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Sulfasalazine 50 mg/mL Oral Suspension

FDA-approved generic
Dose form
Suspension
Active ingredients
Sulfasalazine

Sulfasalazine 50 mg/mL Oral Suspension is a liquid dosage form in which sulfasalazine is uniformly dispersed throughout a liquid medium, ensuring a homogeneous mixture for precise administration. This formulation is primarily used to treat inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, by reducing inflammation in the colon and rectum.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Sulfasalazine
Suspension
66fd7b0bdc31c32733aec9f2
Service area

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Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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Sulfasalazine 50 mg/mL Oral Suspension is a compounded liquid medication formulated to deliver a precise dose of sulfasalazine in an easy-to-administer suspension. This preparation is particularly beneficial for patients who have difficulty swallowing tablets or require tailored dosing regimens, such as children or the elderly.

Sulfasalazine is an anti-inflammatory agent commonly used in the management of inflammatory bowel diseases like ulcerative colitis and Crohn's disease, as well as rheumatoid arthritis. It works by inhibiting the production of certain substances in the body that cause inflammation, thereby reducing symptoms such as pain, swelling, and diarrhea.

The oral suspension form allows for flexible dosing adjustments and ensures that the medication is evenly distributed throughout the liquid medium, providing consistent therapeutic effects with each dose.

For healthcare providers, prescribing this compounded suspension can improve patient adherence, particularly in those who are non-compliant with solid dosage forms due to swallowing difficulties or taste preferences. It also allows for dose customization to meet individual patient needs.

Patients using Sulfasalazine 50 mg/mL Oral Suspension should follow their healthcare provider's dosing instructions carefully. It is important to shake the bottle well before each use to ensure the medication is properly mixed. Regular monitoring may be necessary to assess the effectiveness of the treatment and adjust the dosage if needed.

Potential side effects may include gastrointestinal discomfort, nausea, headache, rash, or sensitivity to sunlight. Patients should report any adverse reactions to their healthcare provider promptly. It's also important to inform the provider of any other medications being taken to avoid possible drug interactions.

The suspension should be stored at room temperature, away from light and moisture, and kept out of reach of children. Do not use the medication past its expiration date, and consult the pharmacy for proper disposal methods if necessary.

If you have any questions about Sulfasalazine 50 mg/mL Oral Suspension or how it may benefit your treatment plan, please reach out to us. Our team at Bayview Pharmacy is here to support both patients and prescribers with expert advice and personalized compounding services.

Drug Interactions

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Sulfasalazine 50 mg/mL Oral Suspension is a liquid dosage form designed to provide a homogeneous mixture for administration, ensuring consistent dosing and ease of use, particularly for patients who may have difficulty swallowing tablets. This formulation is commonly used in the management of inflammatory bowel diseases such as ulcerative colitis and Crohn's disease, as well as rheumatoid arthritis.

One of the primary interactions to consider is with folic acid. Sulfasalazine can impair the absorption of folic acid, leading to a deficiency. Patients taking this medication may require folic acid supplementation to prevent deficiency-related complications, such as anemia. It is advisable for prescribers to monitor folic acid levels and adjust supplementation as necessary.

Another significant interaction is with anticoagulants such as warfarin. Sulfasalazine may enhance the effects of warfarin, increasing the risk of bleeding. Patients on both medications should have their INR levels closely monitored, and dose adjustments of the anticoagulant may be necessary to maintain therapeutic levels and minimize bleeding risks.

Sulfasalazine may also interact with digoxin, a medication used to treat heart conditions. It can reduce the absorption of digoxin, potentially leading to subtherapeutic levels and decreased efficacy. Patients on digoxin should have their serum levels monitored, and dose adjustments may be required to ensure optimal therapeutic outcomes.

Additionally, sulfasalazine can interact with certain antibiotics, such as rifampin and isoniazid, which are used to treat tuberculosis. These antibiotics can decrease the effectiveness of sulfasalazine, potentially leading to a flare-up of the underlying inflammatory condition. It is important for prescribers to consider alternative treatments or closely monitor the patient's response to therapy when these medications are used concurrently.

Patients should also be aware of potential interactions with nonsteroidal anti-inflammatory drugs (NSAIDs). While NSAIDs are often used to manage pain and inflammation, they can increase the risk of gastrointestinal side effects when taken with sulfasalazine. Patients should be advised to use NSAIDs cautiously and report any signs of gastrointestinal distress to their healthcare provider.

Lastly, sulfasalazine may interact with certain immunosuppressive agents, such as azathioprine and methotrexate, which are often used in the treatment of autoimmune conditions. These interactions can increase the risk of bone marrow suppression and other adverse effects. Regular monitoring of blood counts and liver function tests is recommended for patients receiving these combinations.

For both patients and prescribers, understanding these potential drug interactions is crucial for optimizing treatment outcomes and minimizing risks. If you have any questions or concerns about the use of Sulfasalazine 50 mg/mL Oral Suspension, please reach out to us for further guidance and support.

How Does it Work

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Sulfasalazine 50 mg/mL Oral Suspension is a compounded liquid formulation designed to deliver the active ingredient, sulfasalazine, in a uniform and easily administrable form. This suspension is particularly beneficial for patients who have difficulty swallowing tablets or require precise dosing adjustments. Sulfasalazine is a prodrug, meaning it is metabolized in the body to produce its active components, 5-aminosalicylic acid (5-ASA) and sulfapyridine, which are responsible for its therapeutic effects.

