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Melatonin 5 mg/g/Progesterone 5 mg/g Topical Cream

FDA-approved generic
Dose form
Topical Cream
Active ingredients
Melatonin
Progesterone

This Melatonin 5 mg/g/Progesterone 5 mg/g Topical Cream is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. It is formulated to provide localized treatment or absorption of active ingredients, specifically targeting conditions such as insomnia, hormonal imbalances, and menopausal symptoms. The combination of melatonin and progesterone in this topical cream aims to support sleep regulation and hormonal balance, offering a therapeutic option for individuals experiencing these disease states.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Get a one-page sheet with everything your doctor needs to prescribe this and send it to Bayview.

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Melatonin
Progesterone
Topical Cream
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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Melatonin 5 mg/g and Progesterone 5 mg/g Topical Cream is a compounded formulation designed for transdermal delivery of these hormones. The semisolid cream is dispensed through a convenient pump mechanism, allowing for precise dosing and controlled application to the skin for localized treatment or systemic absorption of the active ingredients.

Melatonin is a hormone naturally produced by the pineal gland, primarily responsible for regulating the sleep-wake cycle, also known as the circadian rhythm. When applied topically, melatonin may aid in adjusting sleep patterns by facilitating absorption through the skin, potentially benefiting individuals experiencing sleep disturbances or jet lag. Additionally, melatonin possesses antioxidant properties that may help protect skin cells from oxidative stress caused by environmental factors such as UV radiation.

Progesterone is a key hormone involved in the menstrual cycle, pregnancy, and embryogenesis. Topical application of progesterone cream is commonly used in hormone replacement therapy to alleviate symptoms associated with hormonal imbalances, such as those experienced during menopause or premenstrual syndrome (PMS). By administering progesterone transdermally, patients may achieve more consistent hormone levels while potentially reducing side effects associated with oral progesterone, like gastrointestinal discomfort.

The combination of melatonin and progesterone in this topical cream may offer synergistic benefits for individuals dealing with both sleep disturbances and hormonal imbalance symptoms. This formulation allows for simultaneous administration of both hormones, which may enhance patient compliance and overall therapeutic outcomes. It provides a personalized approach to therapy, catering to the unique needs of each patient under the guidance of their healthcare provider.

Patients interested in using this compounded topical cream should consult with their healthcare provider to determine its suitability for their specific health needs. Prescribers may consider this formulation for patients who require customized dosing regimens or who prefer transdermal delivery methods over oral medications. The controlled dosing mechanism ensures accurate delivery of the active ingredients, which is crucial for achieving the desired therapeutic effects.

If you have any questions or need further information about this formulation, please reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to assist both patients and healthcare providers with any inquiries or support needed regarding this medication.

Drug Interactions

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When using the Melatonin 5 mg/g/Progesterone 5 mg/g Topical Cream, it is important to consider potential drug interactions that may affect the efficacy and safety of the treatment. This formulation is designed for topical application, allowing for localized treatment or absorption of the active ingredients through the skin. However, systemic absorption can still occur, and interactions with other medications should be carefully monitored.

Melatonin, a hormone that regulates sleep-wake cycles, can interact with various medications. Patients taking anticoagulants or antiplatelet drugs, such as warfarin or aspirin, should be cautious, as melatonin may increase the risk of bleeding. Additionally, melatonin can interact with medications that affect the central nervous system, such as benzodiazepines, sedatives, and antidepressants, potentially enhancing their sedative effects. Patients using immunosuppressants should also be aware that melatonin might alter immune function, potentially affecting the efficacy of these drugs.

Progesterone, a hormone involved in the menstrual cycle and pregnancy, can interact with a range of medications. It may affect the metabolism of drugs processed by the liver, particularly those metabolized by the cytochrome P450 enzyme system. This can alter the plasma concentrations of medications such as certain anticonvulsants, antifungals, and antibiotics, potentially requiring dose adjustments. Progesterone may also interact with other hormone therapies, including estrogen, potentially affecting hormone balance and efficacy.

Patients using this topical cream should inform their healthcare provider of all medications they are currently taking, including over-the-counter drugs and supplements, to assess potential interactions. It is also important to consider any underlying health conditions that may be affected by changes in hormone levels or immune function. For prescribers, careful consideration of the patient's medication regimen and health status is essential to minimize the risk of adverse interactions and optimize treatment outcomes.

