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Formulas

Paromomycin 150 mg/5 mL Oral Liquid

FDA-approved generic
Dose form
Oral Liquid
Active ingredients
Paromomycin Sulfate

Our Paromomycin 150 mg/5 mL Oral Liquid is a specially compounded medication designed for oral use. This formulation offers a precise and accessible means of medication delivery, particularly beneficial for patients who experience difficulty swallowing pills, such as children and the elderly. The liquid form ensures accurate dosing and ease of administration.

This oral liquid formulation is commonly used to treat intestinal amebiasis, which is an infection of the intestines caused by the parasite Entamoeba histolytica. Additionally, it is used in the management of hepatic coma, a complication of liver disease, where it helps reduce the production of ammonia-forming bacteria in the intestinal tract.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Paromomycin Sulfate
Oral Liquid
65ce4a5e98498816e03cc254
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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Paromomycin 150 mg/5 mL Oral Liquid is a custom-prepared medication designed for ease of administration and precise dosing. This formulation is particularly beneficial for patients who have difficulty swallowing pills, such as children and the elderly, or for those who require a modified dosage that is not available in commercial tablet or capsule forms. The liquid formulation allows for flexible dosing, which can be adjusted according to the specific needs of the patient.

It works by binding to the bacterial ribosomal RNA, thereby inhibiting protein synthesis and ultimately leading to cell death. This medication is commonly used to treat intestinal amebiasis, which is an infection caused by the protozoan Entamoeba histolytica. Additionally, it is used in the management of hepatic coma as an adjunct therapy to reduce the ammonia-forming bacteria in the intestinal tract, and it can be used to treat certain parasitic infections, such as tapeworm.

For patients and prescribers considering the use of Paromomycin 150 mg/5 mL Oral Liquid, it is important to note that the dosing must be individualized based on the severity of the infection, the patient's renal function, and body weight. Monitoring of kidney function and hearing is recommended due to the potential nephrotoxic and ototoxic effects associated with aminoglycosides. As with all medications, there may be potential side effects, and it is crucial to balance the benefits of treatment against the risks. Patients should be counseled on the importance of completing the full course of therapy, even if symptoms improve, to prevent the development of resistance.

At Bayview Pharmacy, our team of compounding pharmacists is dedicated to providing high-quality, personalized medications to meet the unique needs of each patient. We ensure that our formulations are prepared with precision and in accordance with the highest standards of pharmaceutical care. If you have any questions about Paromomycin 150 mg/5 mL Oral Liquid or would like to discuss its suitability for your condition, please do not hesitate to reach out to us. We are here to support both patients and healthcare providers with expert advice and comprehensive medication solutions.

Drug Interactions

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Paromomycin is an aminoglycoside antibiotic that is used to treat a variety of parasitic and bacterial infections. It works by binding to bacterial ribosomal RNA, thereby inhibiting protein synthesis and leading to the death of the bacteria or parasite. This oral liquid formulation of paromomycin is particularly useful for patients who have difficulty swallowing pills, such as children and the elderly, or for those who require a precise dosage that can be easily adjusted.

When considering the use of paromomycin, it is important to be aware of potential drug interactions that may affect the efficacy of the treatment or cause adverse effects. Paromomycin should be used with caution in patients taking other nephrotoxic or ototoxic drugs, such as other aminoglycosides, cisplatin, and loop diuretics like furosemide, as the combination may increase the risk of kidney damage and hearing loss. Concurrent use with neuromuscular blocking agents, such as succinylcholine or tubocurarine, may enhance the neuromuscular blocking effects, which could lead to increased muscle weakness or respiratory depression.

Patients on anticoagulant therapy, such as warfarin, should be monitored closely as paromomycin may alter the intestinal flora, leading to a reduction in vitamin K production and an increased risk of bleeding. Additionally, the concurrent use of paromomycin with oral anti-diabetic medications or insulin may lead to alterations in blood glucose levels, necessitating adjustments in the dosing of the anti-diabetic drugs.

It is also important to consider that the absorption of paromomycin may be affected by the presence of other medications. For instance, the concurrent use of kaolin-pectin and other gastrointestinal motility agents may decrease the absorption of paromomycin from the gastrointestinal tract, potentially reducing its efficacy. Patients should be advised to take paromomycin at least 2 hours before or after using such agents.

Lastly, as paromomycin is primarily excreted by the kidneys, caution should be exercised when prescribing this medication to patients with impaired renal function. Dosage adjustments may be necessary to prevent accumulation of the drug and subsequent toxicity. Regular monitoring of renal function, as well as auditory and vestibular function, is recommended for patients on prolonged therapy or those receiving high doses.

