use the Dexamethasone Transdermal Gel?

The frequency of use for the Dexamethasone Transdermal Gel should be determined by your healthcare provider. It's essential to follow their instructions and not to apply more frequently than recommended to avoid the risk of side effects.

Should I cover the area after applying the gel?

Unless instructed by your healthcare provider, you generally should not cover the treated area with bandages or dressings. Covering the area can increase the absorption of the medication into the bloodstream and potentially increase the risk of side effects.

What should I do if I miss a dose?

If you miss a dose of Dexamethasone Transdermal Gel, apply it as soon as you remember, unless it is close to the time for your next application. In that case, skip the missed dose and proceed with your regular dosing schedule. Do not double the dose to make up for the missed one.

How should I store Dexamethasone Transdermal Gel?

The gel should be stored at room temperature, away from heat and direct light, and kept out of reach of children. Make sure the pump mechanism is securely closed to prevent drying out of the gel.

Can I use other medications or skincare products with this gel?

You should consult your healthcare provider before using other medications or skincare products in conjunction with Dexamethasone Transdermal Gel. Some products may alter the effectiveness of the gel or increase the risk of side effects.

What precautions should I take when using Dexamethasone Transdermal Gel?

Avoid getting the medication in your eyes, nose, or mouth. If contact occurs, rinse thoroughly with water. Additionally, you should not use the gel on skin areas that have cuts, infections, or sores unless directed by your doctor. Always follow the specific precautions and guidance provided by your healthcare provider.

Can I use Dexamethasone Transdermal Gel if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should use Dexamethasone Transdermal Gel only if it is clearly necessary and prescribed by your doctor. As with all medications during pregnancy and lactation, the potential benefits must be weighed against the potential risks to the fetus or infant.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Dexamethasone 5 mg/ml Transdermal Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Twice daily