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Methotrexate 0.01% Topical Cream

FDA-approved generic
Dose form
Topical Cream
Active ingredients
Methotrexate

Methotrexate 0.01% Topical Cream is a semisolid preparation, dispensed via a pump mechanism for easy and controlled application. It is designed for localized treatment of skin conditions such as psoriasis, eczema, lichen planus, seborrheic dermatitis, and acne rosacea, facilitating the absorption of active ingredients directly on the affected area.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Methotrexate
Topical Cream
6427079ea64324f907518df3

Formula Information

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Methotrexate 0.01% Topical Cream is a prescription medication, specifically a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. It is primarily used for the localized treatment or absorption of active ingredients in a variety of skin conditions, including psoriasis, eczema, and dermatitis. This medication functions by reducing inflammation and suppressing the immune system, providing relief from these skin conditions.

It is applied directly to the affected area of skin as per the instructions of your healthcare provider. However, it is crucial to adhere to your healthcare provider’s instructions for use, as improper use can lead to serious side effects. Some common side effects include skin irritation, redness, and dryness.

For patients using Methotrexate 0.01% Topical Cream, it is essential to use the medication as directed and to avoid contact with the eyes, mouth, and other mucous membranes. It is also advised to avoid sun exposure and to wear protective clothing when outdoors to prevent any adverse reactions.

For healthcare providers prescribing Methotrexate 0.01% Topical Cream, it is important to monitor patients for signs of side effects and to adjust the dosage as needed.

If you have any questions or concerns about Methotrexate 0.01% Topical Cream, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide the necessary guidance and support.

Drug Interactions

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Methotrexate 0.01% Topical Cream is a semisolid preparation that is dispensed via a pump mechanism, designed for easy and controlled application on the skin. This formulation is primarily used for the localized treatment of various inflammatory skin conditions such as psoriasis and atopic dermatitis. The active ingredient, Methotrexate, works by inhibiting the production of certain inflammatory mediators, including prostaglandins and leukotrienes, which play a significant role in the inflammatory response.

In addition to its anti-inflammatory properties, Methotrexate also exhibits immunomodulatory effects that can help reduce inflammation and improve overall skin health. However, it is important to note that Methotrexate should be used with caution in patients with renal or hepatic impairment, as it can lead to increased levels of methotrexate in the blood. Similarly, patients with a history of alcohol abuse should exercise caution, as the use of Methotrexate can increase the risk of liver damage.

Patients using Methotrexate 0.01% Topical Cream should be closely monitored for signs of liver toxicity, such as jaundice, dark urine, or abdominal pain. Additionally, signs of skin irritation, such as redness, itching, or burning, should also be closely observed. If any of these side effects occur, it is recommended that the patient discontinue the use of the medication and immediately contact their healthcare provider.

If you have any questions or concerns regarding the use of Methotrexate 0.01% Topical Cream, please do not hesitate to reach out to your healthcare provider for further information and guidance.

How Does it Work

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Methotrexate 0.01% Topical Cream is a specialized medication designed to treat a range of skin conditions, including psoriasis, eczema, and atopic dermatitis. This cream works by reducing inflammation and suppressing the immune system, thereby alleviating the symptoms associated with these skin conditions. It is a semisolid preparation dispensed in a pump mechanism, which allows for convenient and controlled application directly onto the affected skin area.

Typically, the cream is applied once or twice daily, or as directed by your healthcare provider. It is crucial to adhere to the instructions provided by your doctor or pharmacist when using this medication to ensure its effectiveness and to minimize potential side effects.

While Methotrexate 0.01% Topical Cream is generally well tolerated, some individuals may experience side effects such as skin irritation, burning, or stinging. If you experience any of these side effects, it is important to seek advice from your doctor or pharmacist. Additionally, care should be taken to avoid contact with the eyes, mouth, and other mucous membranes when applying the cream.

Methotrexate 0.01% Topical Cream is a potent treatment for many skin conditions. However, its effectiveness is dependent on correct usage. If you have any questions or concerns about how to use this medication, do not hesitate to contact your healthcare provider for guidance.

Other Uses

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Methotrexate 0.01% Topical Cream is a versatile treatment option for a wide range of skin conditions and diseases. It is commonly used to manage conditions such as atopic dermatitis, contact dermatitis, and alopecia areata.

Aside from these, Methotrexate 0.01% Topical Cream is also utilized in the treatment of certain types of cancer, including breast cancer, non-Hodgkin's lymphoma, and leukemia. It has shown efficacy in managing eye diseases such as uveitis and macular degeneration. This topical cream is also used in the treatment of autoimmune diseases like systemic lupus erythematosus and Sjogren's syndrome.

Furthermore, Methotrexate 0.01% Topical Cream is used to treat skin diseases such as pemphigus vulgaris and pemphigoid. This cream is also used in the management of inflammatory diseases like Crohn's disease and ulcerative colitis.

Lastly, Methotrexate 0.01% Topical Cream is used in the treatment of certain types of skin cancers, such as basal cell carcinoma and squamous cell carcinoma. If you have any questions about the use of Methotrexate 0.01% Topical Cream for any of these conditions, please do not hesitate to reach out.

Frequently Asked Questions

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What is Methotrexate 0.01% Topical Cream?

Methotrexate 0.01% Topical Cream is a semisolid preparation of the medication Methotrexate. It is designed for direct application on the skin for localized treatment or absorption of the active ingredient, Methotrexate.

How is Methotrexate 0.01% Topical Cream dispensed?

This cream is dispensed in a pump mechanism, which allows for convenient and controlled application on the skin.

What is the purpose of the pump mechanism in the Methotrexate 0.01% Topical Cream?

The pump mechanism is designed to provide a controlled amount of the cream for application, ensuring the correct dosage is used each time.

What is the active ingredient in Methotrexate 0.01% Topical Cream?

The active ingredient in this cream is Methotrexate, a medication often used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis that has not responded to other treatments.

How should Methotrexate 0.01% Topical Cream be stored?

It should be stored at room temperature, away from heat and direct light. Do not freeze. Keep out of the reach of children.

What are the potential side effects of Methotrexate 0.01% Topical Cream?

Side effects can include redness, itching, or irritation at the application site. If these symptoms persist or worsen, contact your healthcare provider immediately.

How often should I apply Methotrexate 0.01% Topical Cream?

The frequency of application should be determined by your healthcare provider, based on your specific condition and response to treatment.

Can Methotrexate 0.01% Topical Cream be used with other medications?

Before starting any new medication, it is important to discuss with your healthcare provider. Some medications may interact with Methotrexate, affecting its effectiveness or causing side effects.

What should I do if I miss a dose of Methotrexate 0.01% Topical Cream?

If you miss a dose, apply it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Do not double the dose to catch up.

Is Methotrexate 0.01% Topical Cream safe for pregnant or breastfeeding women?

Methotrexate is not recommended for use during pregnancy or while breastfeeding. It may harm an unborn baby or a nursing infant. Consult your healthcare provider for more information.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Methotrexate 0.01% Topical Cream
Topical Cream
30 g
controlled

Apply topically to affected area(s)