Upon oral administration, sulfasalazine is minimally absorbed in the small intestine, allowing it to reach the colon where it is cleaved by bacterial enzymes into its active metabolites. The 5-ASA component exerts its effects locally in the colon by inhibiting the production of inflammatory mediators such as prostaglandins and leukotrienes, which are involved in the inflammatory process. This action helps reduce inflammation and alleviate symptoms associated with inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease.

The sulfapyridine component, while primarily responsible for the side effects associated with sulfasalazine, also contributes to its therapeutic effects by modulating the immune response.

The liquid suspension form of sulfasalazine ensures that the medication is evenly distributed throughout the liquid medium, providing a consistent dose with each administration. This is particularly important for maintaining therapeutic levels of the drug in the body, especially in pediatric or geriatric patients who may require tailored dosing. The suspension should be shaken well before each use to ensure homogeneity and accurate dosing.

For prescribers, it is important to consider the patient's overall health status, potential drug interactions, and any history of hypersensitivity to sulfonamides or salicylates when prescribing sulfasalazine. Regular monitoring of blood counts and liver function tests is recommended due to the potential for adverse effects. Patients should be advised to report any unusual symptoms, such as rash, fever, or gastrointestinal disturbances, to their healthcare provider promptly.

If you have any questions or need further information about sulfasalazine 50 mg/mL Oral Suspension, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries or concerns you may have regarding this formulation.

Other Uses

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Sulfasalazine 50 mg/mL Oral Suspension is primarily used for the treatment of inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. However, this formulation may have other potential uses that could benefit patients with different conditions. One such use is in the management of rheumatoid arthritis, where sulfasalazine acts as a disease-modifying antirheumatic drug (DMARD). It helps reduce inflammation and slow the progression of joint damage, providing relief from pain and swelling. This liquid formulation can be particularly beneficial for patients who have difficulty swallowing tablets or require precise dosing adjustments.

Additionally, sulfasalazine has been explored for its potential benefits in treating certain dermatological conditions, such as psoriasis. Its anti-inflammatory properties may help alleviate symptoms associated with this chronic skin condition, although it is not a first-line treatment. In some cases, sulfasalazine may also be considered for use in juvenile idiopathic arthritis, offering a treatment option for children who may not tolerate other medications well. The oral suspension form allows for easier administration and dose customization, which is crucial in pediatric care.

For patients with ankylosing spondylitis, an inflammatory disease affecting the spine, sulfasalazine may provide symptomatic relief, particularly in those with peripheral joint involvement. While not the primary treatment for this condition, it can be part of a comprehensive management plan. Furthermore, there is ongoing research into the potential use of sulfasalazine in other autoimmune and inflammatory conditions, although more studies are needed to establish its efficacy and safety in these areas.

It is important for both patients and prescribers to be aware of the potential side effects and interactions associated with sulfasalazine. Common side effects include gastrointestinal discomfort, headache, and rash, while more serious reactions may involve liver function abnormalities and blood disorders. Regular monitoring and communication with healthcare providers are essential to ensure safe and appropriate use of this medication. If you have any questions or need further information about the use of Sulfasalazine 50 mg/mL Oral Suspension, please reach out to us at Bayview Pharmacy.

Frequently Asked Questions

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What is Sulfasalazine 50 mg/mL Oral Suspension?

Sulfasalazine 50 mg/mL Oral Suspension is a liquid dosage form where the active ingredient, sulfasalazine, is uniformly dispersed in a liquid medium, creating a homogeneous mixture for easy administration.

How should I store Sulfasalazine 50 mg/mL Oral Suspension?

Store the suspension at room temperature, away from direct sunlight and moisture. Ensure the bottle is tightly closed when not in use to maintain its stability and effectiveness.

How do I properly measure a dose of Sulfasalazine 50 mg/mL Oral Suspension?

Use a medical-grade measuring device, such as an oral syringe or a dosing cup, to ensure you are administering the correct dose. Avoid using household spoons as they may not provide an accurate measurement.

Can Sulfasalazine 50 mg/mL Oral Suspension be mixed with food or drinks?

Consult your healthcare provider before mixing the suspension with food or drinks, as this may affect the absorption or effectiveness of the medication.

What should I do if I miss a dose of Sulfasalazine 50 mg/mL Oral Suspension?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

Are there any side effects associated with Sulfasalazine 50 mg/mL Oral Suspension?

Common side effects may include nausea, headache, and loss of appetite. If you experience severe side effects such as difficulty breathing, severe rash, or yellowing of the skin, seek medical attention immediately.

Can children use Sulfasalazine 50 mg/mL Oral Suspension?

Sulfasalazine 50 mg/mL Oral Suspension can be prescribed to children, but the dosage and administration should be determined by a healthcare provider based on the child's specific needs and medical condition.

How long does it take for Sulfasalazine 50 mg/mL Oral Suspension to work?

The time it takes for sulfasalazine to work can vary depending on the condition being treated. Some patients may notice improvement within a few days, while others may require several weeks to experience the full benefits.

Can I stop taking Sulfasalazine 50 mg/mL Oral Suspension if I feel better?

Do not stop taking the medication without consulting your healthcare provider, even if you feel better. Stopping the medication abruptly may cause your symptoms to return or worsen.

What should I do if I experience an allergic reaction to Sulfasalazine 50 mg/mL Oral Suspension?

If you experience symptoms of an allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat, seek emergency medical attention immediately.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Sulfasalazine 50 mg/mL Oral Suspension
Suspension
30 mL
controlled

Take orally

Twice daily