It is essential for patients and prescribers to be aware of these potential interactions and to monitor for signs of toxicity or reduced efficacy when paromomycin is used in combination with other medications. If you have any questions or concerns regarding the use of paromomycin oral liquid formulation or its interactions with other drugs, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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Paromomycin is an aminoglycoside antibiotic that works by binding to the bacterial ribosomal RNA, specifically the 16S rRNA of the 30S subunit, inhibiting protein synthesis in susceptible bacteria. The 150 mg/5 mL oral liquid formulation of paromomycin is designed to provide a precise dosage in a form that is easier to swallow than solid dosage forms, which is particularly beneficial for patients who have difficulty swallowing pills, such as children and the elderly.

The liquid formulation ensures that the medication is readily absorbed and distributed in the body. Paromomycin is commonly used to treat intestinal amebiasis, which is an infection of the intestines caused by the parasite Entamoeba histolytica. It is also used in the management of hepatic coma, as it reduces the ammonia-forming bacteria in the intestinal tract, thereby lowering blood ammonia levels. Additionally, paromomycin is used off-label for the treatment of certain parasitic infections, such as leishmaniasis and tapeworm infections.

For patients and prescribers considering this formulation, it is important to note that the efficacy of paromomycin depends on the correct dosage and adherence to the prescribed treatment regimen. The liquid form allows for flexible dosing, which can be adjusted according to the specific needs of the patient. It is also essential to consider potential side effects, drug interactions, and contraindications associated with paromomycin, as with any medication. Monitoring for signs of ototoxicity and nephrotoxicity is particularly important with aminoglycosides, including paromomycin.

If you have any questions about the paromomycin 150 mg/5 mL oral liquid formulation or its use in treating specific disease states, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to ensure appropriate treatment for your patients.

Frequently Asked Questions

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What is Paromomycin 150 mg/5 mL Oral Liquid used for?

Paromomycin 150 mg/5 mL Oral Liquid is an antibiotic medication used to treat certain parasitic infections in the body, including intestinal amebiasis. It works by stopping the growth of the parasite responsible for the infection.

How should Paromomycin Oral Liquid be taken?

This medication should be taken exactly as prescribed by your healthcare provider. The usual method involves measuring the prescribed dose with the provided dosing device and taking it by mouth, with or without food. Be sure to shake the bottle well before each use.

Can children take this oral liquid formulation of Paromomycin?

Yes, this specifically formulated liquid medication is suitable for children, but the dose will vary based on their weight and the severity of the infection. Always consult a healthcare provider for the appropriate dosage for a child.

Is Paromomycin Oral Liquid suitable for the elderly?

Yes, it is suitable for geriatric use. Elderly patients who have difficulty swallowing solid dosage forms may find this liquid version easier to ingest. However, they should be monitored closely by their healthcare provider, as dosing may need adjustments based on their renal function and overall health.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your usual dosing schedule. Do not double up to make up for the missed dose.

Can I mix the liquid with other liquids or food?

It's best to take the liquid medication as directed by your healthcare provider. In some cases, you may be advised that it is permissible to mix with certain liquids or foods to make the medicine more palatable, particularly for children. However, this should only be done if advised by a healthcare provider or pharmacist.

Are there any storage requirements for Paromomycin Oral Liquid?

Yes, you should store the medication at room temperature away from light and moisture, and keep it out of the reach of children and pets. Do not refrigerate or freeze the medication, and do not store it in the bathroom.

What are the potential side effects of Paromomycin Oral Liquid?

Some common side effects include nausea, vomiting, abdominal cramps, and diarrhea. If any of these effects persist or worsen, contact your healthcare provider immediately. Seek medical attention if you experience signs of an allergic reaction or a more serious adverse effect.

Can I drink alcohol while taking Paromomycin Oral Liquid?

Alcohol may interact with certain medications and can worsen side effects such as nausea or dizziness. It's best to avoid alcohol while taking this medication unless your healthcare provider advises otherwise.

Do I need a prescription to purchase Paromomycin 150 mg/5 mL Oral Liquid?

Yes, Paromomycin Oral Liquid is a medication that requires a prescription from a healthcare provider. Do not use this medicine without a prescription, and use only for the condition for which it was prescribed.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Paromomycin 150 mg/5 mL Oral Liquid
Oral Liquid
controlled

Take orally

Every 8 hours