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The Estriol 1 mg/ml/Testosterone 0.25 mg/ml Vaginal Cream is a specialized semisolid formulation compounded for the treatment of specific gynecological conditions. This cream is designed to be easily dispensed from a tube for precise application within the vaginal area. The combination of estriol and testosterone in this cream is utilized to address symptoms associated with menopausal atrophic vaginitis, which includes vaginal dryness, itching, and irritation. Additionally, this formulation may be prescribed to help improve sexual function by addressing vaginal atrophy and the associated discomfort during intercourse. The dual hormone composition works synergistically to provide relief and promote the health of vaginal tissues.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Estriol 1 mg/ml/Testosterone 0.25 mg/ml Vaginal Cream is a specially compounded semisolid formulation designed for vaginal administration. This cream is dispensed in a tube, which allows for convenient and precise application. The formulation is intended to deliver the hormones estriol and testosterone directly to the vaginal area, where they exert their therapeutic effects. Estriol, a form of estrogen, is known for its efficacy in treating various symptoms associated with menopause, such as vaginal atrophy, dryness, irritation, and painful intercourse. It works by replenishing the estrogen that the body no longer produces at sufficient levels post-menopause, promoting the health and function of the vaginal tissue.
Testosterone, included at a concentration of 0.25 mg/ml, is a hormone that plays a role in sexual function and overall well-being. While testosterone is often thought of as a male hormone, it is also important for female health. In this formulation, testosterone may help to improve libido and sexual response, as well as contribute to the maintenance of healthy vaginal tissue. The combination of estriol and testosterone in this cream provides a synergistic effect, targeting multiple symptoms that can affect the vaginal area and sexual health.
This compounded vaginal cream is typically prescribed for women who are experiencing symptoms of hormonal imbalance or deficiencies, particularly those related to menopause or surgical menopause after procedures such as hysterectomy. It is important for patients to understand that this medication should be used under the guidance and prescription of a healthcare provider, who can determine the appropriate dosage and duration of treatment based on individual needs and health status.
For prescribers considering this formulation for their patients, it is essential to take into account the patient's medical history, current medications, and any contraindications that may exist for hormone therapy. Regular monitoring and follow-up appointments are recommended to assess the effectiveness of the treatment and to make any necessary adjustments. As with any medication, there may be potential side effects, and patients should be counseled on what to expect and when to seek medical attention.
If you have any questions or require further information about the Estriol 1 mg/ml/Testosterone 0.25 mg/ml Vaginal Cream, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to provide support and guidance to both patients and healthcare providers to ensure the safe and appropriate use of this customized medication.
The Estriol 1 mg/ml/Testosterone 0.25 mg/ml Vaginal Cream is a compounded medication designed to address specific gynecological conditions by delivering hormones directly to the vaginal area. Estriol, a form of estrogen, is often used to treat symptoms associated with menopause such as vaginal atrophy, dryness, and irritation. Testosterone, while typically considered a male hormone, plays a role in female sexual health and can be used to improve libido and sexual function in women. When using this formulation, it is important to consider potential drug interactions.
Estriol can interact with several types of medications. For instance, it may reduce the effectiveness of aromatase inhibitors (e.g., anastrozole, letrozole) which are used in the treatment of certain types of breast cancer. Concurrent use of estriol with thyroid hormone replacement therapy may necessitate adjustments in the dose of thyroid medication due to changes in thyroid-binding globulin levels. Additionally, estriol may alter the metabolism of drugs processed by liver enzymes, particularly those metabolized by the CYP3A4 enzyme system. This includes certain antifungal medications (e.g., ketoconazole), anticonvulsants (e.g., phenobarbital, carbamazepine), and some types of antibiotics (e.g., erythromycin).
Testosterone may also interact with a variety of medications. It can increase the anticoagulant effects of drugs like warfarin, necessitating close monitoring of prothrombin time or INR. Testosterone can affect blood glucose levels, which may require adjustments in insulin or oral diabetes medication for diabetic patients. Additionally, patients using corticosteroids or immunosuppressive drugs should be monitored for increased fluid retention and edema when testosterone is initiated.
It is also important to note that both estriol and testosterone can interact with substances such as alcohol and tobacco, which may affect hormone levels and the efficacy of the medication. Patients should be advised to discuss their use of over-the-counter medications, herbal supplements, and lifestyle factors with their healthcare provider to ensure safe and appropriate use of this vaginal cream.
Patients should be aware that this formulation is intended for vaginal use only and should not be applied to other areas of the body. They should also be instructed on proper application techniques to ensure the correct dose is administered. As with any medication, patients should be advised to report any unusual symptoms or side effects to their healthcare provider immediately.
