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The Isosorbide Mononitrate 12 mg/ml Oral Liquid is a specially compounded medication designed for oral use. This liquid formulation ensures precise dosing and ease of administration for patients who may have difficulty swallowing tablets or capsules, such as those in pediatric and geriatric populations. Isosorbide Mononitrate is primarily used in the treatment of angina pectoris due to coronary artery disease. By dilating blood vessels, it helps to reduce the frequency and severity of angina attacks. This oral liquid form is particularly beneficial for patients requiring tailored dosing or those with limitations that preclude the use of solid oral dosage forms.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Isosorbide Mononitrate 12 mg/ml Oral Liquid is a specially compounded medication designed for oral use, providing a precise 12 mg dose of Isosorbide Mononitrate per milliliter of liquid. This formulation is particularly beneficial for patients who have difficulty swallowing tablets or capsules, such as those in pediatric or geriatric populations, or for individuals with dysphagia or other conditions affecting the ability to swallow solid forms of medication. The liquid form allows for flexible dosing, which can be easily adjusted according to the specific needs of the patient.
Isosorbide Mononitrate is a nitrate-class drug that is commonly used to prevent angina pectoris (chest pain) associated with coronary artery disease. It works by relaxing and widening blood vessels, which allows blood to flow more easily, reducing the heart's workload and the oxygen demand of the heart muscle. This action helps to prevent the onset of angina attacks. It is important to note that Isosorbide Mononitrate is used for the prevention of angina attacks rather than for immediate relief of angina pain.
Patients and prescribers should be aware that the use of Isosorbide Mononitrate requires careful dosing and monitoring to ensure efficacy and minimize side effects, which may include headaches, dizziness, or lightheadedness due to its vasodilatory effects. It is also important to consider potential drug interactions, particularly with medications for erectile dysfunction or pulmonary hypertension, as these can lead to serious hypotension when combined with nitrates.
As compounding pharmacists at Bayview Pharmacy, we ensure that each batch of Isosorbide Mononitrate 12 mg/ml Oral Liquid is prepared to the highest standards of quality and consistency. We provide this custom medication in a form that is not readily available commercially, offering a tailored solution for our patients' unique needs. We are available to answer any questions and provide guidance to both patients and prescribers considering this formulation for the management of angina pectoris. For further information or to discuss specific requirements, please do not hesitate to reach out to us.
Isosorbide mononitrate is a nitrate-class drug commonly used to prevent angina pectoris (chest pain) associated with coronary artery disease. The 12 mg/ml oral liquid formulation of isosorbide mononitrate provides a convenient alternative for patients who have difficulty swallowing tablets or capsules, including pediatric and geriatric populations. However, it is important to be aware of potential drug interactions when taking this medication.
Isosorbide mononitrate can interact with other medications that affect blood pressure. Concurrent use with antihypertensive agents, such as beta-blockers, calcium channel blockers, and ACE inhibitors, may enhance the hypotensive effects of isosorbide mononitrate, potentially leading to symptomatic hypotension. Careful monitoring of blood pressure is advised when these drugs are used together. Additionally, patients taking diuretics should be monitored for signs of hypovolemia, which can exacerbate the blood pressure-lowering effects of isosorbide mononitrate.
Phosphodiesterase inhibitors (PDE5 inhibitors), such as sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra), used for erectile dysfunction, can cause severe hypotension when taken in combination with isosorbide mononitrate. This interaction is due to the additive vasodilatory effects of both drug classes. Patients should be advised not to take PDE5 inhibitors concurrently with isosorbide mononitrate or within 24 hours of its use.
Alcohol may also potentiate the vasodilatory and hypotensive effects of isosorbide mononitrate. Patients should be counseled to limit alcohol consumption while taking this medication to avoid episodes of dizziness or fainting. Additionally, the use of other central nervous system depressants, such as benzodiazepines or opioids, may enhance the sedative effects and further lower blood pressure, which requires caution and close monitoring.
Riociguat, a soluble guanylate cyclase stimulator, should not be used in combination with isosorbide mononitrate due to the risk of hypotension. The concomitant use of these medications is contraindicated.
