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The Diclofenac Sodium 3%/Fluconazole 3%/Itraconazole 3%/Terbinafine HCl 1% Topical Nail Liquid is a specialized compound designed to address a range of nail conditions. This potent antifungal and anti-inflammatory combination is ideal for the treatment of onychomycosis (fungal nail infections), providing a multi-faceted approach to eradicate the infection and reduce associated inflammation. By delivering the active ingredients directly to the affected area, this topical solution promotes healthy nail regeneration and restores the natural structure and appearance of the nails.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
The Diclofenac Sodium 3%/Fluconazole 3%/Itraconazole 3%/Terbinafine HCl 1% Topical Nail Liquid is a compounded medication specifically designed for the treatment of various nail conditions, including fungal infections, brittleness, and discoloration. This unique formulation combines the anti-inflammatory properties of Diclofenac Sodium with the antifungal benefits of Fluconazole, Itraconazole, and Terbinafine HCl to create a potent topical solution aimed at restoring nail health and appearance.
Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that helps to reduce pain and inflammation in the affected nail area. This can be particularly beneficial for patients experiencing discomfort due to nail damage or infection. Fluconazole and Itraconazole are both triazole antifungal agents that work by inhibiting the fungal cytochrome P450 enzyme, which is essential for the synthesis of ergosterol, a key component of fungal cell membranes. By disrupting this process, these medications effectively weaken the fungal cell structure, leading to the death of the fungal cells.
Terbinafine HCl is an allylamine antifungal that operates by a slightly different mechanism, primarily inhibiting the enzyme squalene epoxidase, which is also involved in the ergosterol synthesis pathway. This results in a deficiency of ergosterol and an accumulation of squalene within the fungal cell, leading to cell death.
The combination of these four active ingredients in a topical nail liquid allows for direct application to the affected nails, ensuring that the medication is delivered where it is needed most. This targeted approach helps to maximize the therapeutic effects while minimizing systemic absorption and potential side effects. The liquid formulation is designed to penetrate the nail plate and reach the site of infection, promoting healthy nail growth and improving the overall appearance of the nails.
This compounded medication is suitable for patients who have not responded to traditional treatments or who require a multi-faceted approach to tackle their nail condition. It is important for both patients and prescribers to understand that the effectiveness of this treatment depends on consistent application as directed, and it may take several months to see significant improvement due to the slow growth rate of nails.
As with any medication, there may be potential side effects, and it is essential to use this formulation under the guidance of a healthcare professional. If you have any questions or require further information about the Diclofenac Sodium 3%/Fluconazole 3%/Itraconazole 3%/Terbinafine HCl 1% Topical Nail Liquid, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide support and guidance to ensure the safe and appropriate use of this specialized medication.
The topical nail liquid formulation containing Diclofenac Sodium 3%, Fluconazole 3%, Itraconazole 3%, and Terbinafine HCl 1% is designed to treat various nail conditions, including fungal infections, brittleness, and discoloration. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that can help reduce inflammation and pain in the nail area. Fluconazole, Itraconazole, and Terbinafine are antifungal agents that work by inhibiting the growth of fungi, thereby treating and preventing fungal infections of the nail.
When using this topical nail liquid, it is important to consider potential drug interactions. Diclofenac, being an NSAID, may interact with other topical products that contain NSAIDs or corticosteroids, potentially leading to increased systemic absorption and side effects. It is advisable to avoid concurrent use with other topical preparations that contain these agents unless directed by a healthcare provider.
Fluconazole and Itraconazole are both azole antifungals and can have interactions with a variety of systemic medications due to their effects on cytochrome P450 enzymes. While systemic absorption of these agents when applied topically is expected to be minimal, caution is still advised. Patients should inform their healthcare provider of all systemic medications they are taking, including over-the-counter drugs and herbal supplements, to assess for potential interactions.
Terbinafine is an allylamine antifungal that may also interact with systemic medications metabolized by the liver. Again, while systemic absorption is low with topical application, patients should be aware of the potential for interactions and report all current medications to their healthcare provider.
It is also important to note that the use of multiple antifungal agents in combination may increase the risk of local irritation or contact dermatitis. Patients should be monitored for signs of local adverse effects, such as redness, itching, or burning, and should report any such symptoms to their healthcare provider.
Patients should avoid using occlusive dressings or wraps over the treated nails unless advised by a healthcare provider, as this may increase the absorption of the active ingredients and the risk of systemic side effects.
