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Propranolol HCl 5 mg/ml Oral Liquid

Our Propranolol HCl 5 mg/ml Oral Liquid is a specially crafted medication designed for oral use, ensuring a precise and consistent dose of propranolol hydrochloride in each administration. This liquid formulation is particularly beneficial for patients who experience difficulty swallowing pills, including pediatric and geriatric populations. Propranolol, a beta-blocker, is effective in treating various conditions such as hypertension, angina pectoris, arrhythmias, myocardial infarction, and can also be used in the management of anxiety and thyrotoxicosis. The liquid form allows for flexible dosing and is ideal for those requiring tailored dosage adjustments.

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Oral Liquid
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Formula Information

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Propranolol HCl 5 mg/ml Oral Liquid is a specially compounded medication designed for ease of administration and precise dosing. This oral liquid formulation is particularly beneficial for patients who have difficulty swallowing pills, such as children and the elderly, or those with dysphagia. Propranolol, the active ingredient, is a non-selective beta-blocker that is widely used to manage a variety of cardiovascular conditions. It works by blocking the action of certain natural chemicals in the body, such as epinephrine, on the heart and blood vessels. This effect reduces heart rate, blood pressure, and strain on the heart.

Propranolol is effective in treating hypertension (high blood pressure), angina pectoris (chest pain), irregular heart rhythms (arrhythmias), and is also used in the prevention of migraine headaches. Additionally, it can be prescribed for the management of certain types of tremors, proliferating infantile hemangioma, and has off-label uses for anxiety. The liquid form ensures that patients who are unable to take solid forms of medication can still receive their necessary treatment without the need for tablets or capsules.

For prescribers, it is important to note that the dosing of Propranolol HCl Oral Liquid must be individualized according to the specific needs and response of the patient. Monitoring of heart rate and blood pressure is recommended during dose adjustment and periodically throughout the treatment. As with any beta-blocker, care should be taken when initiating or discontinuing therapy, and it should not be stopped abruptly. Patients with asthma or a history of bronchospasm may require special consideration due to the potential for respiratory side effects.

Patients should be counseled on the importance of taking this medication consistently and as prescribed, with instructions on how to measure and administer the liquid. They should also be made aware of potential side effects, such as dizziness, fatigue, and gastrointestinal disturbances, and advised to report any adverse reactions or concerns to their healthcare provider. It is also important for patients to inform their healthcare providers of all medications they are taking, as Propranolol can interact with other drugs.

At Bayview Pharmacy, we are committed to providing high-quality, customized medications to meet the unique needs of our patients. Our team of compounding pharmacists is available to answer any questions and provide support to both patients and prescribers regarding Propranolol HCl 5 mg/ml Oral Liquid or any other compounded medications. If you have any questions or require further information, please do not hesitate to reach out to us.

Drug Interactions

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Propranolol HCl is a non-selective beta-adrenergic receptor blocking agent, commonly used to treat a variety of cardiovascular conditions such as hypertension, angina pectoris, and arrhythmias, as well as other conditions like migraine prophylaxis, essential tremor, and certain types of anxiety disorders. When considering the use of propranolol HCl 5 mg/ml oral liquid, it is crucial to be aware of potential drug interactions that may affect the efficacy of the treatment or increase the risk of adverse effects.

Propranolol is metabolized by the liver and is a substrate for the cytochrome P450 enzyme CYP2D6. Drugs that inhibit CYP2D6, such as quinidine, fluoxetine, and paroxetine, can lead to increased plasma levels of propranolol, potentially resulting in enhanced pharmacological effects and toxicity. Conversely, inducers of CYP2D6, like rifampin and St. John's Wort, may decrease the plasma concentration of propranolol, reducing its therapeutic efficacy.

Concomitant use of propranolol with calcium channel blockers, particularly verapamil and diltiazem, can lead to an additive negative effect on heart rate, conduction, and contractility. This combination should be used with caution, and close monitoring of cardiac function is recommended. Additionally, the concurrent use of propranolol with other antihypertensive agents can potentiate the hypotensive effects and may require dosage adjustments.

Propranolol can also interact with bronchodilators like salbutamol and terbutaline. Since propranolol is a non-selective beta-blocker, it may negate the bronchodilatory effects of beta-agonists, which could be particularly problematic in patients with asthma or chronic obstructive pulmonary disease (COPD). Patients with respiratory conditions should be closely monitored, and selective beta-1 blockers may be preferred.

Patients taking insulin or oral hypoglycemic agents should be aware that propranolol may mask the signs of hypoglycemia, such as tachycardia. It can also potentiate the hypoglycemic effects of these drugs, necessitating careful blood glucose monitoring and possible adjustment of the antidiabetic medication dosage.

Propranolol may increase the serum levels of lidocaine and the anticoagulant effect of warfarin. Patients on these medications should be closely monitored for signs of toxicity and the need for dose adjustments. Additionally, concurrent use with antidepressants, particularly those with a sedative effect, may increase the risk of sedation and enhance the overall central nervous system depressant effects.

It is important to note that this is not an exhaustive list of all potential drug interactions with propranolol. Patients should be advised to inform their healthcare provider of all medications they are taking, including over-the-counter drugs, herbal supplements, and vitamins, to ensure safe and effective use of propranolol HCl oral liquid. Prescribers should consult detailed references and consider patient-specific factors when evaluating the potential for drug interactions.

