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Ibuprofen 20% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Ibuprofen

The Ibuprofen 20% Topical Gel is a semisolid formulation designed for targeted delivery of ibuprofen through the skin. This gel is dispensed from a convenient pump mechanism, ensuring easy and precise application. The consistency of the gel allows for smooth spreadability and rapid absorption of the active ingredient to the desired area. This formulation is primarily used to treat localized pain, inflammation, and swelling associated with conditions such as arthritis, tendonitis, and bursitis. It may also be beneficial in managing soft tissue injuries like sprains and strains, providing pain relief directly at the site of discomfort.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Ibuprofen
Topical Gel
65aee759d82cfd386a931969
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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The Ibuprofen 20% Topical Gel is a specialized semisolid formulation designed to deliver a high concentration of ibuprofen directly to the site of pain or inflammation. This gel is dispensed through a pump mechanism, which ensures that patients can apply a consistent and precise dose of medication to the affected area. The gel base allows for the ibuprofen to be absorbed through the skin, providing localized relief without the systemic side effects often associated with oral administration of nonsteroidal anti-inflammatory drugs (NSAIDs).

Ibuprofen, the active ingredient in this formulation, is a well-known NSAID that works by inhibiting the production of prostaglandins, chemicals in the body responsible for pain, fever, and inflammation. By applying the gel topically, ibuprofen can exert its effects directly at the site of musculoskeletal injuries, such as sprains, strains, and sports injuries, as well as conditions like arthritis. This targeted approach not only maximizes the therapeutic effects but also minimizes systemic absorption, reducing the risk of gastrointestinal irritation or cardiovascular effects that can be associated with oral NSAIDs.

Patients should be advised to apply the gel as directed by their healthcare provider, typically to clean, intact skin over the affected area. It is important to avoid contact with eyes, mucous membranes, and open wounds. The hands should be washed after application unless they are the site being treated. Prescribers should consider the patient's overall medication profile to avoid potential drug interactions and counsel patients on the signs of potential adverse effects, such as skin rash or hypersensitivity reactions.

For prescribers considering this formulation for their patients, it is important to note that the 20% concentration of ibuprofen in this gel is intended for significant anti-inflammatory and analgesic effects. This formulation may be particularly beneficial for patients who require localized pain management or those who are unable to tolerate oral NSAIDs. As with any medication, monitoring for efficacy and safety is recommended.

If you have any questions regarding the Ibuprofen 20% Topical Gel or its appropriate use, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is committed to providing comprehensive support and guidance to ensure the best possible outcomes for your patients.

Drug Interactions

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Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. When applied topically as a 20% gel, ibuprofen is used for the relief of pain and inflammation associated with conditions like arthritis, muscle sprains, strains, and other musculoskeletal injuries. While the systemic absorption of topical ibuprofen is lower than that of oral ibuprofen, there are still potential drug interactions that should be considered.

Patients using other NSAIDs, including aspirin or other over-the-counter pain relievers, should be cautious as the combined use may increase the risk of ulcers, bleeding, or kidney damage. Topical ibuprofen should be used with caution in patients taking anticoagulant medications (such as warfarin) or antiplatelet drugs (like clopidogrel), as there may be an increased risk of bleeding. Although the risk is lower with topical administration compared to systemic, it is not absent.

Concomitant use of ibuprofen with corticosteroids can also increase the risk of gastrointestinal side effects. Patients should be advised to avoid using other topical products on the same area where the ibuprofen gel is applied, as this may alter the absorption or increase the risk of adverse effects. Additionally, care should be taken when using the gel alongside selective serotonin reuptake inhibitors (SSRIs), as this may lead to an increased risk of gastrointestinal bleeding.

Patients with a history of heart disease should consult their healthcare provider before using ibuprofen gel, as NSAIDs can lead to an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke. This risk may be higher with systemic administration, but caution is still advised with topical use. Similarly, patients with renal impairment should use ibuprofen with caution, as NSAIDs can exacerbate renal dysfunction.

It is important to note that while the risk of systemic side effects is lower with topical application, patients should still be aware of the signs and symptoms of systemic side effects, such as gastrointestinal discomfort, renal issues, or allergic reactions. If any unusual symptoms occur, patients should discontinue use and seek medical advice.

