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Liothyronine Sodium 5 mcg/0.1mL Topical Cream

FDA-approved generic
Dose form
Topical Cream
Active ingredients
Liothyronine Sodium

Liothyronine Sodium 5 mcg/0.1mL Topical Cream is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. This formulation is used to treat conditions such as hypothyroidism and myxedema, providing localized treatment or absorption of active ingredients to help manage these disease states effectively.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Liothyronine Sodium
Topical Cream

Formula Information

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Drug Interactions

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Liothyronine Sodium 5 mcg/0.1mL Topical Cream is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin for localized treatment or absorption of active ingredients. This formulation is primarily used to manage conditions related to thyroid hormone deficiencies, such as hypothyroidism, where it helps to supplement the body's natural thyroid hormone levels. By applying the cream topically, it allows for localized treatment, potentially minimizing systemic side effects and providing a targeted approach to therapy.

When considering the use of Liothyronine Sodium in a topical cream formulation, it is crucial to be aware of potential drug interactions that could affect the efficacy and safety of the treatment. Although topical application may reduce the likelihood of systemic interactions compared to oral administration, some interactions may still occur, especially if the medication is absorbed into the bloodstream.

Patients using this formulation should be cautious if they are concurrently taking other medications that affect thyroid hormone levels or metabolism. For instance, drugs such as amiodarone, which can alter thyroid hormone metabolism, may impact the effectiveness of Liothyronine Sodium. Similarly, medications like beta-blockers, which can mask symptoms of hyperthyroidism, may complicate the monitoring of thyroid function and the assessment of treatment efficacy.

Additionally, certain medications that affect the absorption or metabolism of thyroid hormones, such as antacids containing aluminum or calcium, iron supplements, and certain cholesterol-lowering drugs like cholestyramine, may interfere with the absorption of Liothyronine Sodium if it enters systemic circulation. It is advisable to apply the cream at a different time from when these medications are taken orally to minimize potential interactions.

Patients should also be aware of the potential for interactions with anticoagulants such as warfarin. Thyroid hormones can enhance the effects of anticoagulants, increasing the risk of bleeding. Regular monitoring of blood coagulation parameters is recommended if these medications are used concurrently.

For prescribers, it is important to consider the patient's overall medication regimen and any existing medical conditions that may influence the use of Liothyronine Sodium Topical Cream. Regular monitoring of thyroid function tests is recommended to ensure therapeutic efficacy and to adjust the dosage as necessary. Additionally, prescribers should educate patients on the signs of thyroid hormone imbalance, such as changes in heart rate, weight, or mood, and advise them to report any unusual symptoms promptly.

If you have any questions or need further information regarding the use of Liothyronine Sodium 5 mcg/0.1mL Topical Cream, please reach out to us. Our team of compounding pharmacists at Bayview Pharmacy is here to assist you with any concerns or inquiries you may have.

How Does it Work

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Liothyronine Sodium 5 mcg/0.1mL Topical Cream is a specialized formulation designed to deliver the active thyroid hormone, liothyronine, directly through the skin. This semisolid preparation is dispensed using a pump mechanism, ensuring precise dosing and ease of application. The topical route of administration allows for localized treatment, which can be particularly beneficial for patients who require targeted therapy or have difficulty with oral medications.

Liothyronine, a synthetic form of the thyroid hormone triiodothyronine (T3), plays a crucial role in regulating metabolism, energy production, and overall cellular function. When applied topically, liothyronine sodium is absorbed through the skin and enters the bloodstream, where it can exert its physiological effects. This method of delivery can be advantageous for patients with conditions that affect the skin or localized areas, as it allows for direct application to the affected site, potentially reducing systemic side effects associated with oral administration.

The formulation of this topical cream is carefully designed to enhance the absorption of liothyronine through the skin. The cream base is composed of ingredients that facilitate the penetration of the active ingredient, ensuring that an adequate amount reaches the target tissues. The pump mechanism provides a controlled dose with each application, minimizing the risk of over- or under-dosing and promoting consistent therapeutic outcomes.

