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Description: This oral liquid formulation contains Dibasic Sodium Phosphate 398 mg and Monobasic Sodium Phosphate 1102 mg per 10 mL. It is a specifically formulated liquid medication intended for oral administration, providing a convenient and easily ingested dosage form for accurate delivery of medication. This solution is particularly beneficial for patients who find swallowing solid dosage forms challenging, including pediatric and geriatric populations. The combination of dibasic and monobasic sodium phosphate is commonly used to treat constipation and to prepare the bowel for medical procedures.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
The formulation, consisting of 398 mg of Dibasic Sodium Phosphate and 1102 mg of Monobasic Sodium Phosphate per 10 mL, is designed to provide a balanced solution for the management of various conditions. This oral liquid is particularly beneficial for patients who have difficulty swallowing pills, such as children and the elderly, or for those who require precise dosage adjustments.
The combination of Dibasic Sodium Phosphate and Monobasic Sodium Phosphate in this formulation acts as a laxative and is commonly used to treat constipation. It works by drawing water into the bowel, which helps to soften stools and stimulate bowel movements. This action can be helpful in preparing patients for certain medical procedures that require a clear bowel, such as colonoscopies. Additionally, the phosphate salts in the medication can help to replenish low levels of phosphate in the blood, a condition known as hypophosphatemia. This can occur in various disease states, including malnutrition, rapid refeeding in those who are malnourished, and in some endocrine disorders.
It is important for patients and prescribers to be aware that the use of this medication should be under medical supervision, especially in individuals with kidney disease, electrolyte imbalances, or heart conditions, as the sodium and phosphate ions can affect fluid and electrolyte balance. The dosage and duration of treatment should be tailored to the individual patient's needs and medical condition, and it is essential to follow the prescribed regimen to avoid potential side effects or complications.
For optimal results, patients should take this medication as directed by their healthcare provider. It is also important to maintain adequate hydration while using this medication. If you have any questions or concerns about this formulation or its use in treating specific disease states, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of expert compounding pharmacists is here to provide guidance and support to ensure the safe and appropriate use of this medication.
The oral liquid formulation containing Dibasic Sodium Phosphate 398 mg and Monobasic Sodium Phosphate 1102 mg per 10 mL is primarily used as a laxative for bowel cleansing prior to medical procedures such as colonoscopy. It is important to consider potential drug interactions when administering this medication, as it can affect the absorption, distribution, metabolism, or excretion of other drugs.
One significant interaction is with medications that may affect electrolyte balance, such as diuretics, corticosteroids, and angiotensin-converting enzyme (ACE) inhibitors. The use of sodium phosphate solutions can lead to alterations in electrolyte levels, particularly hyperphosphatemia, hypocalcemia, hypernatremia, and hypokalemia. Patients on such medications should be monitored closely for signs of electrolyte imbalance.
Additionally, the absorption of certain drugs may be reduced when taken concurrently with sodium phosphate solutions. This is particularly relevant for medications that require a specific gastric pH for optimal absorption, such as ketoconazole, itraconazole, and certain protease inhibitors. To minimize this interaction, it is advisable to administer these medications at least 1 to 2 hours before or after the intake of the sodium phosphate solution.
Patients taking tetracycline or fluoroquinolone antibiotics should also be cautious, as phosphate can bind to these drugs in the gastrointestinal tract, reducing their effectiveness. A similar interval as mentioned above should be observed when administering these antibiotics with sodium phosphate solutions.
Calcium-based antacids or supplements may interact with sodium phosphate solutions, leading to the formation of insoluble calcium phosphate complexes, which can reduce the efficacy of both the phosphate solution and the calcium supplement. Patients should avoid taking calcium supplements or antacids within a short time frame of taking the sodium phosphate solution.
It is also important to note that the use of sodium phosphate solutions can exacerbate dehydration. Therefore, patients taking medications that have a diuretic effect, including nonsteroidal anti-inflammatory drugs (NSAIDs) and certain antihypertensive medications, should be adequately hydrated to prevent renal complications.
Lastly, patients with pre-existing renal insufficiency or those taking nephrotoxic medications, such as aminoglycosides, amphotericin B, vancomycin, or nonsteroidal anti-inflammatory drugs (NSAIDs), should use sodium phosphate solutions with caution due to the increased risk of acute phosphate nephropathy.