Lastly, alcohol or other nail cosmetic products may affect the efficacy of the medication and should be used with caution. The use of nail polish or other nail cosmetic products on the treated nails should be discussed with a healthcare provider.
If you have any questions or require further information regarding drug interactions or the appropriate use of this topical nail liquid formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure appropriate treatment of your nail conditions.
The Diclofenac Sodium 3%/Fluconazole 3%/Itraconazole 3%/Terbinafine HCl 1% Topical Nail Liquid is a specially compounded medication designed to treat a variety of nail conditions, including fungal infections, brittleness, and discoloration. This liquid formulation is applied directly to the nails, ensuring that the active ingredients are delivered to the site of infection or damage for maximum effectiveness.
Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing inflammation and pain in the affected area. When applied topically to the nails, it can help alleviate symptoms associated with swelling and tenderness, providing comfort and aiding in the healing process. This can be particularly beneficial in cases where the nail condition is causing discomfort or pain.
Fluconazole, Itraconazole, and Terbinafine HCl are antifungal agents that work by inhibiting the growth of fungi. Fluconazole and Itraconazole belong to the triazole class of antifungal drugs, which function by blocking the synthesis of ergosterol, a key component of fungal cell membranes. Without ergosterol, the fungal cells become weak and are unable to grow or replicate. Terbinafine HCl, on the other hand, is an allylamine antifungal that works by inhibiting an enzyme called squalene epoxidase, which is also involved in the synthesis of ergosterol. By disrupting this process, Terbinafine HCl causes the fungal cells to accumulate squalene, leading to cell death.
The combination of these antifungal agents in the formulation provides a broad spectrum of action against various types of fungi that can cause nail infections, such as dermatophytes, yeasts, and molds. By using a combination of different antifungal mechanisms, the likelihood of treating the infection effectively is increased, and the risk of the fungi developing resistance to the treatment is reduced.
This topical nail liquid is designed to penetrate the nail plate and reach the site of infection, providing a localized treatment that minimizes systemic absorption and potential side effects. The liquid formulation is also convenient for patients to apply and is formulated to adhere to the nail surface, allowing for prolonged contact with the nail and the underlying infected area.
For optimal results, patients should follow the application instructions provided by their healthcare provider, ensuring that the medication is applied consistently and for the full duration of the treatment course. It is important to note that nail infections can be persistent and may require several weeks or months of treatment to fully resolve.
If you have any questions about this formulation or how it can be used to treat specific nail conditions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to both patients and prescribers looking to use this specialized medication.
This compounded formulation is designed to treat nail conditions such as fungal infections, brittleness, or discoloration. It delivers a combination of medications directly to the affected nails to promote healthy nail growth and improve overall appearance.
Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce pain and inflammation. Fluconazole, Itraconazole, and Terbinafine HCl are antifungal agents that work by inhibiting the growth of fungi that cause nail infections, thus helping to clear up the infection.
Clean and dry the affected nails thoroughly before applying the medication. Using the applicator provided, apply a thin layer of the liquid to the entire surface of the affected nails and the skin immediately surrounding the nails. Allow the liquid to dry. Use the medication as directed by your healthcare provider.
The frequency of application will depend on the specifics of your condition and the instructions given by your healthcare provider. It is important to follow their guidance for the best results.
It is generally advised to avoid the use of nail polish or other nail cosmetic products on the treated nails, as they can prevent the medication from being absorbed properly. Consult with your healthcare provider for specific recommendations.
Common side effects may include local irritation, redness, or a burning sensation at the application site. If you experience severe side effects or signs of an allergic reaction, such as swelling or difficulty breathing, seek medical attention immediately.
Improvement in nail condition can vary depending on the severity and type of the nail issue being treated. It may take several weeks to months to see a noticeable difference. It's important to use the medication consistently and as directed to achieve the best results.
Consult your healthcare provider prior to using this medication if you are pregnant or breastfeeding to ensure it is safe for you and your baby.
If the liquid accidentally spreads onto the skin surrounding your nails, simply wipe it off with a tissue and wash the area with soap and water. If irritation occurs, contact your healthcare provider for advice.
Storing instructions for this medication will be provided by your pharmacy or healthcare provider. Generally, it should be kept at room temperature away from light and moisture. Do not refrigerate or freeze the medication unless directed otherwise.
If you miss a dose, apply it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up. Always follow the specific instructions given by your healthcare provider.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