For prescribers, it is crucial to review the patient's complete medication profile for potential interactions before prescribing this vaginal cream. Adjustments to therapy or additional monitoring may be necessary to safely use this formulation. If you have any questions or require further information regarding this compounded medication, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to support you and your patients.
The Estriol 1 mg/ml/Testosterone 0.25 mg/ml Vaginal Cream is a specially compounded formulation that combines two hormones, estriol and testosterone, in a cream base for vaginal application. Estriol is a form of estrogen, a female hormone that helps to maintain the health and function of the vaginal tissues. It is often used in hormone replacement therapy to alleviate symptoms of menopause such as vaginal dryness, itching, and burning. Estriol works by replenishing estrogen levels in the vaginal tissue, which can decline during menopause, leading to thinning and inflammation of the vaginal walls (atrophic vaginitis). By doing so, it helps to restore the natural thickness and elasticity of the vaginal mucosa, providing relief from discomfort and improving the overall health of the vaginal environment.
Testosterone, although typically considered a male hormone, plays a crucial role in female physiology as well. In this formulation, testosterone is included at a low concentration to help address issues such as decreased libido and sexual dysfunction, which can occur during menopause or as a result of other hormonal imbalances. Testosterone is believed to work by improving blood flow and sensitivity in the vaginal area, thereby enhancing sexual arousal and response. Additionally, it may contribute to the maintenance of healthy vaginal tissue.
The combination of estriol and testosterone in a cream allows for direct application to the affected area, ensuring that the medication is delivered where it is needed most. This localized approach minimizes systemic absorption and reduces the risk of side effects that can occur with oral hormone therapies. The cream is formulated to be easily spreadable, ensuring that it can coat the vaginal walls evenly for optimal absorption and effect. The semisolid nature of the cream also provides a soothing effect, which can be beneficial for those experiencing irritation or discomfort.
Patients are typically instructed to apply a measured dose of the cream to the vaginal area as prescribed by their healthcare provider. The cream is dispensed in a tube that allows for convenient and precise dosing. It is important for patients to follow the application instructions carefully to ensure the correct dosage and to maximize the therapeutic benefits of the medication.
This compounded vaginal cream is used to treat specific gynecological conditions such as atrophic vaginitis, which is associated with menopause, and sexual dysfunction, which can arise from hormonal imbalances. By addressing the underlying hormonal deficiencies, this formulation can alleviate symptoms and improve the quality of life for affected individuals.
If you have any questions about this formulation or how it works, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to provide guidance and support for both patients and prescribers considering the use of this specialized medication.
This compounded formulation is used to deliver specific doses of hormones directly to the vaginal area. It may be prescribed by healthcare providers to manage symptoms associated with hormonal deficiencies or imbalances, such as those related to menopause, and possibly to support local vaginal health. As with any medical treatment, it should be used under the guidance of a healthcare professional.
The cream should be applied according to the instructions provided by your healthcare provider. Typically, a specific amount of cream is applied using the finger or an applicator, ensuring precise dosing. The cream is usually applied inside the vagina, but detailed application instructions will be provided by your prescriber.
The frequency of use for Estriol/Testosterone vaginal cream will be determined by your healthcare provider based on your individual needs and condition. It’s important to follow their guidance strictly and not alter your dosing schedule without first consulting them.
As with any medication, there may be potential side effects. Common side effects can include vaginal irritation or itching, increased vaginal discharge, and potential systemic effects due to hormone absorption. If you experience any severe side effects or if you have concerns, contact your healthcare provider immediately.
This medication should not be used during pregnancy unless specifically directed by your healthcare provider. Hormonal treatments can have effects on fetal development, and the use of hormones during pregnancy is typically avoided unless deemed necessary.
Women with a history of hormone-sensitive cancers should consult their healthcare provider before using hormonal treatments, including this cream. Use may be contraindicated depending on individual history and the specifics of their condition.
The cream should be stored at room temperature away from direct sunlight and moisture. Keep the tube tightly closed when not in use, and keep out of reach of children and pets. Consult the product label or your pharmacist for any specific storage instructions.
If you miss a dose, apply the cream as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
Be sure to inform your healthcare provider of any allergies you may have. If you know you are allergic to either estriol or testosterone, or any of the other ingredients in the cream, you should not use it. Your healthcare provider can discuss alternative treatments with you.
It is recommended you discuss this with your healthcare provider. They might suggest waiting a certain amount of time after application before engaging in sexual activity to ensure the medication has been fully absorbed and to prevent transference of the medication to your partner.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Insert/apply intravaginally