It is crucial for prescribers to review the patient's medication profile for potential interactions before prescribing this sodium phosphate solution. Patients should be advised to inform their healthcare provider of all medications, supplements, and over-the-counter drugs they are taking to ensure safe use of this formulation. If you have any questions or require further information regarding drug interactions with this formulation, please reach out to us at Bayview Pharmacy for assistance.
The oral liquid formulation containing Dibasic Sodium Phosphate 398 mg and Monobasic Sodium Phosphate 1102 mg per 10 mL is designed to deliver a precise dose of sodium phosphate to the patient. This medication works by supplying the body with sodium and phosphate, which are essential electrolytes for various physiological functions. Phosphate is a key component of bone and teeth mineralization, cellular energy storage and transfer, and the regulation of acid-base balance in the body. Sodium helps to regulate blood pressure, blood volume, and pH levels, as well as playing a critical role in nerve and muscle function.
When ingested, this oral liquid formulation increases the phosphate and sodium levels in the blood. This can be particularly useful in treating conditions where phosphate levels are abnormally low, a condition known as hypophosphatemia. Hypophosphatemia can occur due to a variety of reasons, including malnutrition, rapid refeeding in malnourished patients, alcohol withdrawal, and certain medical conditions that affect the kidneys' ability to reabsorb phosphate. By providing a direct source of phosphate, this medication helps to correct the deficiency and mitigate the symptoms associated with low phosphate levels, such as muscle weakness, bone pain, and potentially impaired neurological function.
In addition to treating hypophosphatemia, this sodium phosphate oral solution can be used as a laxative to treat constipation or to prepare the bowel for medical procedures. As a laxative, the high osmotic effect of phosphate draws water into the intestine, increasing the fluid content in the bowels, which in turn stimulates bowel motility and results in defecation. This action can help to clear the bowel of stool, which is particularly useful before colonoscopies or other diagnostic tests that require a clear bowel.
It is important for patients and prescribers to be aware that the use of sodium phosphate solutions should be done with caution, especially in patients with kidney disease, heart failure, or those taking medications that may affect electrolyte levels. Overuse or misuse can lead to serious complications, such as electrolyte imbalances or kidney damage. Therefore, it is crucial to follow the prescribed dosage and to monitor for any signs of adverse effects. If you have any questions or concerns about this formulation or its use in treating specific disease states, please reach out to us at Bayview Pharmacy for further assistance.
This compounded medication is used for the treatment of patients with certain electrolyte imbalances, such as phosphate deficiencies, or for those requiring phosphate supplementation for specific medical reasons. It must be prescribed by a healthcare professional.
The medication should be taken orally as directed by your physician. It should be measured with an accurate medical dosing device and can be taken with or without food. Follow your physician's instructions regarding dosing intervals.
The liquid formulation is particularly beneficial for patients who have difficulty swallowing pills, such as children or elderly patients, or for those who require precise dosage adjustments that are not possible with solid dosage forms.
It is important to follow your healthcare provider's instructions. Some medications can be mixed with certain foods or beverages to make them easier to ingest, but this could affect the medication's effectiveness. Always ask your healthcare provider or pharmacist before mixing.
This medication should be stored at room temperature, away from direct light, heat, and moisture. Keep the bottle tightly closed when not in use. Do not freeze the liquid, and keep it out of reach of children and pets.
If you miss a dose of your medication, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double doses to catch up, as this could lead to an overdose.
Side effects may include upset stomach, diarrhea, or a feeling of discomfort. If you experience more serious side effects such as confusion, weakness, irregular heartbeat, or seizures, you should contact your healthcare provider immediately.
The safety of this medication during pregnancy or breastfeeding has not been fully established. It is important to consult your healthcare provider for advice if you are pregnant, planning to become pregnant, or are breastfeeding.
The onset of action can vary based on individual conditions and the specific reason for treatment. Your healthcare provider will be able to give you more information based on your particular medical situation.
This medication should not directly affect your ability to drive or operate heavy machinery. However, if you experience side effects that could impair your ability to perform these activities safely, such as dizziness or confusion, you should avoid them and consult your healthcare provider.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Take orally
