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Active pharmaceutical ingredient

Amikacin Sulfate

Amikacin Sulfate is a potent aminoglycoside antibiotic used in various compounded formulations to treat severe bacterial infections.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Amikacin Sulfate is a potent aminoglycoside antibiotic used in various compounded formulations to treat severe bacterial infections. It is particularly effective against Gram-negative bacteria, including strains resistant to other antibiotics, making it a critical option in the management of complex infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, inhibiting protein synthesis and ultimately leading to bacterial cell death.

Due to its broad-spectrum activity, Amikacin Sulfate is often utilized in cases where other antibiotics have failed or when the causative organism is unknown. Its pharmacokinetic properties allow for effective penetration into tissues, including the lungs and kidneys, which are common sites of infection. However, careful monitoring of serum levels is essential to minimize potential nephrotoxicity and ototoxicity, which are known side effects associated with aminoglycosides.

In clinical practice, Amikacin Sulfate is frequently used in combination with other antibiotics to enhance its efficacy and broaden the spectrum of antibacterial activity. This synergistic approach is particularly beneficial in treating multi-drug resistant infections. Prescribers should consider patient-specific factors such as renal function and potential drug interactions when incorporating Amikacin into treatment regimens.

Amikacin Sulfate's role in compounded formulations allows for tailored dosing and delivery methods, optimizing therapeutic outcomes for individual patients. This customization is especially valuable in pediatric and geriatric populations, where standard dosing may not be appropriate. By leveraging the unique properties of Amikacin Sulfate, compounded formulations can provide targeted and effective treatment options for challenging bacterial infections.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.