Check out our most popular compounded medications! Get Started
The Urea 40% Topical Gel is a highly concentrated, semisolid formulation designed for targeted treatment of various skin conditions. This gel is dispensed through a pump mechanism, which allows for easy and precise application.
Urea serves as a keratolytic and hydrating agent, making this formulation particularly useful in the treatment of hyperkeratotic conditions such as psoriasis, ichthyosis, and keratosis pilaris. It also aids in the management of onychomycosis and calluses by softening the skin and nails, thereby enhancing the penetration of other topical treatments. Additionally, the Urea 40% Topical Gel is beneficial for patients with xerosis or dry skin, as it helps to restore the skin's natural moisture balance.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Urea 40% Topical Gel is a highly concentrated, semisolid formulation designed to provide targeted treatment for a variety of dermatological conditions. This gel is dispensed through a pump mechanism, which ensures ease of use and precise dosing. The pump allows patients to apply the medication directly to the affected areas without the mess often associated with creams and ointments. The gel base facilitates rapid absorption of urea into the skin, enhancing its therapeutic effects.
Urea, the active ingredient in this formulation, is a potent keratolytic and hydrating agent. It works by increasing the water content in the stratum corneum, the outermost layer of the skin, which softens and dissolves the protein that holds the dead skin cells together. This action helps to exfoliate the skin, promoting the shedding of scaly, keratinous material.
In addition to its keratolytic properties, urea also enhances the penetration of other medications, making it an excellent adjunct in combination therapies. For instance, when used with topical corticosteroids, it can improve the anti-inflammatory effects by facilitating deeper delivery of the corticosteroid into the skin layers. Furthermore, urea has been shown to have antimicrobial properties, which can be beneficial in minimizing the risk of infections associated with cracked or fissured skin.
Patients using Urea 40% Topical Gel should be advised that it may cause temporary burning, stinging, or irritation upon application, particularly if applied to broken or inflamed skin. It is important to follow the prescribed dosing instructions and to avoid contact with the eyes, mouth, or other mucous membranes. Prescribers should consider the patient's overall skin condition and any concurrent skin therapies when recommending this treatment to ensure optimal results and minimize potential adverse effects.
For those interested in Urea 40% Topical Gel, whether patients or healthcare providers, we at Bayview Pharmacy are available to answer any questions and provide additional information. Our team of compounding pharmacists is committed to supporting your dermatological needs with high-quality, customized formulations.
Urea 40% topical gel is a keratolytic agent that is commonly used to hydrate and soften the skin, particularly in conditions such as psoriasis, eczema, corns, callus formations, and some nail problems. When considering the use of urea 40% topical gel, it is important to be aware of potential drug interactions that may affect its efficacy or the safety of the patient.
While urea is not known to have significant interactions with systemic medications due to its limited absorption through the skin, it is still crucial to consider the effects of other topical products used concurrently. The use of other topical agents, particularly those that may also have keratolytic properties or alter skin barrier function, could potentially enhance the irritation or sensitivity of the skin. For example, concomitant use of topical retinoids, alpha hydroxy acids (such as glycolic acid), or salicylic acid with urea 40% topical gel may increase the risk of local skin irritation. Patients should be advised to inform their healthcare provider of all topical products they are using to assess for potential interactions.
Additionally, the application of urea 40% topical gel under occlusion, such as with bandages or occlusive dressings, may increase the absorption of urea as well as other topical medications. This could potentially lead to increased effects or adverse reactions. Therefore, caution should be exercised when using occlusive dressings over areas treated with urea 40% topical gel, and healthcare providers should be consulted before combining such treatments.
It is also important to consider the timing of application when using multiple topical products. To minimize potential interactions, it is generally recommended to apply different topical agents at different times of the day or to allow sufficient time between applications for the product to be absorbed or to avoid potential changes in the efficacy of either product.
Patients with pre-existing skin conditions or those with sensitive skin may be more susceptible to irritation from topical products, and the addition of urea 40% topical gel may exacerbate these conditions. It is advisable for these patients to start with a lower concentration of urea and to consult with their healthcare provider before using the 40% formulation.
As with any medication, it is essential to use urea 40% topical gel as directed by a healthcare provider and to report any unusual skin reactions or worsening of the condition. If you have any questions or concerns about the use of urea 40% topical gel or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.