For patients with conditions such as hypothyroidism or other thyroid-related disorders, the use of liothyronine sodium in a topical form can offer a novel approach to management. By bypassing the gastrointestinal tract, this formulation may be particularly useful for individuals who experience gastrointestinal side effects from oral medications or have absorption issues. Additionally, the localized application can be tailored to specific areas, providing a more personalized treatment option.

Prescribers considering this formulation for their patients should evaluate the specific needs and conditions of each individual. The topical application of liothyronine sodium may be suitable for those who require a more targeted approach or have contraindications to oral therapy. It is important to monitor patients for therapeutic efficacy and any potential side effects, adjusting the treatment regimen as necessary to achieve optimal results.

If you have any questions or require further information about Liothyronine Sodium 5 mcg/0.1mL Topical Cream, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or concerns you may have regarding this formulation.

Other Uses

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Liothyronine Sodium 5 mcg/0.1mL Topical Cream, dispensed in a semisolid preparation with a pump mechanism, is primarily used for the treatment of hypothyroidism and related thyroid disorders. However, this formulation may have other potential uses that could be of interest to both patients and prescribers. One such use is in the management of certain dermatological conditions where thyroid hormone modulation might play a role. For instance, some studies suggest that thyroid hormones can influence skin health, potentially aiding in the treatment of conditions like psoriasis or eczema by modulating local inflammation and promoting skin repair. The topical application allows for localized treatment, minimizing systemic exposure and potential side effects associated with oral administration.

Additionally, there is emerging interest in the use of topical liothyronine for enhancing wound healing. Thyroid hormones are known to play a role in cellular metabolism and tissue regeneration, which could be beneficial in accelerating the healing process of chronic wounds or ulcers.

Another potential use of this formulation is in the field of cosmetic dermatology. Liothyronine may have a role in anti-aging treatments due to its ability to enhance cellular turnover and improve skin elasticity. By applying the hormone directly to the skin, it may help reduce the appearance of fine lines and wrinkles, offering a novel approach to skin rejuvenation therapies.

It is important for prescribers to consider the individual needs of their patients and the specific characteristics of the condition being treated when contemplating the use of Liothyronine Sodium 5 mcg/0.1mL Topical Cream for off-label purposes. Patients should be informed about the potential benefits and risks, and treatment should be closely monitored to ensure safety and efficacy. As always, if you have any questions or need further information, please reach out to us at Bayview Pharmacy.

Frequently Asked Questions

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What is Liothyronine Sodium 5 mcg/0.1mL Topical Cream used for?

This topical cream is used for localized treatment or absorption of Liothyronine Sodium, which is a form of thyroid hormone. It is typically used to manage conditions related to thyroid hormone deficiency.

How should I apply the Liothyronine Sodium topical cream?

The cream should be applied to clean, dry skin. Dispense the prescribed amount using the pump mechanism and gently rub it into the skin until fully absorbed.

How often should I use this topical cream?

Your healthcare provider will provide specific instructions on how often to use the cream, typically based on your individual needs and condition.

Can I use this cream on any part of my body?

It is important to follow your healthcare provider's instructions regarding the application sites. Some areas may be more suitable for absorption than others.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose.

Are there any side effects associated with this topical cream?

Some users may experience skin irritation at the application site. If you notice any severe reactions or unusual symptoms, contact your healthcare provider immediately.

Can I use this cream if I am pregnant or breastfeeding?

You should consult your healthcare provider before using this cream if you are pregnant or breastfeeding to ensure it is safe for you and your baby.

How should I store the Liothyronine Sodium topical cream?

Store the cream at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Can I use other topical medications while using this cream?

Before using other topical medications, consult your healthcare provider to avoid potential interactions or reduced effectiveness of the treatments.

What should I do if I experience an allergic reaction?

If you experience symptoms of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, seek medical attention immediately.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Liothyronine Sodium 5 mcg/0.1mL Topical Cream
Topical Cream
30 g
controlled

Apply topically to affected area(s)