Patients should also be aware that certain over-the-counter medications and herbal supplements can interact with isosorbide mononitrate. For example, products containing ephedra or yohimbine may counteract the therapeutic effects of isosorbide mononitrate and should be avoided.
It is crucial for patients to inform their healthcare providers of all medications they are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, to ensure the safe use of isosorbide mononitrate oral liquid. If you have any questions or concerns regarding potential drug interactions with isosorbide mononitrate, please reach out to us at Bayview Pharmacy for further assistance.
Isosorbide Mononitrate is an active pharmaceutical ingredient that belongs to a class of medications known as nitrates. Its primary mechanism of action involves the relaxation and widening of blood vessels, which is achieved through the conversion of isosorbide mononitrate to nitric oxide (NO) in the body. Nitric oxide is a potent vasodilator, meaning it helps to dilate or expand the blood vessels. This dilation reduces the workload on the heart by decreasing the resistance the heart must overcome to pump blood through the vessels, thereby lowering blood pressure and improving blood flow to the heart muscle itself.
The 12 mg/ml oral liquid formulation of Isosorbide Mononitrate provides a specific concentration that allows for precise dosing tailored to the needs of the patient. This liquid form is particularly beneficial for patients who have difficulty swallowing tablets or capsules, such as those with dysphagia, or for those who require a dosage that is not available in a standard pill form. The liquid formulation ensures that the medication can be administered easily and absorbed quickly into the bloodstream for a rapid onset of action.
In terms of disease states, Isosorbide Mononitrate is primarily used in the treatment of angina pectoris, which is chest pain or discomfort due to coronary artery disease. Angina occurs when the heart muscle doesn't receive enough oxygen-rich blood. By dilating the blood vessels, Isosorbide Mononitrate helps to increase the supply of blood and oxygen to the heart, thereby relieving angina symptoms. Additionally, it can be used in the management of chronic heart failure and may be prescribed for other conditions as determined by a healthcare provider.
It is important for patients and prescribers to understand that while Isosorbide Mononitrate can help control angina, it does not cure coronary artery disease or prevent heart attacks. Patients should follow the dosing instructions carefully and use the medication as part of a comprehensive treatment plan that may include lifestyle changes, other medications, and medical procedures. As with any medication, there may be potential side effects, and patients should be monitored for any adverse reactions.
If you have any questions about the Isosorbide Mononitrate 12 mg/ml Oral Liquid formulation or its use in treating specific disease states, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to ensure appropriate treatment for your patients or yourself.
Isosorbide Mononitrate 12 mg/ml Oral Liquid is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). This medication belongs to a class of drugs known as nitrates, and it works by dilating blood vessels, making it easier for the heart to pump blood.
Take Isosorbide Mononitrate Oral Liquid as prescribed by your physician. It is usually recommended to be taken once daily, with the dose carefully measured using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
If you miss a dose of Isosorbide Mononitrate Oral Liquid, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Isosorbide Mononitrate Oral Liquid can be taken with or without food. However, it is important to take it the same way each day because food can affect the way your body absorbs the medication.
Yes, like all medications, Isosorbide Mononitrate Oral Liquid may cause side effects. Common side effects may include headache, dizziness, lightheadedness, flushing, or nausea. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.
Alcohol can increase certain side effects of Isosorbide Mononitrate, such as dizziness and lightheadedness. It’s advisable to limit alcoholic beverages. Also, be cautious when standing or sitting up from a lying position to reduce the risk of dizziness and lightheadedness.
If you experience severe side effects or symptoms of an allergic reaction such as rash, itching/swelling, severe dizziness, or trouble breathing, seek immediate medical attention.
Store Isosorbide Mononitrate Oral Liquid at room temperature away from light and moisture. Do not store in the bathroom. Keep it out of reach of children and pets.
The safety and effectiveness of Isosorbide Mononitrate Oral Liquid in pediatric patients have not been established. It is important to consult a healthcare professional before administering this medication to children.
Patients who are allergic to isosorbide mononitrate or any other nitrates should not take this medication. Additionally, those with a history of certain medical conditions, such as low blood pressure or severe anemia, should consult with a healthcare provider before using Isosorbide Mononitrate Oral Liquid. Always provide your full medical history to your physician before starting any new medication.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Take orally
