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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Prepared to a prescriber's order for one patient. Not FDA-approved.
Vancomycin is a glycopeptide antibiotic that compounding pharmacies prepare as oral liquids, capsules and sterile preparations such as eye drops by prescription.
Vancomycin is a glycopeptide antibiotic active only against Gram-positive bacteria. It binds a building block of the bacterial cell wall (D-alanyl-D-alanine), blocking wall construction so the cell leaks and dies. Taken by mouth it is poorly absorbed and acts inside the intestine. Vancocin capsules (ANI) and Firvanq oral solution kit (Azurity) are FDA-approved in adults and children for Clostridioides difficile-associated diarrhea and Staphylococcus aureus enterocolitis, including methicillin-resistant strains. Vancomycin hydrochloride for injection (for example Hospira) is approved intravenously for serious or severe infections caused by susceptible methicillin-resistant staphylococci and other susceptible organisms, including endocarditis. A prescriber may order vancomycin compounded as an oral liquid or capsule in a strength or flavor not manufactured, or as a sterile preparation for another route. Compounded preparations are not FDA-approved and require a prescription.
Vancomycin does not carry a boxed warning. Do not use it if you are allergic to vancomycin. The labels warn of kidney damage, hearing loss and severe skin reactions; stop and call your prescriber at the first sign of rash, blisters or mouth sores. Oral vancomycin is meant only for intestinal infections, yet some patients taking repeated oral doses have had measurable blood levels and kidney injury, especially older adults. The injection label warns that vancomycin injected into the eye during or after cataract surgery has caused hemorrhagic occlusive retinal vasculitis with permanent vision loss. Other drugs that can harm the kidneys or hearing, such as aminoglycosides, amphotericin and loop diuretics, add to the risk. Little vancomycin reaches breast milk, and LactMed says no special precautions are required. For reduced urination, ringing in the ears or hearing loss, talk to your prescriber or pharmacist.
Vancomycin inhibits peptidoglycan polymerization by binding D-alanyl-D-alanine, blocking cell wall synthesis and cross-linking. Oral bioavailability is under 10 percent and oral drug is excreted mainly in feces, though the Vancocin label notes clinically significant serum concentrations in some patients with active C. difficile disease after multiple doses. After IV dosing, protein binding is about 55 percent, CSF penetration is poor without inflamed meninges, terminal half-life is about 4 to 6 hours with normal renal function, prolonged in renal impairment, and most of the dose is cleared by glomerular filtration. Labeled indications: oral Vancocin and Firvanq for C. difficile-associated diarrhea and staphylococcal enterocolitis; IV vancomycin for serious susceptible Gram-positive infections. StatPearls lists off-label uses including intravitreal administration for bacterial endophthalmitis and rectal administration for C. difficile infection, and states intrathecal use is not FDA-approved. Dosing per prescriber. Monitor renal function, blood counts and hearing; for systemic therapy, StatPearls describes trough or AUC-guided monitoring per IDSA, ASHP and PIDS guidance. The injection label states vancomycin is not indicated for intracameral or intravitreal endophthalmitis prophylaxis. Vancomycin is not a controlled substance.
Wash your hands. Open one capsule and empty the powder into the volume of saline or water on your label, using only distilled, sterile, or boiled and cooled water if you are mixing it yourself. Stir or shake until dissolved. For a sinus rinse, lean over a sink and rinse each nostril with the device. For a nebulizer, pour the solution into the medicine cup and breathe normally through the mouthpiece or mask until the mist stops. Wash and air dry the rinse device or nebulizer cup after each use. Discard any mixed solution you do not use.
Keep the unopened capsules tightly closed in a dry place at room temperature and out of reach of children. The beyond-use date on your label depends on how the capsules were prepared and what they are for; the pharmacist sets it. Mix only one dose at a time and discard capsules after the beyond-use date on your label.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Empty contents of 1 capsule and mix with saline solution and irrigate/nebulize
