Theophylline 25 mg/ml Oral Liquid is a specially compounded medication designed for oral use, providing a precise concentration of theophylline in a liquid form. This formulation is particularly beneficial for patients who have difficulty swallowing pills, such as children and the elderly, or for those who require a dosage that is not readily available in commercial tablet or capsule forms. Theophylline is a bronchodilator that is commonly used to treat and manage symptoms of asthma and chronic obstructive pulmonary disease (COPD). It works by relaxing the muscles in the lungs and chest, making it easier to breathe and helping to prevent the wheezing, shortness of breath, and chest tightness associated with these conditions.

The 25 mg/ml concentration allows for flexible dosing tailored to the specific needs of the patient, which can be adjusted based on the severity of the symptoms, the patient's response to the medication, and their overall health status. The liquid form ensures that the medication can be measured accurately with a syringe or dropper, providing a reliable and consistent dose with each administration. It is important for prescribers to monitor the patient's serum theophylline levels to avoid potential toxicity and to adjust the dose as necessary to achieve therapeutic levels.

Patients should be advised on the proper administration of theophylline oral liquid, including the importance of consistent dosing intervals and adherence to the prescribed regimen. They should also be informed of potential side effects, such as nausea, vomiting, insomnia, and palpitations, and instructed to contact their healthcare provider if they experience any adverse reactions or if their symptoms do not improve. Additionally, patients should be counseled on the importance of avoiding certain foods, beverages, and medications that may interact with theophylline, as well as the necessity of regular follow-up appointments to monitor their condition and the effectiveness of the medication.

For prescribers considering this formulation for their patients, it is essential to take into account the patient's complete medical history, including any comorbid conditions and concurrent medications, to avoid potential drug interactions and to ensure the safe use of theophylline. Dosing should be individualized and titrated based on therapeutic response and serum drug levels. Theophylline has a narrow therapeutic index, and careful monitoring is crucial to prevent toxicity.

If you have any questions or require further information about theophylline 25 mg/ml Oral Liquid, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing support and guidance to ensure the safe and effective use of this medication for your patients.

Theophylline is a bronchodilator used to treat symptoms of asthma, chronic bronchitis, emphysema, and other lung diseases. It works by relaxing muscles in the lungs and chest, making it easier to breathe. When considering the use of theophylline 25 mg/ml oral liquid, it is important to be aware of potential drug interactions that can affect the efficacy of the medication or increase the risk of adverse effects.

One major interaction is with other medications that affect the cytochrome P450 enzyme system, particularly CYP1A2, CYP3A4, and CYP2E1. Drugs that inhibit these enzymes, such as cimetidine, fluvoxamine, and erythromycin, can decrease theophylline clearance and increase the risk of toxicity. Conversely, medications that induce these enzymes, such as rifampin and phenobarbital, can increase the clearance of theophylline, potentially reducing its effectiveness.

Other notable interactions include adenosine, which theophylline can antagonize, potentially reducing the effectiveness of adenosine in treating certain cardiac conditions. Theophylline may also increase the risk of side effects from beta-blockers, such as propranolol, by reducing their clearance. Additionally, theophylline can decrease the effectiveness of lithium and phenytoin by increasing their clearance. It is also important to monitor theophylline levels when co-administered with fluoroquinolone antibiotics, as they can both increase theophylline levels and risk of toxicity.

Non-prescription products can also interact with theophylline. For example, certain herbal supplements such as St. John's Wort may decrease theophylline levels, while caffeine can increase the side effects of theophylline due to their similar pharmacologic effects. Patients should be advised to inform their healthcare provider of all medications, supplements, and over-the-counter drugs they are taking.

Food and drink can also affect theophylline levels. A high-protein, low-carbohydrate diet can increase theophylline clearance, while a high-carbohydrate, low-protein diet can decrease it. Smoking tobacco or marijuana can increase the clearance of theophylline, necessitating dosage adjustments. Conversely, cessation of smoking can decrease the clearance of theophylline and increase the risk of toxicity.

It is crucial for patients to have their theophylline levels monitored regularly to ensure they remain within the therapeutic range, especially when starting, stopping, or changing the dosage of any medications that may interact with theophylline. Signs of theophylline toxicity include nausea, vomiting, insomnia, seizures, and arrhythmias. If patients experience any of these symptoms, they should seek medical attention immediately.

