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Primidone 25 mg/5 mL Oral Liquid

FDA-approved generic
Dose form
Oral Liquid
Active ingredients
Primidone

The Primidone 25 mg/5 mL Oral Liquid is a specially compounded medication designed for oral use, offering a precise and manageable method for administering the required dose of primidone. This liquid formulation is particularly beneficial for patients who experience difficulty swallowing tablets or capsules, such as children and the elderly. Primidone is an anticonvulsant drug commonly used to treat and manage epilepsy and seizures. By providing the medication in liquid form, it ensures that patients who are unable to take solid forms of medication can still receive their necessary treatment effectively and safely.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Primidone
Oral Liquid
65ce332e7c5f1bb9f6e5efc1
Service area

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Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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Primidone 25 mg/5 mL Oral Liquid is a specially crafted medication designed for oral use, providing a precise and manageable method for administering the prescribed dose of primidone. This liquid formulation is particularly beneficial for patients who experience difficulty swallowing tablets or capsules, such as children and the elderly, or those with dysphagia or other conditions affecting the ability to swallow solid forms of medication. The liquid form ensures that the medication can be ingested easily and safely, with the added ability to adjust doses as needed for individual patient requirements.

Primidone is an anticonvulsant medication primarily used in the treatment of seizure disorders, including epilepsy. It works by decreasing abnormal electrical activity in the brain, thereby reducing the frequency and severity of seizures. This medication may be used alone or in combination with other antiepileptic drugs to control various types of seizures.

For patients and prescribers considering the use of Primidone 25 mg/5 mL Oral Liquid, it is important to note that the medication should be taken consistently to maintain optimal control of seizure activity or tremor. The dosing regimen will vary based on the individual patient's response and tolerance to the medication. Regular monitoring by a healthcare professional is recommended to ensure the effectiveness of the treatment and to adjust the dose as necessary. As with any medication, there may be potential side effects, and patients should be counseled on what to expect and when to seek medical attention.

Bayview Pharmacy's team of compounding pharmacists is dedicated to providing high-quality, customized medications to meet the unique needs of each patient. Our expertise in compounding allows us to create formulations like Primidone 25 mg/5 mL Oral Liquid that are not readily available in commercial forms. If you have any questions or require further information about this formulation or its use in treating seizure disorders and essential tremor, please do not hesitate to reach out to us.

Drug Interactions

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Primidone is an anticonvulsant medication used to control seizures. It is metabolized in the body to phenobarbital and phenylethylmalonamide (PEMA), both of which contribute to its anticonvulsant effects. When considering the use of primidone 25 mg/5 mL oral liquid, it is important to be aware of potential drug interactions that may affect the efficacy of the medication or increase the risk of adverse effects.

Primidone can interact with other central nervous system depressants, such as alcohol, opioids, benzodiazepines, and other anticonvulsants, which can lead to increased sedation and respiratory depression. Caution is advised when co-administering these agents. Additionally, primidone may reduce the effectiveness of oral contraceptives due to its enzyme-inducing properties, and alternative or additional contraceptive measures should be considered.

Enzyme-inducing effects of primidone can also lead to increased metabolism and decreased efficacy of other medications, including warfarin, certain antipsychotics, and immunosuppressants like cyclosporine. Monitoring therapeutic drug levels and adjusting doses may be necessary when these drugs are used concurrently with primidone. Conversely, inhibitors of certain drug-metabolizing enzymes may increase primidone levels, necessitating careful monitoring and potential dose adjustments to avoid toxicity.

Primidone itself may be affected by other enzyme inducers, such as rifampin and St. John's Wort, which can decrease its plasma levels and potentially reduce its seizure control efficacy. On the other hand, drugs like valproic acid may increase primidone levels, increasing the risk of side effects such as dizziness, ataxia, and nausea.

Patients with porphyria should avoid primidone, as it may exacerbate the condition. Additionally, primidone may interact with folic acid, leading to a deficiency that can cause anemia and other hematological issues. Supplementation may be necessary in some cases.

It is crucial for patients and prescribers to be aware of all medications, supplements, and over-the-counter drugs that are being taken to avoid potential interactions with primidone. Regular monitoring, including blood tests to check drug levels and assess liver function, may be required to ensure safe and appropriate use of primidone oral liquid. If you have any questions or concerns regarding the use of this formulation or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.

