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The Dexamethasone Sodium Phosphate 0.528% Topical Gel is a semisolid formulation designed for ease of use and precise dosing through a pump mechanism. This gel-like medication is intended for topical application on the skin, where it delivers its potent anti-inflammatory and immunosuppressant effects directly to the affected area. It is commonly used in the treatment of various dermatological conditions, including but not limited to eczema, psoriasis, and dermatitis. Additionally, it may be prescribed for localized inflammatory conditions such as bursitis, tenosynovitis, and certain arthritic ailments. The gel's consistency ensures that the active ingredient is absorbed effectively at the site of application, providing targeted relief from inflammation and associated symptoms.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Dexamethasone Sodium Phosphate 0.528% Topical Gel is a specially compounded medication designed to deliver a potent corticosteroid directly to the affected area of the skin. This semisolid formulation is dispensed through a pump mechanism, which ensures that patients can apply a consistent and precise dose with each use. The gel base provides a soothing and cooling effect upon application, enhancing patient comfort while allowing for the gradual release and absorption of the active ingredient, dexamethasone sodium phosphate.
Dexamethasone is a synthetic adrenocortical steroid with potent anti-inflammatory and immunosuppressive properties. When applied topically, it can effectively reduce inflammation, relieve itching, and decrease redness and swelling associated with various dermatological conditions. This makes it an appropriate treatment for a range of skin disorders, including but not limited to eczema, psoriasis, contact dermatitis, and certain autoimmune blistering diseases. The 0.528% concentration has been carefully selected to provide an optimal balance between efficacy and safety, minimizing the potential for systemic absorption and side effects when used as directed.
For prescribers, it is important to note that the use of topical corticosteroids, such as Dexamethasone Sodium Phosphate Gel, should be tailored to the individual patient's condition, with consideration given to the severity of inflammation and the size of the affected area. Treatment duration should be limited to the shortest period necessary to achieve the desired therapeutic outcome, and patients should be monitored for potential side effects, including skin atrophy, telangiectasia, and hypothalamic-pituitary-adrenal (HPA) axis suppression with prolonged use.
Patients should be instructed on how to use the pump and apply the gel correctly. A thin layer of the gel should be gently spread over the affected area, usually one or two times daily or as directed by the healthcare provider. It is essential to wash hands before and after application unless the hands are the treated area. Patients should be advised to avoid occlusive dressings unless recommended by their healthcare provider, as this may increase systemic absorption.
Bayview Pharmacy is committed to providing high-quality, customized medications to meet the unique needs of each patient. Our team of compounding pharmacists is available to answer any questions and provide additional information to ensure the safe and appropriate use of Dexamethasone Sodium Phosphate 0.528% Topical Gel. If you have any questions or require further assistance, please do not hesitate to reach out to us.
Dexamethasone Sodium Phosphate is a potent corticosteroid with anti-inflammatory and immunosuppressive properties. When applied topically as a 0.528% gel, it is used to treat various inflammatory skin conditions, such as eczema, psoriasis, and dermatitis. It is important to consider potential drug interactions when using this formulation to ensure safety and efficacy.
Concomitant use of other topical corticosteroids should be approached with caution, as this may increase the systemic absorption of corticosteroids, potentially leading to Cushing's syndrome and other corticosteroid-related adverse effects. Patients should inform their healthcare provider of all topical medications they are currently using before starting treatment with Dexamethasone Sodium Phosphate gel.
Patients using Dexamethasone Sodium Phosphate gel should also be cautious when applying other topical preparations, such as lotions, creams, or ointments, especially if they contain occlusive components. Occlusive dressings can increase the percutaneous absorption of topical corticosteroids, potentially leading to an increased risk of systemic side effects. It is advisable to consult with a healthcare provider before combining such treatments.
Systemic absorption of dexamethasone may interact with certain oral medications. For example, the efficacy of antidiabetic drugs may be reduced, necessitating adjustments in dosing. Additionally, patients taking nonsteroidal anti-inflammatory drugs (NSAIDs) may have an increased risk of gastrointestinal side effects, and those on anticoagulants like warfarin may require closer monitoring of their coagulation parameters.
Enzyme inducers, such as phenytoin, phenobarbital, and rifampin, may decrease the plasma concentration of dexamethasone, potentially reducing its therapeutic effect. Conversely, enzyme inhibitors like ketoconazole can increase plasma concentrations of corticosteroids, leading to enhanced effects and potential side effects. It is essential to monitor patients for signs of corticosteroid toxicity if they are taking enzyme inhibitors.