For more detailed information on theophylline interactions or if you have any questions regarding the use of theophylline 25 mg/ml oral liquid, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure safe and effective treatment with this medication.

Theophylline is a bronchodilator that is used to treat symptoms of asthma, chronic bronchitis, emphysema, and other lung diseases. It works by relaxing the smooth muscles of the bronchial airways, thus reducing airway constriction and making it easier to breathe. Theophylline achieves this by inhibiting the enzyme phosphodiesterase, which leads to an increase in cyclic adenosine monophosphate (cAMP) within the smooth muscle cells. Elevated levels of cAMP result in bronchodilation. Additionally, theophylline has anti-inflammatory effects and can enhance the strength of diaphragmatic contractions, further aiding in respiration.

The formulation of theophylline as a 25 mg/ml oral liquid is designed to provide a precise dosage that can be easily adjusted according to the patient's needs and response to therapy. This is particularly important with theophylline, as it has a narrow therapeutic index, meaning that the effective and toxic doses are close to each other. Regular monitoring of theophylline blood levels is often required to ensure therapeutic levels are maintained without reaching toxic concentrations. The liquid form is especially beneficial for patients who have difficulty swallowing pills, such as young children or elderly patients, and allows for flexible dosing.

When administered, the theophylline oral liquid is absorbed from the gastrointestinal tract and distributed throughout the body. It is metabolized primarily in the liver and its metabolites are excreted through the kidneys. The half-life of theophylline can vary significantly between individuals, and factors such as age, smoking, and other medications can affect its metabolism. Therefore, dosing regimens are individualized for each patient to achieve optimal therapeutic effects.

Patients and prescribers should be aware that certain conditions and medications can interact with theophylline, potentially leading to increased side effects or a need for dosage adjustments. For example, heart disease, liver disease, and concurrent use of other medications that affect theophylline levels should be discussed with a healthcare provider. Common side effects of theophylline include nausea, headache, insomnia, and irritability, though more severe effects can occur at higher concentrations.

Bayview Pharmacy's team of compounding pharmacists is dedicated to providing high-quality, customized medications to meet the unique needs of each patient. Our theophylline 25 mg/ml oral liquid is compounded with precision and care, ensuring that each dose is accurate and effective for the treatment of respiratory conditions. If you have any questions about this formulation or how it can be integrated into your treatment plan, please reach out to us for more information and guidance.

The theophylline 25 mg/ml oral liquid is primarily prescribed for respiratory conditions such as chronic obstructive pulmonary disease (COPD) and asthma due to its bronchodilator properties, which help to open the airways in the lungs, making it easier to breathe. However, beyond these common indications, theophylline has also been used in other disease states, although these are less common and sometimes considered off-label uses.

For instance, some studies have suggested that theophylline may improve diaphragmatic contractility, and therefore, it has the potential to be used in conditions that involve diaphragm weakness or dysfunction. In addition, due to its ability to stimulate the central nervous system, it has been occasionally employed in the management of apnea of prematurity, a condition commonly seen in premature infants.

Furthermore, theophylline has been explored for its anti-inflammatory effects in chronic heart failure and intermittent claudication, where improving blood flow can be beneficial. Its use in these conditions, however, is not widely accepted and should be approached with caution, considering the availability of more conventional therapies with established safety profiles. Theophylline requires careful monitoring due to its narrow therapeutic index and the potential for significant side effects. Clinicians sometimes consider serum theophylline levels to optimize therapy within the therapeutic range and minimize adverse effects.

It is essential to recognize that the use of theophylline in other disease states, beyond COPD and asthma, should be guided by clinical evidence and undertaken with a thorough understanding of the patient's overall health condition. Both patients and prescribers are encouraged to discuss all possible treatment options and the appropriateness of theophylline for their specific cases. As with any medication, the potential benefits must be weighed against the risks, and decisions should be tailored to individual patient needs.

Bayview Pharmacy is committed to ensuring that each patient receives personalized care. Our team is available to provide further information on this theophylline formulation and to answer any questions regarding its uses. We encourage patients and prescribers to reach out to us for guidance and support in utilizing this medication safely and effectively.