If you have any questions or concerns about potential drug interactions with the Melatonin 5 mg/g/Progesterone 5 mg/g Topical Cream, please reach out to us for further guidance and support.

How Does it Work

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The Melatonin 5 mg/g/Progesterone 5 mg/g Topical Cream is a specialized formulation designed to deliver active ingredients directly through the skin, utilizing a semisolid preparation dispensed via a pump mechanism. This method ensures a convenient and controlled application, allowing for precise dosing and targeted delivery of the active compounds to the desired area. The topical route of administration is particularly beneficial for localized treatment, minimizing systemic exposure and potential side effects associated with oral or systemic therapies.

Melatonin, a hormone primarily known for its role in regulating sleep-wake cycles, also possesses antioxidant and anti-inflammatory properties. When applied topically, melatonin can penetrate the skin barrier and exert its effects locally. It may help in reducing oxidative stress and inflammation in the skin, potentially benefiting conditions characterized by these underlying issues. Additionally, melatonin's ability to modulate immune responses can further contribute to its therapeutic effects in certain dermatological conditions.

Progesterone, a naturally occurring steroid hormone, plays a crucial role in the regulation of various physiological processes, including the menstrual cycle and pregnancy. In topical formulations, progesterone can be absorbed through the skin and exert its effects locally or systemically, depending on the site of application and the condition being treated. Topical progesterone is often used in hormone replacement therapy, particularly for alleviating symptoms associated with menopause, such as hot flashes and mood swings. It may also be beneficial in managing certain skin conditions by promoting skin elasticity and hydration, as well as modulating inflammatory responses.

The combination of melatonin and progesterone in this topical cream offers a synergistic approach to treatment, potentially enhancing the therapeutic outcomes for patients. The precise mechanism of action will depend on the specific condition being treated, as well as individual patient factors. The pump mechanism of the cream ensures that each application delivers a consistent dose of the active ingredients, promoting adherence to treatment regimens and optimizing therapeutic efficacy.

For both patients and prescribers, understanding the pharmacokinetics and pharmacodynamics of this formulation is essential for maximizing its benefits. Patients should be advised on the correct application technique and frequency to ensure optimal absorption and therapeutic effect. Prescribers should consider the patient's overall health status, concurrent medications, and specific treatment goals when recommending this formulation.

If you have any questions or require further information about the Melatonin 5 mg/g/Progesterone 5 mg/g Topical Cream, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you with any inquiries or concerns you may have.

Frequently Asked Questions

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What is Melatonin 5 mg/g/Progesterone 5 mg/g Topical Cream used for?

This topical cream is used for localized treatment or absorption of melatonin and progesterone through the skin. It may be used to support sleep regulation and hormonal balance.

How do I apply the Melatonin/Progesterone Topical Cream?

Apply the cream to clean, dry skin using the pump mechanism for a controlled dose. Gently massage the cream into the skin until fully absorbed.

Where should I apply the Melatonin/Progesterone Topical Cream?

The cream can be applied to areas of the skin where absorption is optimal, such as the inner arms, thighs, or abdomen. Follow your healthcare provider's instructions for specific application sites.

How often should I use the Melatonin/Progesterone Topical Cream?

Use the cream as directed by your healthcare provider. Typically, it may be applied once daily, but follow the specific instructions provided for your treatment plan.

Can I use the Melatonin/Progesterone Topical Cream with other medications?

Consult your healthcare provider before using this cream with other medications to avoid potential interactions. They can provide guidance based on your specific health needs.

Are there any side effects associated with the Melatonin/Progesterone Topical Cream?

Some users may experience skin irritation or allergic reactions. If you notice any adverse effects, discontinue use and consult your healthcare provider.

How should I store the Melatonin/Progesterone Topical Cream?

Store the cream at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Is a prescription required for the Melatonin/Progesterone Topical Cream?

Yes, a prescription is typically required for this compounded formulation. Consult your healthcare provider to determine if it is appropriate for you.

Can I use the Melatonin/Progesterone Topical Cream if I am pregnant or breastfeeding?

Consult your healthcare provider before using this cream if you are pregnant or breastfeeding, as they can provide guidance based on your individual health circumstances.

What should I do if I miss a dose of the Melatonin/Progesterone Topical Cream?

If you miss a dose, apply it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Melatonin 5 mg/g/Progesterone 5 mg/g Topical Cream
Topical Cream
30 g
controlled

Apply topically to affected area(s)

Once daily