How Does it Work

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The Primidone 25 mg/5 mL Oral Liquid is a specially crafted medication designed for ease of administration and precise dosing. Primidone, the active ingredient in this formulation, is a barbiturate with anticonvulsant properties. When ingested, primidone is metabolized in the liver to phenobarbital and phenylethylmalonamide (PEMA), both of which contribute to its anticonvulsant effects. This medication works by decreasing abnormal electrical activity in the brain, which is a common cause of seizures.

Upon oral administration, the liquid form of primidone is rapidly absorbed by the gastrointestinal tract, ensuring that the medication can begin to take effect in a timely manner. This is particularly beneficial for patients who require immediate relief from their symptoms. The liquid formulation is ideal for patients who have difficulty swallowing pills, such as young children, the elderly, or those with certain medical conditions that affect swallowing reflexes.

Primidone is primarily used to treat various types of seizures, including partial and generalized seizures. By stabilizing neuronal activity, primidone helps to reduce the frequency and severity of seizures and tremors, thereby improving the quality of life for individuals with these conditions.

It is important for patients and prescribers to understand that consistent blood levels of primidone and its metabolites are crucial for optimal control of seizures or tremors. Therefore, adherence to the prescribed dosing schedule is essential. The liquid formulation allows for flexible dosing, which can be adjusted according to the specific needs of the patient, under the guidance of a healthcare professional.

For any questions regarding the Primidone 25 mg/5 mL Oral Liquid, or to discuss individual patient needs and dosing adjustments, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing personalized care and support to ensure the best possible outcomes for our patients.

Frequently Asked Questions

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What is Primidone 25 mg/5 mL Oral Liquid?

Primidone 25 mg/5 mL Oral Liquid is a specifically formulated medication that contains the active ingredient primidone, a drug that is typically used to control seizures. The formulation is meant to be taken orally and is designed to provide an accurate dosage in a liquid form, which can be especially beneficial for patients who have difficulty swallowing pills, including children and the elderly.

How should Primidone Oral Liquid be taken?

This medication should be taken exactly as prescribed by your healthcare provider. The liquid form allows for flexible dosing, and the medication is usually measured with the accompanying dosing syringe or cup. It can be taken with or without food, but taking it with food may minimize gastrointestinal side effects.

Why might someone be prescribed a liquid form of Primidone instead of a tablet?

A liquid form of Primidone may be prescribed to individuals who find it hard to swallow tablets, such as young children, elderly patients, or anyone with swallowing difficulties. Liquid formulations also allow for accurate dosing adjustments and are easier to ingest for those who may be nauseous or have other conditions that make taking solid forms of medication challenging.

Can the dosage of Primidone Oral Liquid be adjusted?

Yes, one advantage of the Primidone Oral Liquid is that the dosage can be easily adjusted according to the patient's needs and response to the medication, as directed by a healthcare provider. This allows for precise dosing which is particularly important in managing seizure disorders.

Are there any special storage instructions for Primidone Oral Liquid?

Yes, Primidone Oral Liquid should be stored at room temperature, away from light and moisture. It is important not to freeze the medication, and it should be kept out of reach of children and pets. Always check the expiration date and the specific storage instructions on the label or as provided by the pharmacist or healthcare provider.

What should be done if a dose of Primidone Oral Liquid is missed?

If you miss a dose of Primidone Oral Liquid, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can lead to an overdose.

Are there any side effects associated with Primidone Oral Liquid?

Similar to other medications, Primidone Oral Liquid can cause side effects, although not everyone will experience them. Common side effects may include dizziness, sleepiness, nausea, and loss of coordination. If you experience severe side effects or signs of an allergic reaction, seek medical attention immediately.

Can Primidone Oral Liquid be taken with other medications?

Some medications may interact with Primidone Oral Liquid, so it is important to inform your healthcare provider of all medications you are currently taking, including over-the-counter drugs and supplements. They will advise you on any potential interactions and adjust your treatment as necessary.

Is Primidone Oral Liquid suitable for pregnant or breastfeeding women?

Pregnant or breastfeeding women should use Primidone Oral Liquid only if it has been specifically prescribed by a healthcare provider, and the potential benefits outweigh the risks. As with all medications, it is crucial to consult with your healthcare provider regarding the use of Primidone during pregnancy or while breastfeeding.

How do I properly measure a dose of Primidone Oral Liquid?

To accurately measure a dose of Primidone Oral Liquid, use the dosing syringe or cup that was provided with the medication. Do not use household teaspoons or tablespoons as they are not precise measuring instruments. If you did not receive a dosing device or need a replacement, ask your pharmacist for one.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Primidone 25 mg/5 mL Oral Liquid
Oral Liquid
controlled

Take orally

Three times daily