Urea 40% Topical Gel is a highly concentrated formulation designed to provide keratolytic and hydrating effects when applied to the skin. Urea, the active ingredient, is a potent humectant, which means it has the ability to draw moisture into the skin. This is particularly beneficial for patients with dry, rough, or scaly skin conditions, as it helps to hydrate the stratum corneum (the outermost layer of the skin) and enhance the skin's water-binding capacity.
The mechanism by which Urea 40% Topical Gel works involves the breakdown of the protein structure within the skin, which in turn softens and dissolves the intercellular matrix. This process helps to shed dead skin cells from the skin's surface, promoting desquamation and increasing cell turnover. As a result, the skin becomes smoother and more pliable. The high concentration of urea in this formulation also has a mild antipruritic effect, which can help alleviate itching associated with dry skin conditions.
In psoriasis, for example, urea helps to reduce the scaling and thickness of plaques, while in ichthyosis and similar conditions, it aids in normalizing the process of skin shedding and reduces the buildup of scales.
The semisolid gel formulation of Urea 40% Topical Gel is specifically designed for ease of use and targeted application. The gel consistency allows for the product to stay in place on the skin, ensuring that the active ingredient is absorbed where it is needed most. The pump mechanism of the container dispenses a consistent amount of product with each use, which helps patients apply the correct dose and minimizes waste. This delivery system is particularly useful for patients who may have difficulty with manual dexterity or who prefer a no-mess application method.
For optimal results, patients should apply Urea 40% Topical Gel as directed by their healthcare provider, typically to clean, dry skin. It is important to avoid contact with the eyes, mouth, or other mucous membranes, and to use the product only on the areas of skin that require treatment. Patients should also be advised that they may experience a mild stinging sensation upon application, particularly if the skin is cracked or broken. However, this is generally transient and should diminish with continued use.
Prescribers considering Urea 40% Topical Gel for their patients should be aware of its indications, mechanism of action, and the benefits of its gel formulation. This product is a valuable option for managing and treating challenging skin conditions that require both exfoliation and hydration. If you have any questions or require further information about Urea 40% Topical Gel, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to support both patients and healthcare providers with expert advice and customized care.
Urea 40% Topical Gel is a high-concentration urea-based skin care product used to treat a variety of skin conditions that result in dry, rough, and thickened skin, such as eczema, psoriasis, corns, callus formations, and some nail problems. The urea acts as a keratolytic and humectant that helps to moisturize and soften the skin.
Apply a thin layer of the Urea 40% Topical Gel to the affected area of skin, usually twice daily or as directed by your healthcare provider. Rub in gently until the gel is fully absorbed. Wash your hands immediately after use unless the treatment area includes the hands.
The gel is intended for external use on skin only. Avoid application on the face, near the eyes, or on sensitive or broken skin, unless directed by a healthcare provider. It is best to use the gel on keratinized areas such as elbows, knees, heels, and other thickened skin.
While Urea 40% Topical Gel is beneficial for many with dry and thickened skin, individuals with sensitive skin or specific allergies should consult a healthcare provider before use. A patch test can determine if you have a reaction to the product.
Potential side effects can include mild burning, irritation, or stinging when the gel is first applied to the skin. If any of these effects persist, or if you experience severe pain, redness, or irritation, contact your healthcare provider immediately.
In many cases, Urea 40% Topical Gel does require a prescription. Check with your local pharmacy or healthcare provider to understand the regulations and obtain a prescription if necessary.
When using with other skincare products, apply Urea 40% Topical Gel first and allow it to be absorbed into the skin before applying other products. Be cautious about mixing active ingredients and consult with a healthcare provider or dermatologist to ensure compatibility.
Store the Urea 40% Topical Gel at room temperature, away from heat and direct light. Do not freeze the medication and keep it out of reach of children and pets.
If you miss a dose, apply the gel as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your usual dosing schedule. Do not double up to make up for a missed dose.
Urea 40% Topical Gel can increase your skin's sensitivity to sunlight. If you are going outdoors, apply sunscreen and wear protective clothing over the treated areas to prevent sunburn. Discuss with your healthcare provider about any additional precautions you should take.
The pump mechanism of the Urea 40% Topical Gel packaging provides a convenient and hygienic method of dispensing the product, allowing for precise dosing and targeted application to the specific areas of the skin that require treatment without unnecessary waste or mess.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