Patients should also be advised to avoid applying the gel to broken or damaged skin, as this may increase systemic absorption and the potential for adverse effects. Sun exposure of the treated area should be minimized due to the potential for photosensitivity reactions.

For any questions or concerns regarding the use of ibuprofen 20% topical gel and potential drug interactions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and appropriate use of this medication.

How Does it Work

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The Ibuprofen 20% Topical Gel is a specially designed medication that delivers the anti-inflammatory and analgesic effects of ibuprofen directly to the site of pain or inflammation through the skin. Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), works by inhibiting the production of prostaglandins, which are substances in the body responsible for pain, fever, and inflammation. When applied topically, the ibuprofen in the gel form penetrates the skin to reach the underlying tissues where it reduces the synthesis of these prostaglandins, thereby alleviating pain and reducing swelling and inflammation.

The gel is formulated to ensure that the ibuprofen is solubilized and evenly distributed throughout the semisolid base, allowing for consistent delivery of the active ingredient with each application. The 20% concentration is specifically chosen to provide a high enough dose of ibuprofen to the affected area without the need for systemic administration, which can lead to unwanted side effects. The gel base is designed to be non-greasy and to absorb quickly into the skin, providing relief without leaving a residue.

The pump mechanism of the Ibuprofen 20% Topical Gel container is engineered to dispense a measured dose of the medication, ensuring that patients apply a consistent and accurate amount of the product each time. The pump also minimizes contamination of the product, as it prevents direct contact with the contents of the container.

This formulation is particularly useful for treating localized musculoskeletal conditions such as arthritis, tendonitis, bursitis, and other types of pain or inflammation. By applying the gel directly to the affected area, patients can experience targeted relief without the systemic side effects that can occur with oral NSAID administration, such as gastrointestinal irritation or cardiovascular risks. It is important to note that while the topical application of ibuprofen can provide significant relief, it should be used as directed by a healthcare professional and is not intended for the treatment of severe or systemic inflammatory conditions.

If you have any questions about the Ibuprofen 20% Topical Gel or its use in treating specific disease states, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to effectively manage pain and inflammation with this specialized formulation.

Frequently Asked Questions

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What is Ibuprofen 20% Topical Gel used for?

Ibuprofen 20% Topical Gel is used for targeted topical relief of mild to moderate pain, such as muscle aches, joint pain, and arthritis-related discomfort. It can also help reduce inflammation in the affected area.

How do I apply Ibuprofen 20% Topical Gel?

To apply the gel, press the pump to dispense a small amount onto your fingers and gently rub it into the skin over the affected area. Ensure that the area is clean and dry before application.

How often can I use Ibuprofen 20% Topical Gel?

Use this medication according to your healthcare provider's instructions. Generally, it can be applied up to four times a day, but you should not exceed the recommended dose without consulting a doctor.

Does Ibuprofen 20% Topical Gel have any side effects?

As with any medication, this gel may cause side effects. Common side effects include mild skin irritation at the application site. If you experience any severe side effects, such as increased pain, redness, swelling, or blistering of the skin, stop using the product and seek medical attention immediately.

Can I use Ibuprofen 20% Topical Gel with other medications?

While topical gels generally have fewer interactions with other medications, always inform your healthcare provider about all the medications you are taking to avoid potential interactions, especially if you are using other topical products or taking oral NSAIDs.

Should I cover the area after applying the gel?

It is not necessary to cover the area unless directed by a healthcare professional. Let the gel dry completely before covering with clothing to prevent the product from transferring to fabric.

Can I use Ibuprofen 20% Topical Gel if I am pregnant or breastfeeding?

Consult your healthcare provider before using this medication if you are pregnant or breastfeeding. They can provide advice on whether it is safe for you and your baby.

Is it safe to apply Ibuprofen 20% Topical Gel on broken skin or open wounds?

No, avoid applying the gel on broken skin, cuts, or open wounds. It is designed for application on intact skin only.

Can children use Ibuprofen 20% Topical Gel?

Always consult a pediatrician before using this medication for children. The safety and efficacy of topical ibuprofen gel in children have not been established without professional advice.

How should I store Ibuprofen 20% Topical Gel?

Store the gel at room temperature away from heat and moisture. Keep the container tightly closed when not in use, and make sure to keep it out of reach of children and pets.

What should I do if I miss a dose of Ibuprofen 20% Topical Gel?

If you miss a dose, apply it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Ibuprofen 20% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Three times daily