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The Hyoscyamine Sulfate 0.112 mg Rectal Suppository is a solid dosage form designed for insertion into the rectum. Upon administration, the suppository dissolves or melts, facilitating the release of hyoscyamine sulfate for local and systemic absorption. This medication is commonly used in the treatment of various gastrointestinal disorders, including irritable bowel syndrome, spastic colon, and colic. It also provides symptomatic relief from the hypermotility associated with diverticulitis and diverticulosis. Its anticholinergic properties help in reducing smooth muscle spasms and secretions in the digestive system.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Hyoscyamine Sulfate 0.112 mg Rectal Suppository is a solid dosage form designed for insertion into the rectum, where it dissolves or melts to release the active medication, hyoscyamine sulfate. This compound is an anticholinergic agent, which means it works by blocking the action of acetylcholine, a neurotransmitter that can cause muscle spasms and fluid secretions. By inhibiting acetylcholine, hyoscyamine sulfate helps to reduce muscle spasms in the gastrointestinal tract and other organs, making it useful in the treatment of various conditions.
It is also used to control the muscle spasms associated with disorders of the bladder, stomach, and intestines. Additionally, hyoscyamine can be prescribed for the symptomatic relief of peptic ulcer disease, as it reduces stomach acid secretion and gastrointestinal motility. In some cases, it may be used to alleviate the symptoms of Parkinson's disease and to control the excessive salivation associated with certain medical conditions.
The rectal suppository form of hyoscyamine sulfate offers certain advantages, such as bypassing the digestive system, which can be particularly beneficial for patients who are unable to take oral medications or for those who require rapid symptom relief. The 0.112 mg dosage provides a precise amount of medication, allowing for consistent dosing and minimizing the risk of side effects associated with systemic absorption.
Patients and prescribers should be aware that hyoscyamine sulfate can cause anticholinergic side effects, such as dry mouth, blurred vision, constipation, and urinary retention. It is important to use this medication under the guidance of a healthcare professional, who can monitor for these effects and adjust the treatment as necessary. Additionally, hyoscyamine sulfate may interact with other medications, so a thorough medication review is essential before starting treatment.
For those considering the use of Hyoscyamine Sulfate 0.112 mg Rectal Suppository, or for more detailed information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is available to answer any questions and provide the necessary support for both patients and prescribers to ensure appropriate treatment.
Hyoscyamine sulfate is an anticholinergic medication that works by blocking the action of acetylcholine, a neurotransmitter that mediates various functions in the body. This action helps to reduce muscle spasms in the gastrointestinal tract and bladder, as well as to decrease the secretions from certain organs. Hyoscyamine sulfate is commonly used to treat a variety of conditions, including irritable bowel syndrome, spastic bladder, peptic ulcer disease, and others that involve hypermotility or hypersecretory states.
When considering the use of hyoscyamine sulfate rectal suppositories, it is important to be aware of potential drug interactions that may affect the efficacy of the medication or increase the risk of adverse effects. Anticholinergic drugs like hyoscyamine can interact with a variety of other medications, including but not limited to antihistamines, antipsychotics, benzodiazepines, MAO inhibitors, tricyclic antidepressants, and other anticholinergics. These interactions can lead to increased anticholinergic effects, such as dry mouth, urinary retention, constipation, confusion, and blurred vision.
Additionally, the absorption of hyoscyamine sulfate may be affected by the concomitant use of antacids or other gastrointestinal medications. These can alter the gastric pH or motility, potentially affecting the release and absorption of the medication from the rectal suppository. It is also important to consider the potential for additive effects when used with other medications that have anticholinergic properties or that can cause drowsiness, such as opioid pain relievers, muscle relaxants, and sleep aids.
Patients with certain medical conditions should use hyoscyamine sulfate with caution, as the anticholinergic effects can exacerbate issues such as glaucoma, obstructive uropathy, obstructive diseases of the gastrointestinal tract, and myasthenia gravis. It is also important to avoid alcohol while using this medication, as it can increase drowsiness and further reduce the motility of the gastrointestinal tract.
It is crucial for patients and prescribers to review all current medications, including over-the-counter drugs and herbal supplements, to identify any potential interactions before starting treatment with hyoscyamine sulfate rectal suppositories. Monitoring for side effects and adjusting the dose accordingly is important to ensure the safe and appropriate use of this medication. If you have any questions or concerns regarding the use of hyoscyamine sulfate or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.