Live or live-attenuated vaccines should be used with caution in patients receiving immunosuppressive doses of corticosteroids, as the desired immune response may not be achieved, and there may be an increased risk of adverse reactions from the vaccine.
It is crucial for patients to inform their healthcare providers of all medications they are taking, including over-the-counter drugs, herbal supplements, and vitamins, to avoid potential drug interactions. If you have any questions or concerns regarding the use of Dexamethasone Sodium Phosphate 0.528% Topical Gel or its interactions with other medications, please reach out to us at Bayview Pharmacy for further assistance.
The Dexamethasone Sodium Phosphate 0.528% Topical Gel is a specially designed medication that delivers a potent corticosteroid directly to the affected area of the skin. Dexamethasone is a synthetic adrenocortical steroid known for its anti-inflammatory and immunosuppressive properties. When applied topically, it works by inhibiting the release of substances in the body that cause inflammation. This reduction in inflammatory mediators, such as prostaglandins and leukotrienes, leads to decreased swelling, redness, and pain in the treated area.
The gel formulation is a semisolid dosage form that allows for the medication to be evenly distributed across the skin's surface. The 0.528% concentration ensures that a sufficient amount of dexamethasone is available to exert its therapeutic effect. The gel base is designed to enhance the penetration of the active drug through the skin, allowing for localized treatment of the affected area. This is particularly beneficial in dermatological conditions where systemic effects of steroids are to be minimized.
Upon application, the gel creates a protective barrier that not only delivers the medication but also hydrates the skin. The pump mechanism of the container dispenses a measured dose of the gel, which helps in maintaining consistency in the amount of medication applied, ensuring accurate dosing and maximizing the therapeutic effect while minimizing the risk of side effects.
This formulation is particularly useful in treating a variety of dermatological conditions such as eczema, psoriasis, and dermatitis, where inflammation is a primary concern. By applying the gel directly to the lesion, the active ingredient can act swiftly to alleviate symptoms such as itching, redness, and swelling. Additionally, it may be used in the management of localized inflammatory conditions of the joints and soft tissues, such as bursitis or tenosynovitis, where its anti-inflammatory action can help to reduce pain and improve mobility.
It is important for both patients and prescribers to understand that while dexamethasone provides relief from symptoms, it is not a cure for the underlying condition. Long-term use should be avoided due to the potential for systemic absorption and the associated side effects of corticosteroids. Patients should follow the prescribed dosage and duration of treatment closely and report any adverse effects to their healthcare provider. For any questions or concerns regarding the use of Dexamethasone Sodium Phosphate 0.528% Topical Gel, please reach out to us at Bayview Pharmacy for further assistance.
This medication is used to reduce inflammation and relieve pain in certain skin conditions. It is a corticosteroid with potent anti-inflammatory properties.
Clean and dry the affected skin area. Then use the pump mechanism to dispense a small amount of the gel onto your hand or directly onto the skin and apply a thin film over the affected area, gently rubbing it in as directed by your healthcare provider.
No, dexamethasone sodium phosphate is a prescription medication, and you would need a prescription from a healthcare provider to purchase this topical gel.
The frequency of use for this medication will be determined by your healthcare provider based on your condition and response to treatment. It is important to follow their instructions carefully.
Yes, like all medications, Dexamethasone Sodium Phosphate Topical Gel may cause side effects, including skin irritation, dryness, or redness at the application site. If you notice more severe side effects like skin thinning or stretch marks, contact your doctor immediately.
You should consult your healthcare provider before using other topical products in conjunction with this medication, as there may be a risk of interactions or increased side effects.
If you miss a dose, apply it as soon as you remember. However, if it is near the time for your next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
This medication may be prescribed for children; however, children are more sensitive to the effects of corticosteroids. It's important that it is used under the supervision and direction of a pediatrician or dermatologist.
Store this medication at room temperature away from light and moisture. Do not freeze the gel, and keep it out of reach of children and pets.
While overdose is unlikely when using a topical gel as prescribed, if someone has used excessive amounts and has serious symptoms such as passing out or difficulty breathing, call emergency services right away.
Though it is unlikely to affect systemic medications due to its topical application, you should still inform your healthcare provider of all medications you are currently taking, including prescription, over-the-counter medicines, and herbal supplements to avoid any potential interactions.
It is generally best to avoid applying other products to the treated area without checking with your healthcare provider first. If permitted, wait for the gel to dry before applying other substances over it.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
