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Albendazole is a broad-spectrum anthelmintic agent widely used in the treatment of parasitic worm infestations.
Albendazole is a broad-spectrum anthelmintic agent widely used in the treatment of various parasitic worm infestations. It is particularly effective against nematodes, cestodes, and certain protozoa, making it a versatile choice in managing conditions such as neurocysticercosis, echinococcosis, and giardiasis. Its mechanism of action involves the inhibition of microtubule polymerization by binding to beta-tubulin, which disrupts essential cellular processes in parasites, leading to their eventual death.
Albendazole is metabolized in the liver to its active form, albendazole sulfoxide, which is responsible for its therapeutic effects. This transformation is crucial for its efficacy, as the active metabolite has a higher affinity for parasitic beta-tubulin compared to mammalian cells, ensuring selective toxicity. The pharmacokinetics of albendazole can be influenced by factors such as food intake, with a high-fat meal significantly enhancing its absorption and bioavailability.
In clinical practice, albendazole is often preferred due to its broad spectrum of activity and favorable safety profile. It is generally well-tolerated, with mild side effects such as gastrointestinal discomfort, headache, and dizziness being the most commonly reported. However, prescribers should exercise caution in patients with liver impairment or those who are pregnant, as albendazole is contraindicated in the first trimester due to potential teratogenic effects.
Albendazole's role in the management of parasitic infections is further supported by its inclusion in various treatment guidelines and its availability in multiple formulations, allowing for tailored therapeutic approaches. Its use in compounded formulations can provide additional flexibility in dosing and administration, particularly for patients with specific needs or those who require alternative delivery methods. This adaptability makes albendazole a valuable component in the arsenal against parasitic diseases, offering both efficacy and convenience for healthcare providers and patients alike.
Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.
We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.
Prescriber sign inA sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.
Other salt forms of this molecule, and ingredients commonly compounded alongside it.
This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.
Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.
Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.