Hyoscyamine sulfate is an anticholinergic medication, which means it works by blocking the action of acetylcholine, a neurotransmitter that mediates various functions in the body. Acetylcholine is involved in transmitting nerve impulses responsible for muscle contractions, including those in the gastrointestinal tract, bladder, and other organs. By inhibiting the action of acetylcholine, hyoscyamine sulfate reduces muscle spasms and the production of bodily secretions such as saliva, sweat, and stomach acid.
When formulated as a 0.112 mg rectal suppository, hyoscyamine sulfate is designed to be inserted into the rectum where it dissolves or melts. This bypasses the digestive system, which can be beneficial for patients with gastrointestinal issues or those who cannot take oral medications.
The hyoscyamine sulfate rectal suppository is used to treat various disease states that involve muscle spasms and hypermotility of the gastrointestinal tract. These conditions include irritable bowel syndrome (IBS), colic, diverticulitis, and bladder spasms. It is also used to control the symptoms of Parkinson's disease and to reduce the side effects of certain medications that cause extrapyramidal reactions. Additionally, it can be used preoperatively to reduce salivary, tracheobronchial, and pharyngeal secretions.
By delivering the medication directly to the systemic circulation through the rectal mucosa, the suppository form of hyoscyamine sulfate ensures a more consistent and predictable response, which is particularly important for conditions that require rapid relief from symptoms. The use of a suppository can also be advantageous for patients experiencing nausea and vomiting, as it avoids the potential for the medication to be expelled before it can be absorbed.
It is important for both patients and prescribers to understand that while hyoscyamine sulfate can provide significant relief from symptoms, it may also cause side effects such as dry mouth, blurred vision, dizziness, and urinary retention due to its anticholinergic properties. Patients should be monitored for these effects, and the medication should be used with caution in individuals with certain medical conditions, such as glaucoma, enlarged prostate, or heart problems.
If you have any questions about the use of hyoscyamine sulfate rectal suppositories or would like more information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and appropriate use of this medication.
Hyoscyamine Sulfate 0.112 mg Rectal Suppository is a solid dosage form containing the medication hyoscyamine sulfate, which is intended to be inserted into the rectum. Upon insertion, the suppository dissolves or melts, releasing the medication for local or systemic absorption to alleviate various symptoms.
Once the suppository is inserted into the rectum, it begins to dissolve or melt due to body heat. The active ingredient, hyoscyamine sulfate, is then released and absorbed through the lining of the rectum into the bloodstream, to exert its effects on the body.
Hyoscyamine is commonly used to treat a variety of conditions that involve the digestive tract, such as irritable bowel syndrome, muscle spasms and cramps in the stomach and intestines, and ulcers. It can also be used for certain heart conditions, to control symptoms such as excessive salivation, or for bladder spasms.
The frequency of use for Hyoscyamine Sulfate 0.112 mg Rectal Suppositories should be as prescribed by your healthcare provider. It's important to follow their instructions carefully to ensure the best results from the medication.
For best results, lie on your side with your lower leg straightened out and your upper leg bent forward toward your stomach. Gently insert the suppository into the rectum with your finger, pointed end first, pushing it about 1 inch in for adults or less for children. Remain lying down for a few minutes to allow the suppository to melt and start to absorb.
Consult your healthcare provider before using Hyoscyamine Sulfate 0.112 mg Rectal Suppositories if you are pregnant or breastfeeding. They will be able to determine if the benefits outweigh any potential risks to you or your baby.
If you miss a dose of the Hyoscyamine Suppository, insert it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not insert two suppositories at one time to make up for a missed dose.
Hyoscyamine Sulfate may cause dizziness or drowsiness in some individuals. It's important to know how you react to the medication before driving or operating machinery. If you experience these side effects, it's best to avoid these activities.
Potential side effects may include dry mouth, blurred vision, dizziness, drowsiness, and constipation. If you experience any severe or persisting symptoms, or signs of an allergic reaction, seek immediate medical attention.
Store the suppositories in a cool, dry place away from light and moisture. Keep them out of reach of children and pets. Do not store in the bathroom or freezer, and avoid exposing the medication to high temperatures which can cause it to melt prematurely.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Insert 1 unwrapped suppository
