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Formulas

Enalapril Maleate 2.5 mg/0.1 mL Transdermal Gel (Vet)

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Enalapril Maleate

The Enalapril Maleate 2.5 mg/0.1 mL Transdermal Gel is a specialized veterinary medication designed for transdermal delivery. This semisolid formulation is dispensed through a user-friendly pump mechanism, which ensures easy and precise dosing. The gel's consistency allows for targeted application on the animal's skin, promoting efficient absorption of the active ingredient, Enalapril Maleate.

Enalapril Maleate is an angiotensin-converting enzyme (ACE) inhibitor that is commonly used to treat cardiovascular diseases in animals. This transdermal gel is specifically indicated for the management of congestive heart failure and hypertension in veterinary patients. Its transdermal route of administration is particularly beneficial for animals that are difficult to dose orally.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Enalapril Maleate
Topical Gel
655e9413aee9530ecd7888b9
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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Enalapril Maleate 2.5 mg/0.1 mL Transdermal Gel is a specialized veterinary medication designed for transdermal delivery, providing an alternative route of administration for pets who may not tolerate oral medications well. This semisolid formulation is dispensed through a pump mechanism, which ensures ease of use and precise dosing. The gel is applied topically, allowing for the active ingredient, Enalapril Maleate, to be absorbed through the skin. Enalapril is an angiotensin-converting enzyme (ACE) inhibitor that is commonly used in veterinary medicine to treat conditions such as hypertension and heart failure in animals.

The transdermal application of Enalapril Maleate offers a significant advantage for pets that are difficult to medicate orally. It bypasses the gastrointestinal tract, potentially reducing the risk of gastrointestinal side effects and improving patient compliance. The medication works by inhibiting the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, thereby leading to vasodilation and a reduction in blood pressure. This mechanism is beneficial in managing chronic heart failure, as it reduces the workload on the heart and improves cardiac output. Additionally, Enalapril can help to alleviate the symptoms associated with these conditions, such as difficulty breathing and fluid retention.

It is important for both patients and prescribers to understand that the use of Enalapril Maleate in a transdermal gel form should be based on a veterinarian's prescription and tailored to the individual needs of the pet. The effectiveness of the transdermal route should be monitored, and adjustments to the treatment regimen may be necessary based on the pet's response. As with any medication, there may be potential side effects, and these should be discussed with the veterinarian. If you have any questions or require further information about the Enalapril Maleate 2.5 mg/0.1 mL Transdermal Gel, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing the best possible care for your pet's unique needs.

Drug Interactions

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How Does it Work

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The Enalapril Maleate 2.5 mg/0.1 mL Transdermal Gel is a specialized veterinary medication designed to treat pets, particularly those who are unable to tolerate oral forms of medication due to various reasons such as difficulty swallowing or gastrointestinal side effects. Enalapril, the active ingredient in this formulation, is an angiotensin-converting enzyme (ACE) inhibitor. It works by blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, thereby leading to vasodilation, or the widening of blood vessels. This action reduces the blood pressure and decreases the workload on the heart. Consequently, enalapril is commonly used in the management of hypertension and heart failure in veterinary medicine.

The transdermal gel formulation allows for the medication to be absorbed through the skin, directly entering the systemic circulation. This route of administration can be particularly beneficial for animals that are stressed or difficult to treat with oral medications. The gel is designed to be applied to a small area of the skin, typically the inner ear flap or another area with less fur, which enhances the absorption of the drug. The semisolid consistency of the gel, combined with the pump mechanism, ensures a consistent and precise dose with each application, which is critical for maintaining the appropriate therapeutic levels of the medication.

When using the Enalapril Maleate Transdermal Gel, it is important to follow the dosing instructions provided by the veterinarian closely. The area of application should be clean and free of any barriers, such as dirt or excessive fur, to ensure proper absorption. It is also crucial to monitor the pet for any signs of adverse reactions or improvements in their condition, and to keep regular veterinary appointments for follow-up and adjustments to the treatment plan as necessary.

For prescribers considering this formulation, it is important to note that while transdermal absorption can be a convenient alternative to oral administration, the bioavailability and the rate of absorption can vary between animals. Therefore, close monitoring and possibly dose adjustments may be required to achieve the desired therapeutic effect. Additionally, prescribers should be aware of the potential for systemic side effects, as with any ACE inhibitor, which may include hypotension, renal dysfunction, or hyperkalemia.

If you have any questions about the Enalapril Maleate 2.5 mg/0.1 mL Transdermal Gel or its administration, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide support and guidance to ensure the safe and appropriate use of this medication for your veterinary patients.

Frequently Asked Questions

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What is Enalapril Maleate 2.5 mg/0.1 mL Transdermal Gel?

Enalapril Maleate Transdermal Gel is a prescription medication designed for veterinary use. It is a semisolid formulation containing 2.5 mg of Enalapril Maleate per 0.1 mL of gel, which is applied to an animal's skin to help treat conditions such as high blood pressure or heart failure. The gel is delivered via a pump mechanism that allows for precise dosing and targeted application.

How is this gel applied?

The Enalapril Maleate Transdermal Gel is applied to a small area of skin, usually on the inside of the animal's ear flap or another less hairy area as directed by the veterinarian. Use the pump to dispense the prescribed amount of gel, and then spread it evenly on the skin surface. It is important to wear gloves during application to avoid absorbing the medication through your skin.

Can this medication be used for both dogs and cats?

While Enalapril Maleate is commonly prescribed for both dogs and cats, the concentration and dosage may vary based on species, weight, and the condition being treated. Always consult with a veterinarian to ensure proper use for your specific pet and their health needs.

How often should the Enalapril Maleate gel be applied?

The frequency of application will depend on the individual pet's condition and the instructions provided by the veterinarian. It is important to follow the prescribed dosing schedule and not to alter it without consulting the vet.

Should the application area be prepared in any specific way?

Yes, it's recommended to clean and dry the area of skin where the gel will be applied. Remove any dirt, oil, or other substances to ensure the medication can be absorbed properly. Hair may also need to be clipped for optimal application.

What are the potential side effects of Enalapril Maleate gel?

As with any medication, side effects may occur. These can include localized skin irritation, vomiting, diarrhea, inappetence, or changes in blood pressure. If you observe any adverse effects in your pet, contact your veterinarian immediately.

What should I do if I miss applying a dose?

If you miss a dose, apply it as soon as you remember. However, if it's almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to catch up.

How should the Enalapril Maleate Transdermal Gel be stored?

Store the medication at room temperature, away from direct sunlight and heat. Keep the container tightly closed to prevent drying out. Always keep medications out of reach of children and pets.

Can I bathe my pet after applying the gel?

It's best to avoid bathing your pet immediately after application as it may wash off the medication before it's been fully absorbed. Consult with your veterinarian for guidance on an appropriate waiting period after application.

Is it safe for humans to come into contact with the Enalapril Maleate gel?

It is important to wear gloves when applying the gel to your pet, as it is not intended for human use and may be absorbed through the skin. If you come into contact with the medication, wash the area thoroughly with soap and water.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Enalapril Maleate 2.5 mg/0.1 mL Transdermal Gel (Vet)
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Twice daily