If you have any questions or require further information regarding drug interactions with propranolol HCl 5 mg/ml oral liquid, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide the support and guidance needed to ensure optimal patient care.

How Does it Work

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Propranolol HCl 5 mg/ml Oral Liquid is a specially compounded medication designed for ease of administration and precise dosing. Propranolol, the active ingredient, is a non-selective beta-adrenergic receptor blocking agent, commonly referred to as a beta-blocker. This medication works by blocking the action of certain natural chemicals in your body, such as epinephrine, on the heart and blood vessels. This effect reduces heart rate, blood pressure, and strain on the heart.

Upon oral administration, Propranolol HCl is absorbed into the bloodstream from the gastrointestinal tract. Its effects are typically noted within one hour, with peak plasma concentrations occurring between one to four hours post-dose. The liquid formulation ensures that the medication can be accurately measured to the specific dose prescribed by a healthcare provider, which is particularly beneficial for patients who require individualized dosing regimens that may not be available in standard tablet or capsule forms.

Propranolol is used to treat a variety of conditions. It is commonly prescribed for hypertension (high blood pressure), angina pectoris (chest pain, usually caused by lack of oxygen to the heart due to clogged arteries), and for the prevention of migraine headaches. It is also used in the management of cardiac dysrhythmias (irregular heartbeats) and in the acute treatment of myocardial infarction (heart attack). In addition, Propranolol is used off-label for the treatment of anxiety, due to its ability to block the physical manifestations of anxiety such as rapid heartbeat and tremors.

The liquid form of Propranolol HCl is particularly useful for patients who have difficulty swallowing pills, such as young children, the elderly, or those with dysphagia (difficulty swallowing). It also allows for the administration of doses that are not available in commercially manufactured tablets or capsules, providing a tailored approach to medication management. The liquid can be mixed with certain beverages or soft foods to improve palatability if needed, although this should always be done under the guidance of a pharmacist or healthcare provider to ensure stability and efficacy of the medication.

It is important to note that Propranolol should be used with caution in patients with certain medical conditions, and it is not suitable for everyone. It is essential that patients discuss their full medical history with their healthcare provider before starting Propranolol. As with any medication, there may be potential side effects, and patients should be counseled on what to expect and when to seek medical attention.

If you have any questions about Propranolol HCl 5 mg/ml Oral Liquid or its suitability for treating specific conditions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide the information and support you need to ensure safe and effective treatment.

Other Uses

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Frequently Asked Questions

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What is Propranolol HCl 5 mg/ml Oral Liquid used for?

Propranolol HCl 5 mg/ml Oral Liquid is used to treat various heart and circulatory conditions such as high blood pressure, angina, irregular heart rhythms, and to prevent migraines. It is also used in the management of symptoms of anxiety and certain types of tremors.

How should Propranolol HCl Oral Liquid be taken?

This medication should be taken according to the prescription provided by your doctor. The liquid can be measured using a dosing syringe, cup, or spoon for accuracy. It is important to shake the bottle well before each use. It can be taken with or without food but should be taken consistently in the same manner to ensure effectiveness.

What are the benefits of using a liquid form of Propranolol?

The liquid form of Propranolol is particularly beneficial for individuals who have difficulty swallowing pills, such as children and the elderly. The ease of dosing and the ability to tailor the dose as needed make it a convenient option for many patients.

Are there any side effects associated with Propranolol HCl Oral Liquid?

Like all medications, Propranolol HCl Oral Liquid can cause side effects. Common side effects include tiredness, dizziness, and cold hands and feet. If you experience any severe or persisting side effects, it is important to contact your healthcare provider.

Can I stop taking Propranolol HCl Oral Liquid abruptly?

No, you should not stop taking Propranolol HCl Oral Liquid abruptly unless advised by your doctor. Sudden discontinuation can lead to a rapid increase in heart rate and blood pressure, among other potential symptoms. It is usually recommended to taper off the medication to avoid such adverse reactions.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and return to your regular dosing schedule. Do not double the dose to catch up.

Can the dosage of Propranolol HCl Oral Liquid be adjusted?

Yes, the dosage can be adjusted. The concentration of 5 mg/ml allows for versatile dosing that can be precisely measured to suit individual needs, as determined by a healthcare professional.

Can children take Propranolol HCl Oral Liquid?

Children may take Propranolol HCl Oral Liquid if it is prescribed by a healthcare provider for an approved condition. The dosage for children is carefully calculated based on weight and the medical condition being treated.

How should I store the Propranolol HCl Oral Liquid?

Store this medication at room temperature, away from direct light and heat. Keep the bottle tightly closed when not in use. Always check the expiration date and do not use if the medication has expired. Dispose of the medication appropriately if no longer needed.

Can Propranolol HCl Oral Liquid be taken with other medications?

Propranolol can interact with other medications, so it is essential to inform your healthcare provider about all other medicines you are taking, including over-the-counter drugs, vitamins, and herbal products. Your doctor will assess any potential interactions before prescribing Propranolol HCl Oral Liquid.

What should I do in case of an overdose?

If an overdose is suspected, seek immediate medical attention. Overdosing on Propranolol HCl Oral Liquid can be dangerous and needs to be addressed by a healthcare professional as soon as possible.

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Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.